CC BY-NC-ND 4.0 · Avicenna J Med 2015; 05(03): 79-82
DOI: 10.4103/2231-0770.160234

Brainstem auditory evoked potential in clinical hypothyroidism

Kirti Sharma
Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India
Naresh Kumar
Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India
Joshil Kumar Behera
Department of Physiology, Government Medical College, Srinagar, Pauri Garhwal, Uttarakhand, India
Sushma Sood
Department of Physiology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Sibadatta Das
Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India
Harnam Singh Madan
Department of Orthopedics, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India
› Author Affiliations
Financial support and sponsorship Nil.


Objectives: The association of hypothyroidism with impairment of hearing is known to occur. It may be of any kind i. e., conductive, sensorineural or mixed. The aim of this study is to assess auditory pathway by brainstem auditory evoked potential (BAEP) in newly diagnosed patients of clinical hypothyroidism and healthy sex- and age-matched controls. Materials and Methods: The study included 25 healthy age- and sex-matched controls (Group I) and 25 patients of newly diagnosed clinical hypothyroidism (Group II). The recording was taken by using RMS EMG EP MK2 equipment. Statistical Analysis Used: Unpaired Student′s t test. Results: There was a significant increase in wave IV (5.16 ± 0.85 ms) and wave V (6.17 ± 0.89 ms) latencies of right ear BAEP of Group II in comparison to wave IV (4.66 ± 0.39 ms) and wave V (5.49 ± 0.26 ms) of Group I. Wave V of left ear BAEP of Group II was also prolonged (6 ± 0.61 ms) in comparison to Group I (5.47 ± 0.35 ms). There was a significant difference in inter-peak latencies IPL I -V (4.44 ± 0.66 ms) and IPL III -V (2.2 ± 0.5 ms) of right ear BAEP of Group II in comparison to IPL I -V (3.94 ± 0.31 ms) and IPL III -V (1.84 ± 0.34 ms) of Group I. A significant prolongation was also found of IPL I -V (4.36 ± 0.59 ms) and IPL III -V (2.2 ± 0.42 ms) of left ear BAEP of Group II in comparison to IPL I -V (3.89 ± 0.3 ms) and IPL III -V (1.85 ± 0.3 ms) of Group I. Conclusion: Prolongation of wave IV and V along with inter-peak latencies in BAEP of both ears suggests that central auditory pathway is affected significantly in clinical hypothyroid patients.

Publication History

Article published online:
09 August 2021

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