Abstract
Background: Teratoma refers to neoplasm containing at least two germ cell layers derivatives
foreign to the site of origin. Sacrococcygeal teratoma is most common congenital tumor
commonly present as an exophytic mass of varying size at coccyx. Aims and Objectives: (1) The aim is to find age, sex, and clinical presentation of cases of sacrococcygeal
teratoma. (2) Application of American Academy of Pediatrics' surgical section classification
and histological grading in all cases. Materials and Methods: A retrospective, observational study was conducted in the Department of Pathology
in collaboration with the Department of Pediatric Surgery from February 2009 to January
2014. A total 13 cases of sacrococcygeal teratoma were included in the present study.
The records of these patients were reviewed, and clinical profiles were noted. An
average 12 slides were examined in each case to evaluate histological type and grades.
Results: A retrospective study was conducted including thirteen cases of histologically confirmed
sacrococcygeal teratoma over 5 years period. Male to female ratio was 1:2. As per
as age distribution is concerned, 3 neonates (23%) presented with sacrococcygeal mass.
Associated congenital malformation was seen in 2 cases (15.4%). According to the American
Academy of Pediatrics (Altman's) classification, 23% of cases were Type I, 31% of
cases patients Type II, 31% of cases Type III and 15% were for Type IV. The significant
presacral component was noted in all malignant tumors. Conclusion: Two clinical patterns were observed in sacrococcygeal teratoma related to the age
of presentation. As sacrococcygeal teratoma has potential to become malignant, meticulous
search for the malignant component is required for histopathological categorization.
Keywords
Neuroepithelium - sacrococcygeal teratoma - Totipotential cell
