2015 TLRC Lung Conference

Abels, B

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Aggarwal, N

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Agrawal, R

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Ahuja, S

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Al Alam, D

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Albrecht, T

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Altamura, S

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Anjorin, A

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Aschenbrenner, F

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Backhaus, S

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

Ballester López, C

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice

Baumann, I

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Behler-Janbeck, F

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Bellusci, S

Constitutive Fgf10 deficiency leads to impaired embryonic lung development

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Origin of the smooth muscle cells during murine lung development

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Bertrand, CA

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Biederer, J

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Bodenbenner-Türich, M

Innervation of pulmonary trunk in mice

Bohling, J

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Böhm, ME

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Boutin, S

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Braubach, P

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Braun, A

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Bubnoff, N von

Sequencing of circulating nucleic acids from low serum volumes

Buettner, C

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Bünemann, M

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Burgard, C

Detection of artificial pulmonary lung nodules in Ultralow-Dose CT using an ex vivo lung phantom

Cerwenka, A

Iron levels define two populations of Tumor Associated Macrophages

Chao, CM

Constitutive Fgf10 deficiency leads to impaired embryonic lung development

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Origin of the smooth muscle cells during murine lung development

Chillappagari, S

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Chouvarine, P

Normalization and calibration in the metagenomic analysis of CF lung microbiomes

Christochowitz, S

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Pulmonary allergen clearance is impaired by airway surface dehydration

Chubanov, V

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Conlon, TM

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice

Correia, M

Iron levels define two populations of Tumor Associated Macrophages

Costa da Silva, M

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Iron levels define two populations of Tumor Associated Macrophages

Crestani, B

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dahl, E

Sequencing of circulating nucleic acids from low serum volumes

Dai, L

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Dalpke, A

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Dammann, R

Aberrant DNA methylation of ribosomal RNA genes in lung cancer

De Langhe, S

Origin of the smooth muscle cells during murine lung development

Depner, S

Modeling of TGFb pathway dynamics in lung cancer cells

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Dienemann, H

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

6 years of Certified Lung Cancer Center – The Heidelberg Experience

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Dietz, S

Sequencing of circulating nucleic acids from low serum volumes

Dilai, S

Origin of the smooth muscle cells during murine lung development

Dinkel, J

Detection of artificial pulmonary lung nodules in Ultralow-Dose CT using an ex vivo lung phantom

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Dittrich, AS

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Dittrich, S

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Dopfer, C

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Duerr, J

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Dvornikov, D

Modeling of TGFb pathway dynamics in lung cancer cells

Eberhardt, R

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Ehrhardt, H

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Eichinger, M

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Eickelberg, O

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice

El Agha, E

Origin of the smooth muscle cells during murine lung development

Engel, S

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Engels, L

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Engesser, R

Modeling of TGFb pathway dynamics in lung cancer cells

Esfandiary, A

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Fellenberg, J

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Fink, L

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Firnkorn, D

Data Harmonization and Data Integration Inside the Disease Area Lung Cancer of the German Center for Lung Research

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Flechsig, P

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Frenzel, E

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Frey, A

Novel reagents for the diagnosis of mucin composition in chronic inflammatory airway diseases

Fritzsching, B

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Pulmonary allergen clearance is impaired by airway surface dehydration

Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

Füllekrug, J

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Gaaß, T

Detection of artificial pulmonary lung nodules in Ultralow-Dose CT using an ex vivo lung phantom

Galietta, L

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Ganzinger, M

Data Harmonization and Data Integration Inside the Disease Area Lung Cancer of the German Center for Lung Research

Garapati, V

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Gehrig, S

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Gernert, K

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Gerovasili, V

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Ghofrani, A

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Ghofrani, HA

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Giesel, F

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Gochuico, B

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Gompelmann, D

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Gräber, S

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Graeber, SY

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Granzow, M

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

Grau, V

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

β-NAD inhibits ATP-mediated interleukin-1β release

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Greene, CM

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Grimminger, F

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Gruh, I

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Gudermann, T

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Guenther, A

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Günther, A

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Haag, D

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Haase, A

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Haberkorn, U

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Hagner, M

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Pulmonary allergen clearance is impaired by airway surface dehydration

