zeitschrift für gastroenterologie
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D'Alessandro, LA
Dissection TNFα/NF-κB signalling in murine hepatocytes–a model for the priming phase of liver regeneration
Daehn, C
Application of upcyte® technology to primary cells for developing alternatives to current in vitro metabolism models
Dähn, C
Characterization of liver specific functions of upcyte® hepatocytes grown in 3D and co-cultured with upcyte® endothelial cells
Damm, G
Chemotherapeutic use of Resveratrol on liver cancer cell lines cause damage on primary human hepatocytes
Comparison of two size variants of a miniaturized multi-compartment three-dimensional (3D)-bioreactor system for primary human hepatocyte cultivation
Genistein shows beneficial effects on hepatic lipid metabolism in an in vitro hepatic steatosis model
Soy isoflavone Genistein affects energy metabolism in a steatotic liver model
Dandri, M
TREATMENT WITH PEGYLATED INTERFERON-ALPHA INDUCES SUSTAINED SUPPRESSION OF BOTH VIRUS REPLICATION AND ANTIGENEMIA IN HUMANIZED uPA/SCID MICE STABLY INFECTED WITH HBV
Selective induction of apoptosis by HMG-CoA-reductase inhibitors in hepatoma cells is dependent on p53 expression
PRETREATMENT OF HUMANIZED uPA/SCID MICE WITH INTERFERON ALPHA STRONGLY INHIBITS THE ESTABLISHMENT OF HBV INFECTION
Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication
THE ENTRY INHIBITOR MYRCLUDEX-B EFFICIENTLY BLOCKS VIRAL SPREADING IN VIVO IN HUMAN LIVER CHIMERIC uPA/ SCID MICE PREVIOUSLY INFECTED WITH HEPATITIS B VIRUS
HDV LACKING HBV CAN INFECT HUMAN HEPATOCYTES IN THE LIVER OF CHIMERIC uPA/SCID MICE AND PERSIST FOR AT LEAST SIX WEEKS BEFORE BEING RESCUED BY SUPERINFECTION WITH HBV
Darnell, M
Characteristics of human non-cirrhotic and cirrhotic liver sections in a novel ex vivo perfusion system
Dauch, D
In vivo RNAi screening to genetically dissect malignant progression from hepatocytes harboring constitutive active AKT–1
Dayoub, R
Gallensäuren induzieren die Expression von ALR, einem Leberregeneration assoziierten Faktor
De Backer, K
Bioavailability of the HCV NS3/4A Protease Inhibitor Telaprevir–Effect of Different Types of Food
Debey-Pascher, S
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
Dechêne, A
Die Mini-Laparoskopie ist sicher und zeigt eine hohe Inzidenz akuter Fibrosebildung bei Patienten mit akutem Leberversagen
Decker, G
Beschleunigtes Tumorwachstum des spontanen Hepatozellulären Karzinoms (HCC) in fibrotischer/zirrhotischer Leber im Mausmodell
Delogu, S
Die Ko-Aktivierung von AKT and N-Ras in der Mäuseleber führt zu einer raschen Hepatokarzinogenese, vermittelt über mTORC1, FOXM1/SKP2 und c-Myc
HSF1 ist ein Effektor der Onkogene Ras und AKT und trägt zur Entstehung und Progression des Hepatozellulären Karzinoms bei
De Murtas, V
HSF1 ist ein Effektor der Onkogene Ras und AKT und trägt zur Entstehung und Progression des Hepatozellulären Karzinoms bei
Die Dysregulation des Zellmetabolismus, hervorgerufen durch AKT, trägt zur Entstehung der Insulin-induzierten Hepatokarzinogenese bei und lässt sich effektiv durch Gabe des dualen PI3K/mTOR Inhibitors NVP-BEZ235 zurückführen
Denk, G
Die Serum-Apoptosemarker sICAM und sFAS sind bei autoimmunen Lebererkrankungen erhöht und korrelieren mit der Höhe der Serumleberwerte
De Paepe, E
Bioavailability of the HCV NS3/4A Protease Inhibitor Telaprevir–Effect of Different Types of Food
Deray, G
Telbivudine treatment improves renal function of Chronic Hepatitis B (CHB) patients
Destefanis, G
Die Ko-Aktivierung von AKT and N-Ras in der Mäuseleber führt zu einer raschen Hepatokarzinogenese, vermittelt über mTORC1, FOXM1/SKP2 und c-Myc
HSF1 ist ein Effektor der Onkogene Ras und AKT und trägt zur Entstehung und Progression des Hepatozellulären Karzinoms bei
