Issues in current management of chronic myeloid leukemia: Importance of molecular monitoring on long term outcome

Hari Menon

doi:10.4103/2278-330X.105893

South Asian Journal of Cancer, Table of Contents

CC BY-NC-ND 4.0 · South Asian J Cancer 2013; 02(01): 038-043
DOI: 10.4103/2278-330X.105893

Review Article

Issues in current management of chronic myeloid leukemia: Importance of molecular monitoring on long term outcome

Authors

Hari Menon

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India

Abstract

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Abstract

Monitoring of CML patients while on therapy is vitally important and ENL has come up with specific guidelines for the same. Since we are currently talking about operational cure, this review shall focus on evaluating the emerging data to optimize response. This requires attention to all outstanding controversial issues. Only careful, accurate and regular monitoring with specific attention to grey areas will help us select first line therapy, decide when to discontinue TKIs and also move to second line TKIs in a timely manner.

Key words

Monitoring - polymerase chain reaction - remission - tyrosine kinase inhibitor - hematopoietic stem cell transplantation

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References

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