zeitschrift für gastroenterologie
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Sahin, H
The CXCR3 ligand CXCL9 attenuates neoangiogenesis and liver fibrosis in vivo
G-Protein-Rezeptor abhängige Immunmodulation durch Induktion der KC Expression (murines CXCL8/IL–8 Homolog) in murinen hepatischen Sternzellen nach Stimulation mit CXCL9
Sales, S
Charakterisierung der Smo-KO-induzierten Steatose in der Leber mittels Shotgun-Lipidomanalyse
Sallmon, H
The significance of appropriate controls in surgical microRNA studies of the liver
Salnikova, O
Influence of IL–1β and IL–1 receptor antagonist on T-cell adhesion to hepatic endothelial cells: a potential implication for leukocyte recruitment in HCC
Sandig, C
Analysis of the cytokine response in a mouse model of liver ischemia / reperfusion injury
Saner, F
Serum sodium based modification of the MELD score does not improve the predictive value in acute liver failure
Sarrazin, C
Variants in the human PPIA gene render host cells refractory to hepatitis C virus infection by destabilization of the essential host factor cyclophilin A
Sass, G
Nitric oxide supports carbon monoxide-induced protection from apoptosis in isolated primary mouse hepatocytes
Essential role of Sharpin in TNFα dependent NFκB activation in primary hepatocytes
Induction of heme oxygenase 1 in Mdr2ko mice reduces hepatic inflammation, prevents fibrosis progression and supports fibrolysis
Selective induction of apoptosis by HMG-CoA-reductase inhibitors in hepatoma cells is dependent on p53 expression
Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication
Sauer, IM
The significance of appropriate controls in surgical microRNA studies of the liver
Sauer, P
Concomitant immunological diseases in primary sclerosing cholangitis are a risk factor for reduced survival
Sauerbruch, T
Beschleunigtes Tumorwachstum des spontanen Hepatozellulären Karzinoms (HCC) in fibrotischer/zirrhotischer Leber im Mausmodell
Analysis of cellular origin and degradation pathways of the endocannabinoid 2-arachidonoyl glycerol during liver fibrogenesis
Ribavirin beeinflusst unterschiedlich die Funktionen von CD4+ TH1-, TH2- und regulatoischen T-Zell-Klonen bei chronischer Hepatitis C
Das CXCL1 rs4074 A Allel führt nach TLR2 Stimulation zu einer verstärkten CXCL1 Expression und ist ein Risikofaktor für Zirrhose bei HCV Genotype 1-infizierten Patienten
Toxische Leberschädigung führt im Mausmodell zu einem vermehrten Einwandern von Endothelzellen und endothelialen Vorläuferzellen
Rolle der Janus-Kinase 2 (Jak2) bei der AT1-Rezeptor-vermittelten hepatischen Fibrose
Renin-überexprimierende Ratten, ein genetisches Tiermodell zur spontanen Fibrose und portalen Hypertension
Der AT1-Rezeptor reguliert die Expression der Renin-Angiotensin-Systen(RAS)-Komponenten in der Fibrose
HSC gezielte Hemmung der Rho-kinase senkt den Portaldruck mit geringen systemischen Nebenwirkungen
Signature of three novel surrogate markers predicts liver stiffness and fibrosis stages in a cohort of patients with chronic liver disease
Jak–2 Hemmung senkt den Pfortaderdruck bei der Leberzirrhose
Atorvastatin vermindert die Proliferation und Apoptose in hepatischen Sternzellen durch die Seneszenz Induktion
Die Gabe von Nexavar beeinflusst in hypoxischen Cholangiokarzinomzellen das Zellüberleben
Einfluss der HFE-Varianten C282Y und H63D auf das genetische Risiko bösartiger Gallenwegserkrankungen: potentielle Modulation durch H63D-Homozygotie
Der NKp46-Rezeptor ist an der Regulation der anti-fibrotischen Aktivität von NK Zellen beteiligt
Adaptive CD4+ regulatorische T-Zellen regulieren die Fibrogenese durch Produktion von IL–8 bei chronischer Hepatitis C
Der CYP27B1–1260 Promoter Polymorphismus rs120877012 ist bei HCV/HIV koinfizierten Patienten signifikant mit einem Ansprechen auf die Therapie der Hepatitis C Erkrankung (SVR) assoziiert
Gestörte Funktion von CD56high CXCR3(+) NK Zellen als möglicher neuer Mechanismus der HCV-assoziierten Leberfibrose
HCV-vermittelte Blockierung der IL–2 Sekretion von CD4(+) T-Zellen hemmt die anti-fibrotische Aktivität von NK-Zellen
Saugspier, M
Expression of the atypical cadherin Fat1 in hepatic fibrosis
Aging promotes hepatocellular steatosis, inflammation and fibrosis in non-alcoholic steatohepatitis in mice
The Role of PI3K p110gamma in chronic liver injury
BMP6 protects against hepatic inflammation and fibrosis in experimental NASH models
Downregulation of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease promotes hepatic inflammation and fibrosis
Increased expression of the glucose transporter GLUT1 in liver fibrosis
Hop bitter acids inhibit PD-L1 expression and tumorigenicity of hepatocellular carcinoma cells
In vitro and in vivo models for chemotherapy-associated steatohepatitis reveal an effect of irinotecan on fatty acid binding protein expression
Schadmand-Fischer, S
IgG4-related sclerosing cholangitis mimicking cholangiocellular carcinoma in a patient with obstructive jaundice
Schäffler, A
MMP–9 activity is increased by adiponectin in primary human hepatocytes but negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis
Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver
Schaller, M
Novel treatment approach for therapy of peritoneal carcinosis using Vaccinia virotherapeutics
Schanze, N
Schlüsselrolle von PGE2 im Circulus vitiosus der Prostaglandin- und Cytokin-vermittelten hepatischen Insulinresistenz
Scharfenberg, A
Valide nicht-invasive Diagnostik einer Leberzirrhose durch Messung der maximalen Leberfunktionskapazität mittels LiMAx-Test
Schattenberg, JM
Hepatozelluläres Karzinom (HCC) bei NASH – Trend zur Metastasierung?
