Abstracts (HTML) List of Authors

Labenz, C

Das Vorliegen einer minimalen hepatischen Enzephalopathie reduziert die Lebens- und Schlafqualität von Patienten mit Leberzirrhose

Lambert, J

Identification of metabolic prognostic biomarkers in carbon tetrachloride-induced liver fibrosis using MAS-H1-NMR

Lambertz, D

Caspase-8 is a gender-specific modulator of chronic cholestatic liver disease in female Mdr2 knockout mice
Interventional gene targeting of cell cycle regulators identifies Cyclin E1 as a suitable target for attenuating hepatocellular carcinoma progression

Lammert, F

Haemochromatosis (HFE) gene variation and cholangiocarcinoma risk
Systems genetics of liver injury in ABCB4 deficiency: identification of genetic modifiers involved in hepatic cholesterol homeostasis
Increased prevalence of low-frequency- and rare NOD2 variants in patients with cirrhosis treated in tertiary care hepatology centers
Alcohol triggers IL-6 mediated inflammatory response in a new mouse model of acute-on-chronic liver injury
Heterozygous carriage of the alpha1-antitrypsin PiZ variant increases the risk to develop liver fibrosis
Liver Fibrosis and Metabolic Alterations in Adults with Homozygous Alpha1-antitrypsin Deficiency (PiZZ Genotype)
Role of prosteatotic gene variants as modulators of primary sclerosing cholangitis: Analysis of 178 patients with PSC
Alcohol aggravates IL-6 mediated inflammatory response and hepatic steatosis in a new mouse model of acute-on-chronic liver injury
Could inherited predisposition drive fatty liver disease in non-obese Germans? Results from eight tertiary referral centers
Peculiar cases of ibuprofen-induced acute liver failure with distinct outcomes
Effects of gene variants controlling vitamin D metabolism and serum levels on hepatic steatosis

Lang, A

Role of the bile acid receptor TGR5 (GPBAR1) in cholangiocarcinoma (CCA)

Lang, H

Donor but not recipient CRS predicts fibrosis progression after liver transplantation in a large cohort of HCV-positive and negative patients
Alpha-fetoprotein changes prior to therapy predict overall survival of patients with hepatocellular carcinomas
Application of Patient-Derived Liver Cancer Cells in Personalized Treatment Approach: Phenotypic Characterization and Therapeutic Target Identification
Liver vein infiltration in patients with hepatocellular carcinoma in a large German cohort
Deciphering the Role of Transforming Growth Factor Beta (TGF-β1&2) during Tumor Promotion and Suppression in Primary Liver Cancer

Lang, K

CEACAM1 controls immune-mediated liver injury by promoting IL-2-dependent Treg induction

Lang, S

The role of mechanistic target of rapamycin complex 2-component RICTOR in hepatocellular carcinoma progression and sorafenib-resistance

Lange, C

Differential modulation of hepatitis C virus replication and innate immune pathways by synthetic calcitriol analogs
Prospective evaluation of associations between Vitamin D levels and hepatic decompensation and systemic inflammation in patients with liver cirrhosis

Lange, S

Comparison of local tumor control in patients with HCC treated with stereotactic body radiation or TACE: a propensity score analysis

Lange, U

Protective effects of coffee consumption following liver transplantation for hepatocellular carcinoma

Langel, J

Treatment strategies for patients with decompensated liver cirrhosis due to HCV infection – Antiviral treatment or liver transplantation first?

