CC BY-NC 4.0 · Arch Plast Surg 2015; 42(05): 608-613
DOI: 10.5999/aps.2015.42.5.608
Original Article

Comparison of Clinical and Functional Outcomes Using Pectoralis Major and Cutaneous Free Flaps for Hypopharyngeal Squamous Cell Carcinoma

Taeyul Lee
Department of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, Korea
,
Chulhoon Chung
Department of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, Korea
,
Yongjoon Chang
Department of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, Korea
,
Jaehyun Kim
Department of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, Korea
› Author Affiliations

Background The purpose of this study was to compare postoperative morbidities and functional outcomes of pectoralis major myocutaneous (PMMC) flap and cutaneous free flap reconstruction approaches in hypopharyngeal squamous cell carcinoma patients.

Methods We retrospectively reviewed records from 99 patients who underwent hypopharyngeal reconstruction with a cutaneous free flap (n=85) or PMMC flap (n=14) between 1995 and 2013. Morbidity was classified into hospitalization, medical, or flap-related complications. Functional outcomes were classified into oral re-alimentation and decannulation time.

Results The overall flap-related complication rate was higher in the PMMC flap group (n=8, 57.1%; P=0.019), but the medical morbidity rate was higher in the cutaneous free flap group (n=68, 80%; P=0.006). The rate of pneumonia was higher in the cutaneous free flap group (n=48, 56.5%; P=0.020). Pulmonary premorbidity was the variable most significantly associated with pneumonia (odds ratio=3.012, P=0.012). There was no statistically significant difference in oral re-alimentation and decannulation time between the two groups.

Conclusions Although the functional superiority of free flaps has been reported in many studies, our results do not support this hypothesis. One limitation of our study is the relatively smaller flap size and fewer PMMC flap cases compared with the cutaneous free flap group. The low postoperative medical morbidity incidence rate in the PMMC flap group was clinically significant; however, the free flap group had more flap-related complications. Thus, PMMC flaps should be considered a viable option, especially for patients with pulmonary premorbidities.



Publication History

Received: 30 March 2015

Accepted: 23 June 2015

Article published online:
05 May 2022

© 2015. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

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  • References

  • 1 Bianchi B, Ferri A, Ferrari S. et al. The free anterolateral thigh musculocutaneous flap for head and neck reconstruction: one surgeon's experience in 92 cases. Microsurgery 2012; 32: 87-95
  • 2 Chepeha DB, Annich G, Pynnonen MA. et al. Pectoralis major myocutaneous flap vs revascularized free tissue transfer: complications, gastrostomy tube dependence, and hospitalization. Arch Otolaryngol Head Neck Surg 2004; 130: 181-186
  • 3 Piazza C, Taglietti V, Nicolai P. Reconstructive options after total laryngectomy with subtotal or circumferential hypopharyngectomy and cervical esophagectomy. Curr Opin Otolaryngol Head Neck Surg 2012; 20: 77-88
  • 4 Welkoborsky HJ, Deichmuller C, Bauer L. et al. Reconstruction of large pharyngeal defects with microvascular free flaps and myocutaneous pedicled flaps. Curr Opin Otolaryngol Head Neck Surg 2013; 21: 318-327
  • 5 Song HG, Yun IS, Lee WJ. et al. Robot-assisted free flap in head and neck reconstruction. Arch Plast Surg 2013; 40: 353-358
  • 6 You YS, Chung CH, Chang YJ. et al. Analysis of 120 pectoralis major flaps for head and neck reconstruction. Arch Plast Surg 2012; 39: 522-527
  • 7 Corten EM, Schellekens PP, Hage JJ. et al. Clinical outcome after pedicled segmental pectoralis major island flaps for head and neck reconstruction. Ann Plast Surg 2009; 63: 292-296
  • 8 Cristalli G, Pellini R, Roselli R. et al. Pectoralis major myocutaneous flap for hypopharyngeal reconstruction: long-term results. J Craniofac Surg 2011; 22: 581-584
  • 9 McLean JN, Carlson GW, Losken A. The pectoralis major myocutaneous flap revisited: a reliable technique for head and neck reconstruction. Ann Plast Surg 2010; 64: 570-573
  • 10 Ariyan S. The pectoralis major myocutaneous flap: a versatile flap for reconstruction in the head and neck. Plast Reconstr Surg 1979; 63: 73-81
  • 11 Yang GF, Chen PJ, Gao YZ. et al. Forearm free skin flap transplantation: a report of 56 cases. 1981. Br J Plast Surg 1997; 50: 162-165
  • 12 Lim YS, Kim JS, Kim NG. et al. Free flap reconstruction of head and neck defects after oncologic ablation: one surgeon's outcomes in 42 cases. Arch Plast Surg 2014; 41: 148-152
  • 13 Bozikov K, Arnez ZM. Factors predicting free flap complications in head and neck reconstruction. J Plast Reconstr Aesthet Surg 2006; 59: 737-742
  • 14 Bianchi B, Copelli C, Ferrari S. et al. Free flaps: outcomes and complications in head and neck reconstructions. J Craniomaxillofac Surg 2009; 37: 438-442
  • 15 O'Neill JP, Shine N, Eadie PA. et al. Free tissue transfer versus pedicled flap reconstruction of head and neck malignancy defects. Ir J Med Sci 2010; 179: 337-343
  • 16 Shestak KC, Jones NF. Microsurgical free-tissue transfer in the elderly patient. Plast Reconstr Surg 1991; 88: 259-263
  • 17 Chick LR, Walton RL, Reus W. et al. Free flaps in the elderly. Plast Reconstr Surg 1992; 90: 87-94
  • 18 Joo YH, Cho KJ, Park JO. et al. Role of larynx-preserving partial hypopharyngectomy with and without postoperative radiotherapy for squamous cell carcinoma of the hypopharynx. Oral Oncol 2012; 48: 168-172