Schelcher, C
Human augmenter of liver regeneration could have a potential protective role in an alcohol-induced toxicity model
Scheller, K
Characterization of liver specific functions of upcyte® hepatocytes grown in 3D and co-cultured with upcyte® endothelial cells
Application of upcyte® technology to primary cells for developing alternatives to current in vitro metabolism models
Schemmer, P
Methylation profiling combined with genomic and transcriptomic data points out to new tumor suppressor genes in human hepatocarcinogenesis
Analysis of the cytokine response in a mouse model of liver ischemia / reperfusion injury
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma
Schenk, M
Specific therapeutic targeting of liver malignancies by transient depletion of adenosine tri-phosphates
Scherbaum, N
The proapoptotic protein Bim is not differentially regulated in CD8+ T cells from resolved or chronic HCV infection
Scherer, MN
Weniger als 10% der Patienten mit einem Hepatozellulären Karzinom kommen für eine Lebertransplantation in Frage und zeigen die besten (Langzeit-) Überlebensraten
Scheulen, ME
Combination Treatment of Sorafenib and Resminostat, a new HDAC Inhibitor, in Patients with Sorafenib-resistant Hepatocellular Carcinoma (HCC) – Results of the Dose-Escalation Phase
Scheurich, C
Charakterisierung von B – Zell – Aktivierungs- und Koinhibitionsmarkern in Patienten mit chronischen Virusinfektionen (HBV; HCV)
Downregulation of CD73 surface expression in regulatory as well as effector T cells in chronic HCV infection
Fine Characterization and Determination of Cross-Reactivity of HCV-specific CD4+ T Cell Epitopes
Schiene-Fischer, C
Variants in the human PPIA gene render host cells refractory to hepatitis C virus infection by destabilization of the essential host factor cyclophilin A
Schierwagen, R
Rolle der Janus-Kinase 2 (Jak2) bei der AT1-Rezeptor-vermittelten hepatischen Fibrose
Der AT1-Rezeptor reguliert die Expression der Renin-Angiotensin-Systen(RAS)-Komponenten in der Fibrose
HSC gezielte Hemmung der Rho-kinase senkt den Portaldruck mit geringen systemischen Nebenwirkungen
Jak–2 Hemmung senkt den Pfortaderdruck bei der Leberzirrhose
Atorvastatin vermindert die Proliferation und Apoptose in hepatischen Sternzellen durch die Seneszenz Induktion
Schievenbusch, S
The protein phosphatase 2A inhibitior I–2PP2A/SET is highly expressed during murine fetal liver development and hepatocarcinogenesis
Schiffelholz, W
The Role of Weight Loss (WL) as On-Tretament Predictive Factor for SVR in the Treatment of Chronic Hepatitis C (CHC) Patients with Peginterferon alfa–2A (PEG) and Ribavirin (RBV)
Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting
Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real Life
Schildberg, F
MHC class I transfer from stellate cells to LSEC allows for sinusoidal immunsurveillance
Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
Schildberg, FA
Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance to systemic circulating carcinoembryonic antigen: A new mechanism of Tumour-immune-Suppression
Schildgen, J
Nitric oxide supports carbon monoxide-induced protection from apoptosis in isolated primary mouse hepatocytes
Schindler, F
Extracellular matrix induced signaling and TGF-β regulate Caveolin–1 expression in hepatocytes
Schirmacher, P
Dissection TNFα/NF-κB signalling in murine hepatocytes–a model for the priming phase of liver regeneration
