Merkel cell carcinoma is a cutaneous neuroendocrine malignancy that has an aggressive
nature. Classically, it affects the elderly Caucasian population with a predilection
for the sun-exposed areas of the body. Pathogenesis has been linked to ultraviolet
radiation, immunosuppression, and the Merkel cell polyomavirus. Definitive diagnosis
entails histologic evaluation and immunohistochemical staining. With its generalized
appearance and tendency for metastasis, a high index of suspicion must be utilized.
In this case, we present the unique presentation of Merkel cell carcinoma as a rapidly
enlarging lymph node with metastatic disease to the spinal column presenting as new-onset
low back and radicular pain.
Key-words:
Elderly - merkel cell carcinoma - spinal metastasis