Abstract
Leiomyosarcoma is an extremely uncommon subtype of breast sarcoma, with <50 cases
reported in the English literature till date. Patients usually present at an early
stage and follow an indolent course. We reported an unusual case of leiomyosarcoma
of breast in a post -menopausal female,presented with right side breast lump and pain
right side hip. Histomorphological evaluation and immunohistochemistry confirmed the
diagnosis. The patient received palliative radiotherapy 20 Gy in 5 fractions to right
iliac bone and was started on chemotherapycomprising of docetaxel and epirubicin.
Leiomyosarcoma of breast is known to have local recurrence and hematogenous metastasis,
usually 10–15 years after the primary diagnosis. Aggressive behavior of leiomyosarcomas
in the form of such a rapidly growing, fungating mass of 15 cm in greatest dimension
with hematogenous metastasis at the time of initial presentation, as seen in our case,
is extremely unusual.
Keywords
Aggressive - breast - leiomyosarcoma - metastasis
