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DOI: 10.4103/ajns.AJNS_551_20
A rare case of isolated intraventricular primary central nervous system lymphoma in an 85-year-old man

Primary CNS lymphoma (PCNSL) is rare malignant B cell lymphoid tumor of brain which predominantly occurs in supratentorial region in periventricular location. Majority of PCNSL are of DLBCL type and idiopathic in etiology. Here we are reporting a case of primary CNS lymphoma, DLBCL involving extremely uncommon intraventricular location. Central neurocytoma, subependymal giant cell astrocytoma, choroid plexus tumors and meningiomas are the common diagnosis at this site. Aim of reporting this case is to bring awareness of unusual intraventricular location of primary CNS lymphoma which should be kept in mind before considering gross total excision of lesion.
Financial support and sponsorship
Nil.
Publication History
Received: 22 December 2020
Accepted: 11 March 2021
Article published online:
16 August 2022
© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Schlegel U. Primary CNS lymphoma. Ther Adv Neurol Disord 2009;2:93-104.
- 2 Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016 Jun;131:803-20.
- 3 Montesinos-Roengen M, Hans VH, EisHubinger AM, Prinz M. Human Herpes virus is not associated with primary central nervous system lymphoma in HIV negative patients. Acta Neuropathol 2001;102:489-95.
- 4 Deckert M, Engert A, Brück W, Ferreri AJ, Finke J, Illerhaus G, et al. Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma. Leukemia 2011;25:1797-807.
- 5 Korfel A, Weller M, Martus P, Roth P, Klasen HA, Roeth A, et al. Prognostic impact of meningeal dissemination in primary CNS lymphoma (PCNSL): Experience from the G-PCNSL-SG1 trial. Ann Oncol 2012;23:2374-80.
- 6 Küker W, Nägele T, Korfel A, Heckl S, Thiel E, Bamberg M, et al. Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients. J Neurooncol 2005;72:169-77.
- 7 Korfel A, Schlegel U. Diagnosis and treatment of primary CNS lymphoma. Nat Rev Neurol 2013;9:317-27.
- 8 Deckert M, Brunn A, Montesinos-Rongen M, Terreni MR, Ponzoni M. Primary lymphoma of the central nervous system-A diagnostic challenge. Hematol Oncol 2014;32:57-67.