Die Dysregulation des Zellmetabolismus, hervorgerufen durch AKT, trägt zur Entstehung der Insulin-induzierten Hepatokarzinogenese bei und lässt sich effektiv durch Gabe des dualen PI3K/mTOR Inhibitors NVP-BEZ235 zurückführen
Deterding, K
Unexpected increase of Hepatitis B Surface Antigen (HBsAg) levels during treatment with nucleos(t)ide analogous 12–24 months before virological breakthrough and resistance
Early versus delayed treatment of acute hepatitis C: Final results of the randomized controlled German HEP-NET acute HCV-III study
De Toni, EN
Antitumor efficacy of the c-met inhibitor tivantinib (ARQ–197) in liver cancer cells: effects on apoptosis and cell cycle
Dettmer, K
Downregulation of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease promotes hepatic inflammation and fibrosis
Diehl, L
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance to systemic circulating carcinoembryonic antigen: A new mechanism of Tumour-immune-Suppression
Dienes, HP
Sekretionsprofile extrazellulärer miRNA nach myofibroblastischer Transdifferenzierung Hepatischer Sternzellen: Neue Biomarker der Fibrose?
Identifizierung von neuen microRNA-Zieldomänen während der myofibroblastischen Transdifferenzierung von hepatischen Sternzellen durch "Next Generation Sequencing"
TGF-beta mediates transcriptional repression of miR–29 a/b1 during liver fibrosis
The loss of miR–198 is crucial for development and progression of hepatocellular carcinoma
miR–101 im komplexen Zusammenspiel von Steatose und Steatohepatitis bei Nicht-Alkoholischen Fettlebererkrankungen
Diepolder, H
Early versus delayed treatment of acute hepatitis C: Final results of the randomized controlled German HEP-NET acute HCV-III study
Dietrich, C
Liver stiffness in cardiac insufficiency: Is elevated GGT due to cardiac cirrhosis?
Dietze, O
Expression pattern of stem cell markers in a tissue microarray of human biliary tract cancer
Di Fazio, P
Induction of endoplasmic reticulum-mediated stress pathways in liver cancer cell lines after overexpression of Hepatitis B virus envelope proteins
Panobinostat treatment determines oncogenic miRNAs down-regulation in liver cancer cells
Dollinger, M
The presence of esophageal varices (EV), but not treatment with beta-blockers, is associated with a poorer survival in patients with cirrhosis and ascites
Combination Treatment of Sorafenib and Resminostat, a new HDAC Inhibitor, in Patients with Sorafenib-resistant Hepatocellular Carcinoma (HCC) – Results of the Dose-Escalation Phase
MSCs augment liver regeneration after paracetamol-induced acute liver injury by their anti-apoptotic and pro-proliferative mode of action
Dombrowski, F
Die Ko-Aktivierung von AKT and N-Ras in der Mäuseleber führt zu einer raschen Hepatokarzinogenese, vermittelt über mTORC1, FOXM1/SKP2 und c-Myc
HSF1 ist ein Effektor der Onkogene Ras und AKT und trägt zur Entstehung und Progression des Hepatozellulären Karzinoms bei
Die Dysregulation des Zellmetabolismus, hervorgerufen durch AKT, trägt zur Entstehung der Insulin-induzierten Hepatokarzinogenese bei und lässt sich effektiv durch Gabe des dualen PI3K/mTOR Inhibitors NVP-BEZ235 zurückführen
The transcriptional regulator YAP induces Notch-pathway activity in hepatocytes and hepatocellular carcinoma cells
Klarzellige Herde veränderter Hepatozyten der menschlichen Leber zeigen eine Überexpression der protoonkogenen Signalwege AKT/mTOR und Ras/Raf1 sowie einen lipogenen Phänotyp (analog dem Hyperinsulinämie-induzierten Hepatokarzinogenese-Modell der Ratte und hepatozellulären Karzinomen beim Menschen)
Dong, Y
Direkter Vergleich der Hepatitis B Viruskinetik während 12 Wochen mit Telbivudine (LDT) vs. Tenofovir (TDF) vs. Kombination LDT und TDF bei Patienten mit chronischer Hepatitis B
Telbivudine treatment improves renal function of Chronic Hepatitis B (CHB) patients
Dooley, S
