Abstract
Cutaneous adverse reactions are a common complication of anti-retroviral therapy.
Tenofovir is a newer anti-retroviral drug belonging to the nucleotide reverse transcriptase
inhibitor group. Systemic adverse effects like nausea, vomiting, diarrhea, hepatotoxicity
and renal toxicity are common with tenofovir but cutaneous adverse effects are rare.
Lichenoid drug eruptions are a common adverse effect seen with a large variety of
drugs including antimalarials, antihypertensives, nonsteroidal anti-inflammatory drugs
and diuretics. Lichenoid drug eruption is a rare cutaneous adverse effect of tenofovir
with only a single case reported till date. Here, we report a case of tenofovir induced
lichenoid drug eruption in a 54-year-old human immunodeficiency virus affected male
who presented with generalized lichenoid eruption after 6 weeks of initiation of tenofovir
and complete clearance on cessation of the drug.
Keywords
Cutaneous adverse drug reaction - lichenoid drug eruption - tenofovir
