Background Xanthelasma palpebrarum (XP) is a benign disorder manifesting as yellowish cholesterol-laden
plaques on the eyelids. This paper presents the outcomes in patients with XP who have
undergone surgical excision as the main modality of treatment.
Methods A retrospective review of patients who received surgery for xanthelasma palpebrarum
from March 2007 to March 2011 was conducted. Patients were classified into four grades
according to the location and extent of the lesion, with grade I being the mildest
and grade IV being the most diffuse. Simple excision was performed in grade I and
II lesions, while local flaps and skin grafts were performed in the more advanced
grades.
Results Ninety-five cases from March 2007 to March 2011 were included in this study. 66
cases (70%), were treated by simple excision. Twenty-four cases (25%) and 5 cases
(5%) were treated by simple excision in combination with or without local flaps and
skin grafts. In approximately 1/4 of the patients, orbicularis oris muscle involvement
was observed. 4 patients (4.2%) developed scar contracture postoperatively, which
required a secondary procedure. Recurrence was reported in 3 patients (3.1%). Otherwise.
There were no other reports of major complications or disfigurement.
Conclusions We found that for lesions involving the deep dermis and/or muscle, surgical excision
was the most appropriate therapeutic option.
Keywords
Xanthomatosis - Foam cells - Reconstructive surgical procedures - Eyelids
