2015 TLRC Lung Conference

Abstracts (HTML) List of Authors

Saito, S

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Salomon, J

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Salomon, JJ

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Salopiata, F

The influence of EGF/HGF receptor abundance on therapy resistance in NSCLC cell lines
Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schaefer, S

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension

Schatterny, J

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease
Airway surface dehydration is a novel risk factor for allergic airway inflammation
Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration
Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease

Schaule, M

Impact of epidermal growth factor receptor (EGFR) inhibitors on cisplatin-resistant non-small cell lung cancer (NSCLC) cell lines in parallel to naïve cells at therapeutic doses

Schelker, M

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schermuly, R

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension
Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency
Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

Schilling, M

Modeling of TGFb pathway dynamics in lung cancer cells
Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Schindler, S

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)

Schirmer, U

Sequencing of circulating nucleic acids from low serum volumes
miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Schlemmer, HP

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Schlüter, KD

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schmeck, B

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Schmeckebier, S

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering

Schmidt, S

IL-1 receptor anatagonist anakinra reduces neutrophilic airway inflammation in mice with cystic fibrosis-like lung disease
Pulmonary IL-13 expression is increased by airway surface dehydration in vivo
Pulmonary allergen clearance is impaired by airway surface dehydration

Schneider, J

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Schneider, MA

The Pregnancy Associated Endometrial Protein Glycodelin and its Potential as a Biomarker for Malignant Pleural Mesothelioma
The Lung Biobank Heidelberg – A 15 Years old Basis for Lung Research

Schreckenberg, R

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schubert, M

Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling
Generation of disease-specific iPSCs and development of transgenic reporter cell lines for cystic fibrosis disease modelling and drug screening

Schultz, C

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis
Visualization of channel-activating protease (CAP) activity by peptide-based FRET probes
Small molecule inhibitor of neutrophil elastase reduces emphysema in mice with cystic fibrosis-like lung disease
Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis

Schulz, A

Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Schulz, R

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Schulz-Hildebrandt, H

Improved endoscopic optical coherence microscopy for imaging of humans airways in patients
Optical coherence microscopy for fast intravital imaging of airways in mice and humans with subcellular resolution
Influence of aberrations on the image quality in optical coherence microscopy

Schütz, B

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Sedlaczek, O

Morpho-functional Lung MRI in COPD: Short-term Test-retest Reliability

Seeger, W

MicroRNA-9 is a regulator of PDGFRβ expression in pulmonary arterial hypertension
Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency
Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone
Dysfunctional autophagy in Hermansky-Pudlak syndrome associated lung fibrosis
Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation
Mitochondrial autophagy in the development of amiodarone induced pulmonary fibrosis.

Sewald, K

Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)
Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species

Seyhan Agircan, A

Development of Confocal Reflection Microscopy for the Study of Airway Surface Liquid Dysregulation in Cystic Fibrosis

Shalashova, I

The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

Shrestha, A

Origin of the smooth muscle cells during murine lung development

Siebers, R

Alpha-1 antitrypsin inhibits ATP-induced release of IL-1β in human monocytes via a cholinergic pathway

Singpiel, A

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Sinnecker, H

Novel reagents for the diagnosis of mucin composition in chronic inflammatory airway diseases

Skwarna, S

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone

Sommer, N

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Sommerburg, O

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany
Intestinal Current Measurements Detect Activation of Mutant CFTR in Cystic Fibrosis Patients with the G551D Mutation Treated with Ivacaftor

Soultanova, A

Chemosensory cholinergic signaling network in the thymic medullary epithelium

Spahn, S

Alternative chloride channels in cystic fibrosis (CF): Functional characterization of SLC26A9 in stably-overexpressing FRT epithelial cells

Spies, E

TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms

Stahl, M

Combining IRT/PAP+SN with DNA analysis for the best CF newborn screening strategy for Germany
Comparison of airways' microbiota at different sampling sites in patients with cystic fibrosis
Longitudinal dynamics of cystic fibrosis airways' microbiota during clinical stability and exacerbation

Stainier, DYR

Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse

Stanke, F

Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease
Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model

Stehling, O

MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.

Steiert, B

Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

Stein, F

Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

Stelmaszek, D

Inhibition of profibrotic signaling in fibroblasts from patients with IPF by the pan-histone deacetylase-inhibitor LBH589 or the IPF drug pirfenidone
Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation

Stichnoth, H

Regional differences in Cl- conductance in human nasal epithelial primary cells (hNEpC) of patients with chronic rhinosinusitis

Stiller, W

Quantitative dual-energy computed tomography (DECT) imaging: Evaluation of system performance regarding iodine quantification accuracy

Stripecke, R

Transduction efficacy of bone marrow-derived versus pulmonary macrophages in mice with either lentiviral or adenoviral vectors encoding for GM-CSF

Sueltmann, H

miR-126 is a potential diagnostic marker for malignant pulmonary nodules in endobronchial epithelial lining fluid

Sültmann, H

Sequencing of circulating nucleic acids from low serum volumes

Sydykov, A

Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency

Szepes, M

hiPSC derived endothelial cell types from scalable cultures for biofunctionalization and tissue engineering