Coexisting moyamoya syndrome and type 1 diabetes mellitus: A case report and review of the literature

Nagarjun Bolem; Vincent Nga; Ning Chou; Tseng Yeo; Jeremy Lin; Vijay Sharma

doi:10.4103/ajns.AJNS_218_19

Asian Journal of Neurosurgery, Table of Contents

CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(01): 194-197
DOI: 10.4103/ajns.AJNS_218_19

Case Report

Coexisting moyamoya syndrome and type 1 diabetes mellitus: A case report and review of the literature

Nagarjun Bolem

Division of Neurosurgery, University Surgical Cluster, National University Hospital

,

Vincent Nga

Division of Neurosurgery, University Surgical Cluster, National University Hospital

,

Ning Chou

Division of Neurosurgery, University Surgical Cluster, National University Hospital

,

Tseng Yeo

Division of Neurosurgery, University Surgical Cluster, National University Hospital

,

Jeremy Lin

¹Department of Pediatric Medicine, Division of Pediatric Neurology, National University Hospital

,

Vijay Sharma

²Division of Neurology, YLL School of Medicine, National University Hospital, National University of Singapore

› Author Affiliations

Abstract

Moyamoya disease (MMD) is an incompletely understood malady that affects many age groups, primarily in a bimodal age distribution. We present a patient with the association of type 1 diabetes mellitus (type 1 DM) and MMD followed by a review of the existing literature. We found five papers that describe this association, in the form of one case report, one case series, and three retrospective reviews. Despite a poor understanding of the underlying pathophysiology, a clear association between autoimmune conditions and MMD appears to exist. Clinicians who manage such patients ought to be vigilant and have a high index of suspicion when young patients with type 1 DM present with new onset of neurological symptoms.

Key-words:

Chorea - external carotid–internal carotid bypass - hemiballismus - moyamoya disease - type 1 diabetes mellitus

Full Text

References

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