Langhans, B

CD4 regulatory T cells in hepatocellular carcinoma with different etiologies

Lankisch, T

Transjugular diagnostics in fulminant hepatitis including measurements of hepato-central venous biomarker gradients

Laser, H

Einfluss von Diabetes mellitus (Typ 2) auf Inzidenz und Verlauf einer spontan bakteriellen Peritonitis bei Patienten mit Leberirrhose und Aszites

Latz, E

Inability to form NLRP3 inflammasome complex leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation
NLRP6 inflammasome-mediated dysbiosis augments acetaminophen induced acute liver injury

Lautem, A

Donor but not recipient CRS predicts fibrosis progression after liver transplantation in a large cohort of HCV-positive and negative patients

Leber, N

In vivo gene silencing in the liver: Comparison of siRNA-loaded non biodegradable vs. biodegradable nanohydrogel particles for antifibrotic therapy

Lehmann, J

Protective role of VEGF-A165b in liver cirrhosis with portal hypertension

Lempp, F

HBV bypasses the innate immune system and does not protect HCV against the antiviral effect of IFN

Lenschow, C

Evolutionary distance predicts recurrence after liver transplantation in multifocal hepatocellular carcinoma

Li, J

Sicherheit und Praktikabilität der laparoskopischen Leberresektion (LLR) des Hepatozellulären Karzinoms (HCC) bei Leberzirrhose
SOX9 is a crucial transcription factor determining intrahepatic cholangiocarcinoma resistance to chemotherapy

Liao, L

Bacterial translocation and inflammasome activation trigger chronic liver disease in the Mdr2-/- mouse model
Inability to form NLRP3 inflammasome complex leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation
NLRP6 inflammasome-mediated dysbiosis augments acetaminophen induced acute liver injury

Liebisch, G

Irinotecan induced disturbance of bile acid homeostasis promotes hepatocellular injury and inflammation

Liebl, M

Dunbar syndrome in liver transplantation: results of a single center matched-pair analysis and a European survey study

Liedtke, C

Bacterial translocation and inflammasome activation trigger chronic liver disease in the Mdr2-/- mouse model
Caspase-8 is a gender-specific modulator of chronic cholestatic liver disease in female Mdr2 knockout mice
Interventional gene targeting of cell cycle regulators identifies Cyclin E1 as a suitable target for attenuating hepatocellular carcinoma progression

Lindemann, M

Triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis – investigations on 565 patients

Linder, R

Prevalence and “real-life” treatment of autoimmune liver diseases in Germany

Link, R

Clinical management of prescribed co-medication in patients treated with OBV/PTV/r ± DSV ± RBV – Data from the German observational study LIFE-C
Quality of life in HCV patients treated with OBV/PTV/r ± DSV ± RBV under real-life conditions – Data from the German observational study LIFE-C

Liu, X

The CDK4/6 inhibitor Palbociclib and the mTOR inhibitor MLN0128 are effective for the treatment of experimental intrahepatic cholangiocarcinoma

Liwinski, T

The intestinal microbiota of patients with PSC are different from healthy controls and patients with ulcerative colitis across geographical regions

Lohmann, K

Clinical management of prescribed co-medication in patients treated with OBV/PTV/r ± DSV ± RBV – Data from the German observational study LIFE-C
Quality of life in HCV patients treated with OBV/PTV/r ± DSV ± RBV under real-life conditions – Data from the German observational study LIFE-C

Lohr, A

Hepatocellular clear cell foci after combined intraportal pancreatic islet transplantation and knockout of chREBP in diabetic mice