Methylation profiling combined with genomic and transcriptomic data points out to new tumor suppressor genes in human hepatocarcinogenesis
Concomitant immunological diseases in primary sclerosing cholangitis are a risk factor for reduced survival
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma
Loss of the TGF-β cytostatic response in liver cancer cells correlates with a reduced Smad3 activation
Type, Density, and Location of Immune Cells within Cholangiocarcinomas Predict Clinical Outcome
Verstärkung von Tumorentstehung und Progress durch transiente Telomerdysfunktion in Telomerase-profizienten Mäusen
In vivo RNAi screening to genetically dissect malignant progression from hepatocytes harboring constitutive active AKT–1
AKT signaling is involved in protumorigenic function of MDM4 in human hepatocellular carcinoma
A nuclear pore component regulates select p53 target genes
Towards unravelling the molecular mechanisms of human hepatocyte steatosis in situ
The transcriptional regulator YAP induces Notch-pathway activity in hepatocytes and hepatocellular carcinoma cells
Schirmbeck, R
IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
Schlaak, JF
HCV/TLR3 modulated the expression of RANTES in murine activated hepatic stellate cells
Toll-like receptor-activated primary human hepatocytes produce inflammatory cytokines and different types of interferon, resulting in HCV suppression in vitro
Better detection of Hepatocellular Carcinoma by combining Alphafeto-Protein (AFP) and Des-Gamma-Carboxyprothrombin (DCP)
Presence of primary human hepatocytes inhibits expansion of virus-specific CD8+ T cells in vitro
In vivo treatment with nanolipid-formulated siRNAs targeting ISG15 leads to enhanced responsiveness to interferon in primary hepatocytes
Hepatic toll-like receptors can be activated by application of siRNAs in vivo via MyD88-dependent pathways which can be controlled by chemical ribose modifications of the siRNA backbone
All-trans retinoic acid co-administered with pegylated interferon and ribavirin does not influence viral kinetics in hepatitis C infected patients with previous non-response: Results of the ATRACTION study
Schlaphoff, V
HEV-specific T-cell responses are associated with control of HEV infection
Schlattjan, M
Serum sodium based modification of the MELD score does not improve the predictive value in acute liver failure
Bariatric surgery ameliorates NAFLD in morbidly obese patients
miR–101 im komplexen Zusammenspiel von Steatose und Steatohepatitis bei Nicht-Alkoholischen Fettlebererkrankungen
Schleicher, S
Armed oncolytic measles vaccine virus–a novel therapeutic agent for virotherapy of sarcomas of gastrointestinal and non-gastrointestinal origin
Schlitt, HJ
Resection vs. Transplantation as Curative Treatment Options for Hepatocellular Carcinoma in Cirrhosis – Systematic Review
Weniger als 10% der Patienten mit einem Hepatozellulären Karzinom kommen für eine Lebertransplantation in Frage und zeigen die besten (Langzeit-) Überlebensraten
Schlueter, H
Nitric oxide supports carbon monoxide-induced protection from apoptosis in isolated primary mouse hepatocytes
Schmid, S
Weniger als 10% der Patienten mit einem Hepatozellulären Karzinom kommen für eine Lebertransplantation in Frage und zeigen die besten (Langzeit-) Überlebensraten
Schmidt, N
Naturally occurring, tumor-specific CD8+ T cells in patients with hepatocellular carcinoma display a clear immunodominance
Schmidt, RE
Chronic hepatitis E in patients with CVID in Germany?
