Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature

Imtiaz Ahmed; Sapna Krishnamurthy; Aanchal Kakkar; Pramod Kumar Julka; Goura Kishor Rath

doi:10.4103/0971-5851.133729

Indian Journal of Medical and Paediatric Oncology, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2014; 35(01): 86-88
DOI: 10.4103/0971-5851.133729

CASE REPORT

Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature

Autor*innen

Imtiaz Ahmed

Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India
Sapna Krishnamurthy

Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India
Aanchal Kakkar

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
Pramod Kumar Julka

Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India
Goura Kishor Rath

Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India

Abstract

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Abstract

A 6½-year-old boy had developed acute lymphoblastic leukemia and was treated with systemic chemotherapy, intrathecal triple drug regimen and prophylactic cranial irradiation. After 10 years he developed anaplastic astrocytoma of the postero-superior cerebellum on the left side while leukemia was in remission. He was treated with surgical excision, followed by adjuvant three dimensional conformal radiotherapy and is on salvage chemotherapy with temozolamide. It is possible that the anaplastic astrocytoma may be a radiation induced malignancy.

Keywords

Acute lymphoblastic leukemia - anaplastic astrocytoma - prophylactic cranial irradiation

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Referenzen

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