Comparison of gastric motility in patients of type 2 diabetes mellitus with various degrees of glycemic control

Sanchay Jain; Vandana Dhingra; Ravi Kant; Ranjeeta Kumari

doi:10.4103/wjnm.WJNM_112_20

World Journal of Nuclear Medicine, Table of Contents

CC BY-NC-ND 4.0 · World J Nucl Med 2021; 20(04): 336-341
DOI: 10.4103/wjnm.WJNM_112_20

Original Article

Comparison of gastric motility in patients of type 2 diabetes mellitus with various degrees of glycemic control

Authors

Sanchay Jain

Department of Nuclear Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Vandana Dhingra

Department of Nuclear Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Ravi Kant

¹Department of General Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Ranjeeta Kumari

²Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

Abstract

The aim of this study was to evaluate the effect of glycemic control as estimated by glycated hemoglobin A1c (HbA1c) on gastric emptying in patients with type 2 diabetes mellitus (DM) using gastric emptying scintigraphy (GES). This was a cross-sectional study conducted at a tertiary health care center in Northern India. The study included 44 patients who underwent GES using a radiolabeled solid Idli meal containing 1 mCi of Tc-99 m Sulfur Colloid. Patients were divided into three groups based on glycemic control as Group A, B, and C with HbA1c <7%, 7%–9%, and >9%. Statistical analysis was performed using the IBM® SPSS® Statistics Version 23.0 The comparison of proportions was done using the Chi-square test and Fisher's exact test. Means were compared using the independent t-test and one-way analysis of variance. P < 0.05 was considered statistically significant. No statistically significant correlation was found between delayed gastric emptying and glycemic control (P = 0.09), gender (P = 0.228), dietary patterns (P = 0.91), symptoms of gastroparesis (P = 0.06), body mass index (BMI) (P = 0.267), and duration of type 2 DM (P = 0.565). No statistically significant association was also found between glycemic control and time taken for half gastric emptying (t1/2) (P = 0.225). Scintigraphy using Tc-^99m Sulfur Colloid radiolabeled Idli meal can be effectively used for the assessment of gastric emptying. There is no significant correlation of delayed gastric emptying with glycemic control, gender, BMI, type of diet, and duration of diabetes mellitus.

Keywords

Diabetic gastroparesis - gastric emptying scintigraphy - hemoglobin A1c

Full Text

References

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