Indian Journal of Medical and Paediatric Oncology, Table of Contents CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(05): 733-734DOI: 10.4103/ijmpo.ijmpo_275_20 Report on International Publication Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease: A Giant Leap -To Start with Baby Steps Suvir Singh Department of Clinical Haematology and Stem Cell Transplantation, Dayanand Medical College, Ludhiana, Punjab, India › Author AffiliationsRecommend Article Abstract Full Text References References 1 Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R. et al. Ruxolitinib for glucocorticoid-refractory acute graft-versus-host disease. N Engl J Med 2020; 382: 1800-10 2 Malard F, Huang XJ, Sim JPY. Treatment and unmet needs in steroid-refractory acute graft-versus-host disease. Leukemia 2020; 34: 1229-40 3 Schmidt-Hieber M, Fietz T, Knauf W, Uharek L, Hopfenmüller W, Thiel E. et al. Efficacy of the interleukin-2 receptor antagonist basiliximab in steroid-refractory acute graft-versus-host disease. Br J Haematol 2005; 130: 568-74 4 Bordigoni P, Dimicoli S, Clement L, Baumann C, Salmon A, Witz F. et al. Daclizumab, an efficient treatment for steroid-refractory acute graft-versus-host disease. Br J Haematol 2006; 135: 382-5 5 Nassar A, Elgohary G, Elhassan T, Nurgat Z, Mohamed SY, Aljurf M. Methotrexate for the treatment of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. J Transplant 2014; 2014: 980301 6 Bolaños-Meade J, Logan BR, Alousi AM, Antin JH, Barowski K, Carter SL. et al. Phase 3 clinical trial of steroids/mycophenolate mofetil vs steroids/placebo as therapy for acute GVHD: BMT CTN 0802. Blood 2014; 124: 3221-7 7 van der Meij BS, Wierdsma NJ, Janssen JJ, Deutz NE, Visser OJ. If the gut works, use it! But does the gut work in gastrointestinal GvHD?. Bone Marrow Transplant 2017; 52: 466-9 8 Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF. et al. Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: Results of a median 2-year follow-up of COMFORT-I. Haematologica 2013; 98: 1865-71 9 Guttman Y, Nudel A, Kerem Z. Polymorphism in cytochrome P450 3A4 is ethnicity related. Front Genet 2019; 10: 224