Haider, G

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Haller, R

Differentiation of human pluripotent stem cells into airway epithelial cells

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Hansen, J

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Happich, M

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Harms, A

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Hass, H

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines

Heath, N

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Hecker, A

β-NAD inhibits ATP-mediated interleukin-1β release

Hecker, M

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Hedtfeld, S

Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Heinzmann, A

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Henke, M

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Henneke, I

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Hentschel, J

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Herpel, E

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Herth, F

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Herth, FJ

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Herth, FJF

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Heussel, CP

6 years of Certified Lung Cancer Center – The Heidelberg Experience

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Simulation study about the accuracy of advanced airway geometry determination on MDCT using a computer-generated phantom

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Heußel, CP

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Hiller, S

β-NAD inhibits ATP-mediated interleukin-1β release

Hirtz, S

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

Hofbauer, T

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Hoffmann, GF

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Hoffmann, H

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Hoymann, HG

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Huber, RM

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Hug, M

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Hühn, M

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Hüttman, G

Optical coherence microscopy for fast intravital imaging of airways in mice and humans with subcellular resolution

Hüttmann, G

Improved endoscopic optical coherence microscopy for imaging of humans airways in patients

Influence of aberrations on the image quality in optical coherence microscopy

Immenschuh, S

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Jaberansari, Z

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Jakob, P

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Janciauskiene, S

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Jia, J

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice

Jimenez, A

Aberrant DNA methylation of ribosomal RNA genes in lung cancer

Jobst, B

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Jonigk, D

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Jurastow, I

β-NAD inhibits ATP-mediated interleukin-1β release

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Kaduthanam, S

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Kahn, N

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Kappes, J

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Kauczor, HU

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Simulation study about the accuracy of advanced airway geometry determination on MDCT using a computer-generated phantom

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Kheirollahi, V

Origin of the smooth muscle cells during murine lung development

Kim, HT

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Klaus, D

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Klepetko, W

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Klingmüller, U

Modeling of TGFb pathway dynamics in lung cancer cells

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Klymenko, O

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Knaup, P

Data Harmonization and Data Integration Inside the Disease Area Lung Cancer of the German Center for Lung Research

Knebel, J

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Knippenberg, S

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Knudsen, L

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Kobinger, S

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Kohlmann, P

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Kohlmüller, D

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Kojonazarov, B

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

König, P

Improved endoscopic optical coherence microscopy for imaging of humans airways in patients

Optical coherence microscopy for fast intravital imaging of airways in mice and humans with subcellular resolution

Influence of aberrations on the image quality in optical coherence microscopy

Konzok, S

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Korfei, M

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Krämer, OH

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Krasteva-Christ, G

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Krause, T

Novel reagents for the diagnosis of mucin composition in chronic inflammatory airway diseases

Kreuter, M

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

Kreutz, C

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Küllmar, M

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

Kulozik, AE

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Kummer, W

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Innervation of pulmonary trunk in mice

β-NAD inhibits ATP-mediated interleukin-1β release

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Kuner, R

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Kuryshev, V

Sequencing of circulating nucleic acids from low serum volumes

Lachmann, N

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Lampe, M

Pulmonary allergen clearance is impaired by airway surface dehydration

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Lee, JH

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Lehmann, WD

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Leitz, D

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Ley, S

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Ley-Zaporozhan, J

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Lill, R

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Lim, HJ

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy

Linder, B

Aberrant DNA methylation of ribosomal RNA genes in lung cancer

MacKenzie, BA

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Maegel, L

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Mahavadi, P

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Maier, E

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Pulmonary allergen clearance is impaired by airway surface dehydration

Mainz, J

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Mall, MA

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Pulmonary allergen clearance is impaired by airway surface dehydration

Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Visualization of channel-activating protease (CAP) activity by peptide-based FRET probes

