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CC BY-NC-ND 4.0 · J Lab Physicians 2009; 1(01): 022-024
DOI: 10.4103/0974-2727.54803
Case Report

Immune Hemolytic Anemia: A Report of Two Cases

Paramjit Kaur
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India
,
Sabita Basu
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India
,
Ravneet Kaur
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India
,
Gagandeep Kaur
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India
› Institutsangaben Source of Support: Nil
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ABSTRACT

The transfusion-medicine specialists and physicians are often in a difficult situation when the patient has severe worsening anemia and all the blood is mismatched. This situation can arise in patients with red cell autoantibodies or alloantibodies due to previous transfusions. We report two cases of immune hemolysis - one due to warm auto antibodies and the second due to alloimmunization from multiple transfusions.

Keywords

Auto antibodies - hemolysis - alloimmunization - blood transfusion


Publikationsverlauf

Artikel online veröffentlicht:
29. Januar 2020

© 2009.

Thieme Medical and Scientific Publishers Private Ltd.
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  • REFERENCES

  • 1 Conley CL, Lippman SM, Ness PM. Autoimmune haemolytic anaemia with reticulocytopenia: a medical emergency. JAMA 1980;244:1685.
  • 2 Pirofsky B. Auto immunization and the auto immune haemolytic anaemias. Baltimore: Williams and Wilkins; 1969.
  • 3 Bottiger LE, Westerholm B. Acquired haemolytic anaemia. Incidence and aetiology. Acta Med Scand 1973;193:223-6.
  • 4 Linden JV, Paul B, Dressler KP. A report of 104 transfusion errors in New York State. Transfusion 1992;32:601-6.
  • 5 Heddle NM, Soutar RL, O′Hoski PL, Singer J, Mc Bride JA, Ali MA, et al. A prospective study to determine the frequency and clinical significance of allo immunization post transfusion. Br J Hematol 1995;91:1000-5.
  • 6 Vamvakas EC, Pineda AA, Reisner P, Santranch PJ, Moore SB. The differentiation of delayed hemolytic and serologic transfusion reactions: incidence and predictors of haemolysis. Transfusion 1995;35:26-32.
  • 7 Ness PM, Shirey RS, Thomas SK, Buck SA. The differentiation of delayed serologic and delayed hemolytic transfusion reactions: incidence, long term serologic findings and clinical significance. Transfusion 1990;30:688-93.
  • 8 Sokol RJ, Hewitt S, Stamps BK. Autoimmune hemolysis: an 18 year study of 865 cases referred to a regional transfusion centre. Br Med J 1981;282:2023-7.
  • 9 Petz LD, Garraty G. Acquired immune hemolytic anemias. New York: Churchill Livingstone; 1980.
  • 10 Gehrs BC, Friedberg RC. Autoimmune haemolytic anaemia. Am J Hematol 2002;69:258-71.
  • 11 Petz LD, Garratty G. Immune haemolytic anemias. 2nd ed. 2004.
  • 12 Ness PM. How do I encourage clinicians to transfuse mismatched blood in patients with autoimmune haemolytic anaemia in urgent situations? Transfusion 2006;46:1859-62.
  • 13 Meny G. Review: Transfusing incompatible RBCs - clinical aspects. Immunohemat 2004;20:161-6.
  • 14 Shirey RS, Boyd JS, Parwani AV, Tanz WS, Ness PM, King KE. Prophylactic antigen matched donor blood for patients with warm aotuantibodies: an algorithm for transfusion management. Transfusion 2002;42:435-41.
  • 15 Lostumbo MM, Holland PV, Schmidt PJ. Isoimmunisation after multiple transfusions. N Engl J Med 1966;275:141-4.
  • 16 Blumberg N, Peck K, Ross K, Avila E. Immune response to chronic red blood cell transfusion. Vox Sang 1983;44:212-7.
  • 17 Brantley SG, Ramsey G. Red cell alloimmunisation in multi transfused HLA typed patients. Transfusion 1988;28:463-6.
  • 18 Ramsey G, Cornell FW, Hahn LF, Larson P, Issitt LB, Starzl TE. Red cell antibody problems in 1000 liver transplants. Transfusion 1989;29:396-400.
  • 19 Fluit CR, Kunst VA, Drenthe-Schonke AM. Incidence of red cell antibodies after multiple blood transfusions. Transfusion 1990;30:532-5.
  • 20 Poole J, Daniels G. Blood group antibodies and their significance in transfusion medicine. Trans Med Rev 2007;21:58-71.
  • 21 Redman M, Regan F, Contreras M. A prospective study of the incidence of red cell allo immunization following transfusion. Vox Sang 1996;71:216-20.
  • 22 Hoeltge GA, Domen RE, Rybicki LA, Schaffer PA. Multiple red cell transfusions and allo immunization. Arch Pathol Lab Med 1995;119:42-5.
  • 23 Takeuchi C, Ohto H, Miura S, Yasuda H, Ono S, Ogata T. Delayed and acute hemolytic transfusion reactions resulting from red cell antibodies and red cell reactive HLA antibodies. Transfusion 2005;45:1925-9.