Stauffer’s Syndrome: A Rare Paraneoplastic Syndrome with Renal Cell Carcinoma

Mayank Jain; Joy Varghese; K M Muruganandham; Jayanthi Venkataraman

doi:10.4103/ijmpo.ijmpo_97_17

Indian Journal of Medical and Paediatric Oncology, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(04): 546-547
DOI: 10.4103/ijmpo.ijmpo_97_17

Case Report

Stauffer’s Syndrome: A Rare Paraneoplastic Syndrome with Renal Cell Carcinoma

Autoren

Mayank Jain

Departments of Gastroenterology, Gleneagles global Health City, Chennai, Tamil Nadu, India
Joy Varghese

Departments of Hepatology, Gleneagles global Health City, Chennai, Tamil Nadu, India
K M Muruganandham

Departments of Urology, Gleneagles global Health City, Chennai, Tamil Nadu, India
Jayanthi Venkataraman

Departments of Gastroenterology, Gleneagles global Health City, Chennai, Tamil Nadu, India

Abstract

An elderly male patient presented with cholestatic jaundice and weight loss. On evaluation, he was found to have left renal mass and hepatomegaly. Diagnosis of Stauffer’s syndrome was confirmed based on his clinical history, biochemical evaluation, and liver biopsy. Resolution of jaundice was noted after removal of the renal mass.

Keywords

Cholestasis - jaundice - paraneoplastic - renal

Volltext

Referenzen

References
1 Sharara AI, Panella TJ, Fitz JG. Paraneoplastic hepatopathy associated with soft tissue sarcoma. Gastroenterology 1992; 103: 330-2
2 Karakolios A, Kasapis C, Kallinikidis T, Kalpidis P, Grigoriadis N. Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. Clin Gastroenterol Hepatol 2003; 1: 480-3
3 Saintigny P, Spano JP, Tcherakian F, Pailler MC, Breau JL. Non-metastatic intrahepatic cholestasis associated with bronchial adenocarcinoma. Ann Med Interne (Paris) 2003; 154: 171-5
4 Morla D, Alazemi S, Lichtstein D. Stauffer’s syndrome variant with cholestatic jaundice: A case report. J Gen Intern Med 2006; 21: C11-3
5 Dourakis SP, Sinani C, Deutsch M, Dimitriadou E, Hadziyannis SJ. Cholestatic jaundice as a paraneoplastic manifestation of renal cell carcinoma. Eur J Gastroenterol Hepatol 1997; 9: 311-4
6 Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E. et al. Cancer statistics, 2004. CA Cancer J Clin 2004; 54: 8-29
7 Gold PJ, Fefer A, Thompson JA. Paraneoplastic manifestations of renal cell carcinoma. Semin Urol Oncol 1996; 14: 216-22
8 Stauffer MH. Nephrogenic hepatomegaly. Gastroenterology 1961; 40: 694
9 Blay JY, Rossi JF, Wijdenes J, Menetrier-Caux C, Schemann S, Négrier S. et al. Role of interleukin-6 in the paraneoplastic inflammatory syndrome associated with renal-cell carcinoma. Int J Cancer 1997; 72: 424-30