IFN-gamma inhibits hepatic progenitor cell activation in patients with chronic hepatitis B and in mice
Extracellular matrix induced signaling and TGF-β regulate Caveolin–1 expression in hepatocytes
Mapping differential susceptibility of primary hepatocytes to TGF-β in the BXD population of recombinant inbred mouse lines
Cultivation of primary hepatocytes induces an inflammation-cholestasis response that resembles features of in vivo inflammation during damage and regeneration
TGF-beta induced hepatocellular Wisp1 is expressed in hepatocellular carcinoma and drives proliferation of epithelial-type cancer cells
TGF-β1 contributes to intrahepatic cholangiocarcinoma via Smad dependent and independent pathways
Dll4 plays a critical role in HBV-associated liver fibrogenesis
Loss of the TGF-β cytostatic response in liver cancer cells correlates with a reduced Smad3 activation
Smad7 expression is upregulated in HCC patients and correlates with Smad2 mediated downstream signaling in HCC cell lines
Neutralization of Bone Morphogenetic Protein (BMP)–9 in mouse liver reduces CCl–4 mediated fibrogenesis
Impact of HBV infection on TGF-β signaling in primary human hepatocytes
HCV core protein interferes with Smad1 and Smad3 dependent TGF-β signaling in HCC cells
Dorn, C
Atrophin 2 expression in chronic liver disease functionally affects activated hepatic stellate cells
Expression of the atypical cadherin Fat1 in hepatic fibrosis
MMP–9 activity is increased by adiponectin in primary human hepatocytes but negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis
Aging promotes hepatocellular steatosis, inflammation and fibrosis in non-alcoholic steatohepatitis in mice
The Role of PI3K p110gamma in chronic liver injury
Enhanced TLR4 expression in steatotic hepatocytes
Xanthohumol suppresses hepatic inflammatory response to warm ischemia-reperfusion injury
BMP6 protects against hepatic inflammation and fibrosis in experimental NASH models
Downregulation of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease promotes hepatic inflammation and fibrosis
Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis
Increased expression of the glucose transporter GLUT1 in liver fibrosis
Xanthohumol improves glucose tolerance and inhibits hepatic steatosis, inflammation and fibrogenesis in a murine model of non-alcoholic steatohepatitis
Gallensäuren induzieren die Expression von ALR, einem Leberregeneration assoziierten Faktor
Xanthohumol inhibits hepatitis B virus replication in vitro
Dostert, K
The Role of PI3K p110gamma in chronic liver injury
Enhanced TLR4 expression in steatotic hepatocytes
Drebber, U
miR–101 im komplexen Zusammenspiel von Steatose und Steatohepatitis bei Nicht-Alkoholischen Fettlebererkrankungen
Drognitz, O
Naturally occurring, tumor-specific CD8+ T cells in patients with hepatocellular carcinoma display a clear immunodominance
Drvarov, O
JNK1 is protective for the progression of NEMO-dependent hepatitis
Dückers, H
Prospektive diagnostische und prognostische Evaluation der transienten Leberelastographie bei kritisch kranken Patienten auf einer internistischen Intensivstation
Dudas, J
Lactoferrin gene expression upregulation in liver during turpentine oil- or bacterial LPS-induced acute phase reaction
Dufour, JF
Age above 60 years is not a negative predictive factor for combined antiviral therapy with pegylated interferon alpha and ribavirin in hepatitis C patients
Dzieran, J
Extracellular matrix induced signaling and TGF-β regulate Caveolin–1 expression in hepatocytes
Loss of the TGF-β cytostatic response in liver cancer cells correlates with a reduced Smad3 activation
Smad7 expression is upregulated in HCC patients and correlates with Smad2 mediated downstream signaling in HCC cell lines
HCV core protein interferes with Smad1 and Smad3 dependent TGF-β signaling in HCC cells