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Martin, U

Differentiation of human pluripotent stem cells into airway epithelial cells

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Maus, R

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Maus, U

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Maus, UA

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Meister, M

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

Sequencing of circulating nucleic acids from low serum volumes

The Lung Biobank Heidelberg – A 15 Years old Basis for Lung Research

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Menke, S

Differentiation of human pluripotent stem cells into airway epithelial cells

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Merkert, S

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Merkle, R

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Meyerhof, W

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Michael, T

Data Harmonization and Data Integration Inside the Disease Area Lung Cancer of the German Center for Lung Research

Moiseenko, A

Origin of the smooth muscle cells during murine lung development

Moran Losada, P

Normalization and calibration in the metagenomic analysis of CF lung microbiomes

Moritz, T

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Muckenthaler, M

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Muckenthaler, MU

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Iron levels define two populations of Tumor Associated Macrophages

Muley, T

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

Data Harmonization and Data Integration Inside the Disease Area Lung Cancer of the German Center for Lung Research

Sequencing of circulating nucleic acids from low serum volumes

6 years of Certified Lung Cancer Center – The Heidelberg Experience

The Lung Biobank Heidelberg – A 15 Years old Basis for Lung Research

Transcriptome analysis in endobronchial epithelial lining fluid compared to bronchoalveolar lavage in idiopathic pulmonary fibrosis

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Müller-Redetzky, H

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Munder, A

Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Nassenstein, C

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Neves, J

Disruption of the hepcidin/ferroportin regulatory circuitry causes increased pulmonary iron content and restrictive lung disease

Obernolte, H

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Ochs, M

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Olmer, R

Differentiation of human pluripotent stem cells into airway epithelial cells

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Padberg, W

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

β-NAD inhibits ATP-mediated interleukin-1β release

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

Pahn, G

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Pak, O

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Pamidiboina, V

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Panneck, A

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Papadakis, T

Innervation of pulmonary trunk in mice

Pepperkok, R

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Pflaum, M

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Pieper, M

Improved endoscopic optical coherence microscopy for imaging of humans airways in patients

Optical coherence microscopy for fast intravital imaging of airways in mice and humans with subcellular resolution

Influence of aberrations on the image quality in optical coherence microscopy

Pratap Singh Sandhu, S

Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Puderbach, M

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Quispe, G

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Rafiq, A

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Innervation of pulmonary trunk in mice

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Ramaker, K

Novel reagents for the diagnosis of mucin composition in chronic inflammatory airway diseases

Randell, SH

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Raue, A

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Reiser, M

Detection of artificial pulmonary lung nodules in Ultralow-Dose CT using an ex vivo lung phantom

Renz, M

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Richter, A

Aberrant DNA methylation of ribosomal RNA genes in lung cancer

Rickert-Zacharias, V

Visualization of channel-activating protease (CAP) activity by peptide-based FRET probes

Ritter, D

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Rosemarie, K

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Ruppert, C

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Ruth, O

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Saito, S

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Salomon, J

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Salomon, JJ

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Salopiata, F

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schaefer, S

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Schatterny, J

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Schaule, M

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Schelker, M

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schermuly, R

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Schilling, M

Modeling of TGFb pathway dynamics in lung cancer cells

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schindler, S

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Schirmer, U

Sequencing of circulating nucleic acids from low serum volumes

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Schlemmer, HP

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Schlüter, KD

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schmeck, B

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Schmeckebier, S

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Schmidt, S

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Pulmonary allergen clearance is impaired by airway surface dehydration

Schneider, J

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Schneider, MA

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

The Lung Biobank Heidelberg – A 15 Years old Basis for Lung Research

Schreckenberg, R

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schubert, M

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Schultz, C

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Visualization of channel-activating protease (CAP) activity by peptide-based FRET probes

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Schulz, A

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Schulz, R

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schulz-Hildebrandt, H

Improved endoscopic optical coherence microscopy for imaging of humans airways in patients

Optical coherence microscopy for fast intravital imaging of airways in mice and humans with subcellular resolution

