Abstract
5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has
been approved for the treatment of various cancers. It is associated with systemic
side-effects such as gastrointestinal problems, neutropenia. 5-FU-related encephalopathy
is very rarely reported. Imaging with computed tomography (CT) and magnetic resonance
imaging (MRI) plays a key role in diagnosing and monitoring the changes. Since the
prognosis of cerebral involvement is usually good if recognized and treated in time,
the reporting radiologist and treating physician should be familiar with them. We
present a rare case of 5-FU-induced encephalopathy that was diagnosed based on her
clinical and MRI findings and managed successfully.
Keywords
Chemotherapy - drug-induced encephalopathy - encephalopathy - 5-fluorouracil