Schmidt, W
Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting
Schmidt-Heck, W
Cultivation of primary hepatocytes induces an inflammation-cholestasis response that resembles features of in vivo inflammation during damage and regeneration
Schmitt, E
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
Schmitt, J
Intestinal inflammation induces alterations in enterohepatic Fgf15 signalling, changes in hepatic bile acid metabolism and a “toxic bile” composition in DSS-treated mice
Impact of genetic concentrative nucleoside transporter variants on interferon/ribavirin therapy response in hepatitis C patients
Age above 60 years is not a negative predictive factor for combined antiviral therapy with pegylated interferon alpha and ribavirin in hepatitis C patients
Schmitz, G
FATP 4 beeinflusst die Palmitat induzierte Apoptose durch Veränderung des Lipidstoffwechsels
Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) Generates Hepatoprotective conjugated UDCA, Phosphatidylcholine, Medium-chain Fatty acids and Plasmalogen 16: 1
Schmitz, P
The CXCR3 ligand CXCL9 attenuates neoangiogenesis and liver fibrosis in vivo
A functional role of Macrophage Migration Inhibitory Factor (MIF) for liver steatosis in mice by activation of AMP kinase
Schmitz, V
Toxische Leberschädigung führt im Mausmodell zu einem vermehrten Einwandern von Endothelzellen und endothelialen Vorläuferzellen
Die Gabe von Nexavar beeinflusst in hypoxischen Cholangiokarzinomzellen das Zellüberleben
Schneider, B
Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance to systemic circulating carcinoembryonic antigen: A new mechanism of Tumour-immune-Suppression
Schneider, S
IL28B genetic variation and ratio of y-GT/ALT as predictors for virological response in chronic hepatitis C virus genotype 1 infected patients
Schnitzbauer, AA
Resection vs. Transplantation as Curative Treatment Options for Hepatocellular Carcinoma in Cirrhosis – Systematic Review
Weniger als 10% der Patienten mit einem Hepatozellulären Karzinom kommen für eine Lebertransplantation in Frage und zeigen die besten (Langzeit-) Überlebensraten
Schober, A
The Role of Weight Loss (WL) as On-Tretament Predictive Factor for SVR in the Treatment of Chronic Hepatitis C (CHC) Patients with Peginterferon alfa–2A (PEG) and Ribavirin (RBV)
Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting
Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real Life
Scholten, D
G-Protein-Rezeptor abhängige Immunmodulation durch Induktion der KC Expression (murines CXCL8/IL–8 Homolog) in murinen hepatischen Sternzellen nach Stimulation mit CXCL9
Schölzel, K
MHC class I transfer from stellate cells to LSEC allows for sinusoidal immunsurveillance
Schott, E
Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real Life
Schrader, J
Targeting the cytoskeleton inhibits proliferation of hepatoma cells by suppressing mitogenic signalling
Schramm, C
Atypische Präsentation der Primär biliären Zirrhose bei Männern
Zweitlinientherapie der Primär Biliären Zirrhose: Klinische Charakteristika und Therapieindikation–eine retrospektive Analyse
Induction of heme oxygenase 1 in Mdr2ko mice reduces hepatic inflammation, prevents fibrosis progression and supports fibrolysis
Patienten mit Primär Sklerosierender Cholangitis weisen ein gestörtes Gleichgewicht zwischen Foxp3+ regulatorischen T-Zellen und proinflammatorischen Th17 Zellen auf
IgG4-positive plasma cells can be elevated in malignant hepato-biliary and pancreatic diseases and do not allow discrimination between neoplastic and autoimmune disease
IFN-gamma und IL–17 Produktion durch SepSecS-reaktive T Zellen aus Patienten mit Autoimmuner Hepatitis
Schraplau, A
Regulation des Schilddrüsenhormonabbaus durch Mausstamm-spezifische Fasten-abhängige UDP-Glucuronosyltransferase-Induktion
Schreckenbach, T
Leberteilresektionen bei kolorektalen Lebermetastasen–Kein Unterschied im Überleben zwischen R0- und R1-Resektionen
Der Possum Score als prädiktiver Marker für Morbidität und Mortalität in der hepatobiliären Chirurgie
Morbidität und die stationäre Behandlungsdauer bei der elektiven Leberteilresektion: Verbesserungspotentiale durch Fast Track Komponenten?
Schreiter, T
Characteristics of human non-cirrhotic and cirrhotic liver sections in a novel ex vivo perfusion system
Schuchmann, M
Add-on of pegylated interferon alpha–2a (PEG-IFN) triggers antigen-independent TNF-alpha production by CD4+ T cells in patients with pretreated chronic hepatitis B
IgG4-related sclerosing cholangitis mimicking cholangiocellular carcinoma in a patient with obstructive jaundice
Hepatozelluläres Karzinom (HCC) bei NASH – Trend zur Metastasierung?
Hemmung der Makrophagen abhängigen Wachstumsfaktoren durch Sorafenib
All-trans retinoic acid co-administered with pegylated interferon and ribavirin does not influence viral kinetics in hepatitis C infected patients with previous non-response: Results of the ATRACTION study
Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real Life
Schughart, K
Identification of phenotypic and expression quantitative trait loci (p/eQTLs) affecting liver fibrosis by genome-wide association analysis in recombinant inbred mouse lines
Schultheiß, M
Impact of tumor markers in diagnosis of patients with hepatocellular carcinoma (HCC) and their clinicopathologic correlation: an interim analysis
Is Sorafenib an acceptable treatment possibility for patients with advanced hepatocellular carcinoma?
Schultz, F
Expression of prospero-related homeobox 1 (prox–1) transcription factor and epithelial adhesion molecule (EpCAM) in a rat model of intrahepatic cholangiocarcinogenesis
Schultze, JL
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
Adaptive CD4+ regulatorische T-Zellen regulieren die Fibrogenese durch Produktion von IL–8 bei chronischer Hepatitis C
Schulz, R
TIMP–2, Serum-Marker einer portalen Hypertension bei Mukoviszidosepatienten
Schulze, A
Optimization of maturity levels of human hepatic cell lines in tissue culture
Schulze, K
EpCAM-positive zirkulierende Tumorzellen als möglicher prognostischer Biomarker für ein fortgeschrittenes HCC
Schulze-Bergkamen, H
Transkriptionelle und Post-Transkriptionelle Regulation von Mcl–1 durch die p53-Familie
The role of the tumor suppressor CYLD for the proliferation and invasion of hepatocellular carcinoma cells
Schulze zur Wiesch, J
Hepatitis C Therapie in HCV/HIV koinfizierten Patienten – eine monozentrische Kohortenstudie
Charakterisierung von B – Zell – Aktivierungs- und Koinhibitionsmarkern in Patienten mit chronischen Virusinfektionen (HBV; HCV)
Bestimmung des transhepatischen Endotoxin-Gradienten vor und nach Anlage eines transjugulären portosystemischen Shunts (TIPS)
Downregulation of CD73 surface expression in regulatory as well as effector T cells in chronic HCV infection
Chronische Hepatitis C Infektion: Herausforderung Alter
Fine Characterization and Determination of Cross-Reactivity of HCV-specific CD4+ T Cell Epitopes
Schumacher, F
c-met vermeidet die Entwicklung Nicht- Alkoholischer- Fettleberhepatitis (NASH) im Mausmodell
Modulation of hepatic lipid content by Caspase 8 in non-alcoholic steatohepatitis
Schütte, J
A Microfluidic 3D Hepatocyte Culture System -HepaChip®- For Drug And Toxicity Investigations
Schwab, M
Specific therapeutic targeting of liver malignancies by transient depletion of adenosine tri-phosphates
Schwinge, D
Induction of heme oxygenase 1 in Mdr2ko mice reduces hepatic inflammation, prevents fibrosis progression and supports fibrolysis
Schyschka, L
Entrapment of primary human hepatocytes in extracellular matrix gels for long term toxicity studies
Sebode, M
Patienten mit Primär Sklerosierender Cholangitis weisen ein gestörtes Gleichgewicht zwischen Foxp3+ regulatorischen T-Zellen und proinflammatorischen Th17 Zellen auf
IFN-gamma und IL–17 Produktion durch SepSecS-reaktive T Zellen aus Patienten mit Autoimmuner Hepatitis
Seehofer, D
Type, Density, and Location of Immune Cells within Cholangiocarcinomas Predict Clinical Outcome
Seeßle, J
FATP 4 beeinflusst die Palmitat induzierte Apoptose durch Veränderung des Lipidstoffwechsels
Seidler, S
Der lösliche Urokinase-Plasminogen-Aktivator Rezeptor (suPAR) als neuer diagnostischer und prognostischer Biomarker in der chronischen Lebererkrankung
Seif, A
Niclosamid inhibiert das Wachstum kolorektaler Lebermetastasen durch Reduktion der Wnt-Aktivität
Seigel, B
Hierarchy of inhibitory receptor expression by Hepatitis B Virus (HBV)-specific CD8+ T cells in chronic HBV infection
Seitz, HK
Oxidative stress as antifibrogenic stimulus? Low dose steady state H2O2 induces fibrolytic MMP–3 in vitro and in vivo
Hepatic cytochrome P–4502E1 induction correlates significantly with the degree of steatosis, inflammation, fibrosis and exocyclic etheno DNA-adducts in patients with alcoholic steatohepatitis (ASH) and non-alcoholic fatty liver disease (NAFLD)
Liver stiffness in cardiac insufficiency: Is elevated GGT due to cardiac cirrhosis?