Influence of aberrations on the image quality in optical coherence microscopy

Schütz, B

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Sedlaczek, O

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Seeger, W

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Sewald, K

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Seyhan Agircan, A

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Shalashova, I

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Shrestha, A

Origin of the smooth muscle cells during murine lung development

Siebers, R

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Singpiel, A

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Sinnecker, H

Novel reagents for the diagnosis of mucin composition in chronic inflammatory airway diseases

Skwarna, S

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Sommer, N

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Sommerburg, O

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Soultanova, A

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Spahn, S

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Spies, E

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Stahl, M

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany

Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis

Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Stainier, DYR

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Stanke, F

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Stehling, O

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Steiert, B

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Stein, F

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Stelmaszek, D

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Stichnoth, H

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Stiller, W

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Stripecke, R

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Sueltmann, H

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Sültmann, H

Sequencing of circulating nucleic acids from low serum volumes

Sydykov, A

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Szepes, M

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Teschler, S

Aberrant DNA methylation of ribosomal RNA genes in lung cancer

Thomas, M

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

Sequencing of circulating nucleic acids from low serum volumes

6 years of Certified Lung Cancer Center – The Heidelberg Experience

Tian, F

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Tikkanen, R

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

Timmer, J

Modeling of TGFb pathway dynamics in lung cancer cells

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Tort Tarrés, M

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Triphan, S

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Tümmler, B

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease

Normalization and calibration in the metagenomic analysis of CF lung microbiomes

Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Ulrich, M

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling

Ulrich, S

Differentiation of human pluripotent stem cells into airway epithelial cells

van Bodegom, C

Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

Venkatesan, S

Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Vinchi, F

Iron levels define two populations of Tumor Associated Macrophages

Voigt, A

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Wagner, C

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Wang, X

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Warth, A

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma

6 years of Certified Lung Cancer Center – The Heidelberg Experience

The Lung Biobank Heidelberg – A 15 Years old Basis for Lung Research

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Wäsch, M

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Weichert, W

NUT Midline Carcinoma of the Thorax: Case Report and Review of the Literature

Weihe, E

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Weinheimer, O

Simulation study about the accuracy of advanced airway geometry determination on MDCT using a computer-generated phantom

Weinreich, S

Differentiation of human pluripotent stem cells into airway epithelial cells

Weiss, A

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Weissmann, N

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Welte, T

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Diptheria toxin dependent depletion and engraftment kinetics of dendritic cell subsets in the lungs of chimeric zDC+/DTR mice

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Wiebel, M

Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Wiegand, S

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Wiehlmann, L

Normalization and calibration in the metagenomic analysis of CF lung microbiomes

Wielpütz, M

Dynamic contrast-enhanced MRI Perfusion of the Lung – Feasibility and Accuracy in Patients with COPD, lung cancer and pulmonary embolism

Echo-time dependence of observed lung T1 in COPD patients: preliminary results

Wielpütz, MO

Simulation study about the accuracy of advanced airway geometry determination on MDCT using a computer-generated phantom

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Wilker, S

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

β-NAD inhibits ATP-mediated interleukin-1β release

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

Witzenrath, M

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Wrenger, S

Regulation of angiogenesis-related genes in human pulmonary microvascular endothelial cells by alpha1-antitrypsin

Yahya, F

Constitutive Fgf10 deficiency leads to impaired embryonic lung development

Yin, W

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Zabeck, H

Sequential dynamic PET and dynamic MR imaging in N-staging of lung cancer patients

Zakrzewicz, A

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Surfactant inhibits ATP-induced release of interleukin-1β in human monocytes.

β-NAD inhibits ATP-mediated interleukin-1β release

SLPI suppresses ATP-mediated release of IL-1β from human monocytes – evidence for a novel anti-inflammatory mechanism

β-Nicotinamide adenine dinucleotide: a novel bronchodilator inducing increase in intracellular cAMP

Zhou-Suckow, Z

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease

Airway surface dehydration is a novel risk factor for allergic airway inflammation

Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Zimmer, KP

Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Önder Yildirim, A

Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice