Organ preservation strategies: Review of literature and their applicability in developing nations

Mitali Dandekar; Anil D'Cruz

doi:10.4103/2278-330X.136764

South Asian Journal of Cancer, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · South Asian J Cancer 2014; 03(03): 147-150
DOI: 10.4103/2278-330X.136764

MINI SYMPOSIUM: HEAD AND NECK CANCER : Review Article

Organ preservation strategies: Review of literature and their applicability in developing nations

Autor*innen

Mitali Dandekar

Department of Head Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India
Anil D'Cruz

Department of Head Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India

Abstract

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Abstract

There has been a change in practice in locally advanced laryngopharyngeal cancers toward non-surgical treatment modalities. Although, there have been landmark trials pertinent to organ preservation, their applicability in developing nations is a topic of much debate. The organ preservation concept was based on the findings of pivotal trials by the Veterans Affairs, European Organization for Research and Treatment of Cancer group and Radiation Therapy Oncology Group. Subsequently numerous studies have been designed to evaluate intensification of treatment as well as study toxicity and tolerability. This review critically analyses current evidence for larynx preservation, experience from various centers on organ preservation strategies as well as applicability of these protocols to developing nations.

Key words

Chemoradiotherapy - clinical protocols - developing countries

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Referenzen

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