Detection of highly carcinogenic, exocyclic etheno-DNA-adducts in the liver of children with non-alcoholic fatty liver disease
Sellge, G
Modulation of hepatic lipid content by Caspase 8 in non-alcoholic steatohepatitis
Sellinger, M
Protection against Cholestasis and Ischemia in vitro by Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) is Associated with Upregulation of Anti-apoptotic Proteins
Setchell, K
Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) Generates Hepatoprotective conjugated UDCA, Phosphatidylcholine, Medium-chain Fatty acids and Plasmalogen 16: 1
Seufferlein, T
The presence of esophageal varices (EV), but not treatment with beta-blockers, is associated with a poorer survival in patients with cirrhosis and ascites
Seyfarth, HJ
Assoziation genetischer Varianten des CYP2C9 Gens mit einer Hepatotoxizität durch den Endothelinantagonisten Bosentan bei Patienten mit pulmonalarterieller Hypertonie (PAH)
Shen, H
IFN-gamma inhibits hepatic progenitor cell activation in patients with chronic hepatitis B and in mice
Shevchenko, A
Charakterisierung der Smo-KO-induzierten Steatose in der Leber mittels Shotgun-Lipidomanalyse
Sial, GZK
Lactoferrin gene expression upregulation in liver during turpentine oil- or bacterial LPS-induced acute phase reaction
Sibbing, B
Der NKp46-Rezeptor ist an der Regulation der anti-fibrotischen Aktivität von NK Zellen beteiligt
Der CYP27B1–1260 Promoter Polymorphismus rs120877012 ist bei HCV/HIV koinfizierten Patienten signifikant mit einem Ansprechen auf die Therapie der Hepatitis C Erkrankung (SVR) assoziiert
Gestörte Funktion von CD56high CXCR3(+) NK Zellen als möglicher neuer Mechanismus der HCV-assoziierten Leberfibrose
HCV-vermittelte Blockierung der IL–2 Sekretion von CD4(+) T-Zellen hemmt die anti-fibrotische Aktivität von NK-Zellen
Sicinski, P
Non-canonical functions of Cyclin E1 for control of hepatic DNA replication and liver regeneration in mice
Sieber, S
Essential role of Sharpin in TNFα dependent NFκB activation in primary hepatocytes
Siegmund, B
Transfer colitis in Rag1-/-- mice enhances hepatic MMP–9 expression
Siegmund, SV
Analysis of cellular origin and degradation pathways of the endocannabinoid 2-arachidonoyl glycerol during liver fibrogenesis
Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
Singer, MV
Analysis of cellular origin and degradation pathways of the endocannabinoid 2-arachidonoyl glycerol during liver fibrogenesis
Singer, R
A nuclear pore component regulates select p53 target genes
Singer, SR
A nuclear pore component regulates select p53 target genes
Sinn, B
Type, Density, and Location of Immune Cells within Cholangiocarcinomas Predict Clinical Outcome
Sirma, H
Selective induction of apoptosis by HMG-CoA-reductase inhibitors in hepatoma cells is dependent on p53 expression
Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication
Siveke, J
Combination Treatment of Sorafenib and Resminostat, a new HDAC Inhibitor, in Patients with Sorafenib-resistant Hepatocellular Carcinoma (HCC) – Results of the Dose-Escalation Phase
Skibbe, K
The proapoptotic protein Bim is not differentially regulated in CD8+ T cells from resolved or chronic HCV infection
Smirnow, I
Treatment of hepatocellular carcinoma with a novel suicide gene-expressing oncolytic measles vaccine virus
Novel oncolytic Sendai viruses (SeV) for the virotherapeutic treatment of HCC
Soboletzki, M
p53, p63, p73 and the mitochondrial apoptosis signaling pathway in human hepatocellular carcinoma (HCC)
Sobottka, I
Patienten mit Primär Sklerosierender Cholangitis weisen ein gestörtes Gleichgewicht zwischen Foxp3+ regulatorischen T-Zellen und proinflammatorischen Th17 Zellen auf
Söhne, J
Der CYP27B1–1260 Promoter Polymorphismus rs120877012 ist bei HCV/HIV koinfizierten Patienten signifikant mit einem Ansprechen auf die Therapie der Hepatitis C Erkrankung (SVR) assoziiert
Sommerfeld, A
Insulin aggravates free fatty acid-induced hepatocyte cell death by activation of CD95 death receptor pathways in liver
TGR5 (Gpbar–1) is expressed in cholangiocarcinomas and confers apopotosis resistance in isolated cholangiocytes
Src kinase Fyn mediates hyperosmolarity-induced Mrp2- and Bsep-retrieval from the canalicular membrane in a cortactin dependent way
Sowa, JP
Serum sodium based modification of the MELD score does not improve the predictive value in acute liver failure
Characteristics of human non-cirrhotic and cirrhotic liver sections in a novel ex vivo perfusion system
miR–101 im komplexen Zusammenspiel von Steatose und Steatohepatitis bei Nicht-Alkoholischen Fettlebererkrankungen
Spangenberg, HC
Impact of tumor markers in diagnosis of patients with hepatocellular carcinoma (HCC) and their clinicopathologic correlation: an interim analysis
Is Sorafenib an acceptable treatment possibility for patients with advanced hepatocellular carcinoma?
Naturally occurring, tumor-specific CD8+ T cells in patients with hepatocellular carcinoma display a clear immunodominance
speicher, T
Specific therapeutic targeting of liver malignancies by transient depletion of adenosine tri-phosphates
Spengler, U
Ribavirin beeinflusst unterschiedlich die Funktionen von CD4+ TH1-, TH2- und regulatoischen T-Zell-Klonen bei chronischer Hepatitis C
Das CXCL1 rs4074 A Allel führt nach TLR2 Stimulation zu einer verstärkten CXCL1 Expression und ist ein Risikofaktor für Zirrhose bei HCV Genotype 1-infizierten Patienten
Early versus delayed treatment of acute hepatitis C: Final results of the randomized controlled German HEP-NET acute HCV-III study
Der NKp46-Rezeptor ist an der Regulation der anti-fibrotischen Aktivität von NK Zellen beteiligt
Adaptive CD4+ regulatorische T-Zellen regulieren die Fibrogenese durch Produktion von IL–8 bei chronischer Hepatitis C
Der CYP27B1–1260 Promoter Polymorphismus rs120877012 ist bei HCV/HIV koinfizierten Patienten signifikant mit einem Ansprechen auf die Therapie der Hepatitis C Erkrankung (SVR) assoziiert
Gestörte Funktion von CD56high CXCR3(+) NK Zellen als möglicher neuer Mechanismus der HCV-assoziierten Leberfibrose
HCV-vermittelte Blockierung der IL–2 Sekretion von CD4(+) T-Zellen hemmt die anti-fibrotische Aktivität von NK-Zellen
Spomer, L
The proximal TGR5 C-Terminus is required for membrane localization
Sprinzl, MF
Add-on of pegylated interferon alpha–2a (PEG-IFN) triggers antigen-independent TNF-alpha production by CD4+ T cells in patients with pretreated chronic hepatitis B
Hemmung der Makrophagen abhängigen Wachstumsfaktoren durch Sorafenib
Klonierung AFP-spezifischer HLA.A2 allo-restringierter cytotoxischer T-Zellen aus dem naiven T Zell Repertoire
Spruss, A
Fructosereduktion als therapeutischer Ansatz der nicht-alkoholbedingten Fettlebererkrankung (NAFLD) beim Menschen
Einfluss von akutem Bierkonsum auf die Leber: Untersuchungen im Mausmodell
Stabenow, D
Viral infection sensitizes hepatocytes towards TNF-induced apoptosis
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
MHC class I transfer from stellate cells to LSEC allows for sinusoidal immunsurveillance
Staib, F
Mechanistic and therapeutic implications of PDGF-b activation during liver fibrogenesis
Stallmach, A
Pyuria in patients with cirrhosis and its impact on survival
Staratschek-Jox, A
Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation
Stark, K
Phylogenetic Characterization of HEV Isolates Derived from Acute Hepatitis E Cases in Germany 2010/2011
Staufer, K
EpCAM-positive zirkulierende Tumorzellen als möglicher prognostischer Biomarker für ein fortgeschrittenes HCC
Stein, I
RAGE is required for oval cell activation and inflammation-associated mouse liver carcinogenesis
Steinebrunner, N
Analysis of the cytokine response in a mouse model of liver ischemia / reperfusion injury
Steinmann, E
Variants in the human PPIA gene render host cells refractory to hepatitis C virus infection by destabilization of the essential host factor cyclophilin A
Stelzle, M
A Microfluidic 3D Hepatocyte Culture System -HepaChip®- For Drug And Toxicity Investigations
Stenzinger, A
Type, Density, and Location of Immune Cells within Cholangiocarcinomas Predict Clinical Outcome
Stevens, A
Downregulation of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease promotes hepatic inflammation and fibrosis
Stiefel, J
Knochenmarktransplantation in HBV-transgenen Mäusen aggraviert die hepatische Fibrose
Stiefel, P
Chronic hepatitis E in heart transplant recipients
Stieger, B
Intestinal inflammation induces alterations in enterohepatic Fgf15 signalling, changes in hepatic bile acid metabolism and a “toxic bile” composition in DSS-treated mice
Stiehl, A
Concomitant immunological diseases in primary sclerosing cholangitis are a risk factor for reduced survival
Stock, MK
Antagonism of CCL5 chemokine receptors during regression of liver fibrosis is associated with an intrahepatic shift towards pro-inflammatory macrophages
Stock, P
Charakterisierung und hepatozytäre Differenzierung von mesenchymalen Stammzellen aus dem Fettgewebe der immundefizienten Maus
MSCs augment liver regeneration after paracetamol-induced acute liver injury by their anti-apoptotic and pro-proliferative mode of action
Untersuchungen zur dreidimensionalen Kultivierung primärer Rattenhepatozyten auf kollagenierten Silikonscaffolds
Stockmann, M
Valide nicht-invasive Diagnostik einer Leberzirrhose durch Messung der maximalen Leberfunktionskapazität mittels LiMAx-Test
Stoehr, A
The Role of Weight Loss (WL) as On-Tretament Predictive Factor for SVR in the Treatment of Chronic Hepatitis C (CHC) Patients with Peginterferon alfa–2A (PEG) and Ribavirin (RBV)
Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting
Stokes, CS
Vitamin D and depression in chronic liver disease
Strack, I
Sekretionsprofile extrazellulärer miRNA nach myofibroblastischer Transdifferenzierung Hepatischer Sternzellen: Neue Biomarker der Fibrose?
Strand, S
Loss of SIRT6 in hepatocellular carcinomas: associated molecular traits and clinical implications
Strassburg, CP
Regulation der Glukuronidierung bei Cholestase (Gallengangsligatur) und durch FXR-Agonisten im humanisierten transgenen UGT1A-Mausmodell
COMPREHENSIVE IMMUNOPHENOTYPING OF TREGS AND SERUM CYTOKINES MAY HELP TO DISTINGUISH HCV HEPATITIS FROM REJECTION IN LIVER TRANSPLANT PATIENTS
Variants in the human PPIA gene render host cells refractory to hepatitis C virus infection by destabilization of the essential host factor cyclophilin A
Geschlechtsspezifische Regulierung des Detoxifikations-Stoffwechsels: der Estrogen Receptor alpha reguliert die transkriptionelle Regulation von UDP-Glukuronosyltransferasen
Straub, B
Towards unravelling the molecular mechanisms of human hepatocyte steatosis in situ
Streetz, K
Die Transplantation Apoptose-resistenter (Caspase8Dhepa) Hepatozyten führt zur erfolgreichen Repopulation und Reduktion der Entzündungsaktivität im NEMO-/- Mausmodell
c-met vermeidet die Entwicklung Nicht- Alkoholischer- Fettleberhepatitis (NASH) im Mausmodell
Die anti-oxidative Stressantwort schützt via Keap1/NRF2 in Hepatozyten vor chronischer Leberschädigung
Streich, R
Niclosamid inhibiert das Wachstum kolorektaler Lebermetastasen durch Reduktion der Wnt-Aktivität
Stremmel, W
p53, p63, p73 and the mitochondrial apoptosis signaling pathway in human hepatocellular carcinoma (HCC)
Transkriptionelle und Post-Transkriptionelle Regulation von Mcl–1 durch die p53-Familie
Protection against Cholestasis and Ischemia in vitro by Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) is Associated with Upregulation of Anti-apoptotic Proteins
Concomitant immunological diseases in primary sclerosing cholangitis are a risk factor for reduced survival
Analysis of the cytokine response in a mouse model of liver ischemia / reperfusion injury
Das Gallensäure-Phospholipid-Konjugat Ursodeoxycholyl-Lysophosphatidylethanolamid (UDCA-LPE) vermindert die LPS-vermittelte Inflammation in der Leber
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma
Differentielle Regulation von Genen des hepatischen Lipidmetabolismus durch Ursodeoxycholyl Lysophosphatidylethanolamid in verschiedenen diätetischen Modellen der NAFLD
FATP 4 beeinflusst die Palmitat induzierte Apoptose durch Veränderung des Lipidstoffwechsels
Identification of miRNA–34a, miRNA–145 and miRNA–149 as TAp73 and DNp73 targets in hepatocellular carcinoma
Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) Generates Hepatoprotective conjugated UDCA, Phosphatidylcholine, Medium-chain Fatty acids and Plasmalogen 16: 1
ROLE OF TUMOR SUPPRESSORS P53 AND P73 IN THE CELLULAR DEFENCE AGAINST HEPATITIS C VIRUS
Hepatitis B Virus Infection triggers AP–1 dependent CD95Ligand expression in HepG2 cells
Strnad, P
TAA aber nicht CCl4 reduziert Hepcidin-Expression und führt zu einer Eisenüberladung in der Leber
Hepcidin knockout mice as a model of iron-overload associated liver fibrosis development
Krumme Gallengänge prädisponieren zu rezidivierenden Gallengangssteinen
IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
Strüver, N
Transductional Targeting of oncolytic adenoviruses by CARex-pSia adapter molecules improves therapy of pSia-expressing tumors and reduces viral liver load
Stubenrauch, F
Armed oncolytic measles vaccine virus–a novel therapeutic agent for virotherapy of sarcomas of gastrointestinal and non-gastrointestinal origin
Suermann, T
Persistent HCV-infection and liver damage change vitamin-D-metabolism
IL28B allelic variation but not polymorphism of CYP27B1 or genotype of HCV is associated with spontaneous elimination of HCV-infection
IL28B genetic variation and ratio of y-GT/ALT as predictors for virological response in chronic hepatitis C virus genotype 1 infected patients
Sultan, S
Changes of LCN–2 gene expression in different organs in a rat model of tissue damage
Sunami, Y
IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
Suneetha, PV
Chronic hepatitis E in heart transplant recipients
HEV-specific T-cell responses are associated with control of HEV infection
Supplieth, M
Chronische Hepatitis C Infektion: Herausforderung Alter
Sydow, K
Bestimmung des transhepatischen Endotoxin-Gradienten vor und nach Anlage eines transjugulären portosystemischen Shunts (TIPS)
Sykora, J
Expression of TRAIL receptors and cFLIP correlates with grade of malignancy and survival in patients with hepatocellular carcinoma