Lohse, A

Autoimmune hepatitis with normal IgG at diagnosis: Subtype without selective elevation of IgG but similar histological features and treatment response
Regorafenib after progression on Sorafenib for advanced HCC
T cell mediated cholangitis alters bile acid metabolism
The intestinal microbiota of patients with PSC are different from healthy controls and patients with ulcerative colitis across geographical regions
Chronic pancreatitis in patients with liver cirrhosis negatively affects graft survival after liver transplantation
Impfverhalten und Immunschutz nach Impfungen bei Patienten mit Leberzirrhose: Ergebnisse eine mono-zentrischen prospektiven Beobachtungsstudie
The suppressive effect of IL-17-expression in antigen specific CD8 T cells in acute experimental cholangitis in mice
Blood-borne HEV transmission: A one year experience with routine HEV screening at a tertiary center
Transfusion-transmitted hepatitis E virus infections: a risk for immunosuppressed patients
Experimentally induced autoimmune hepatitis is initiated by formation of ectopic lymphoid tissue in the liver
Does long-term remission by endoscopic treatment modalities benefit patient and graft survival in biliary strictures after liver transplantation?
Analysis of unconventional T cells identifies intrahepatic type II NKT cells adapting a pro-inflammatory role in autoimmune hepatitis
Metabolic comorbidities in chronic hepatitis B are associated with elevated risks for liver-related events
Interferon α treatment leads to reappearance of the Smc5/6 complex in HBV-infected humanized mice and to its renewed degradation upon viral rebound
Identifizierung neuer MHC I und MHC II restringierter HDV-spezifischer T Zell Epitope
Anti-HEV seroprevalence rate in the Americas
The nucleoprotein High-mobility group box 1 critically regulates the immune response to bacterial infection
Prevalence and “real-life” treatment of autoimmune liver diseases in Germany
Die Biopsieentnahme aus dem rechten und linken Leberlappen erhöht die diagnostische Genauigkeit und kann die Therapieentscheidung beeinflussen
Clinical stabilization of ACLF patients before orthotopic liver transplantation predicts post-transplant survival
Efficacy of HDV mono-infection with genotype 1 and 3 in CRPISPR/Cas generated humanized NTCP mice compared to human liver chimeric mice
Immunosuppression as efficient therapy for Eosinophilic cholangitis: A case series and review of the literature
Mutations in the basal core promoter of HBV lead to intracellular accumulation of viral nucleic acids in vivo
Hepatitis B virus activates expression of the RIG-like receptor pathway in murine intrahepatic cells in humanized mice
Bestimmung der „pitted erythrocytes“ als Marker einer funktionellen Hyposplenie bei Patienten mit Leberzirrhose
Persistierender Aszites nach TIPS-Implantation ist prädiktiv für ein geringeres transplantationsfreies Überleben bei Patienten mit Leberzirrhose
Gender as a negative prognostic factor in Primary biliary cholangitis
Aussagekraft nicht-invasiver Verfahren zur Fibrosequantifizierung bei NAFLD-Patienten mit moderater versus morbider Adopisitas

Longerich, T

Defining the LINC00152-modulated ceRNA network in human hepatocellular carcinoma
Imbalance of scaffold proteins IQGAP1/IQGAP2 in Liver Cancer
Soluble urokinase plasminogen activator receptor (suPAR) represents a novel biomarker for patients undergoing resection of colorectal liver metastases
Impact of modern topical sealants on histopathological changes after hepatectomy: an experimental porcine study
The role of mutations in NOTCH signaling pathway components in liver carcinogenesis
Investigation of exhausted tumor-specific CD8 T cells in orthotopic hepatocellular carcinoma mouse model

Loosen, S

CEA but not CA19 – 9 is an independent prognostic factor in patients undergoing resection of cholangiocarcinoma
Soluble urokinase plasminogen activator receptor (suPAR) represents a novel biomarker for patients undergoing resection of colorectal liver metastases

Lotter, H

A novel mouse model to study effects of cell-autonomous gp130 activation in the liver

Lozanovski, V

Is allocation of liver grafts based on major Extended Donor Criteria plausible? Proposal of an allocation algorithm
Major Extended Donor Criteria predict graft failure and patient mortality after liver transplantation – call for caution

Lu, M

Hepatitis B virus initiates toll-like receptor 2-dependent immune signaling while entering primary human hepatocytes

Lücke, K

A novel mouse model to study effects of cell-autonomous gp130 activation in the liver

Ludwig-Portugall, I

Dynamic role of human ILC3 in the regulation of hepatic fibrogenesis

Luecke, K

The nucleoprotein High-mobility group box 1 critically regulates the immune response to bacterial infection

Luedde, T

CEA but not CA19 – 9 is an independent prognostic factor in patients undergoing resection of cholangiocarcinoma
Soluble urokinase plasminogen activator receptor (suPAR) represents a novel biomarker for patients undergoing resection of colorectal liver metastases

Luft, S

Mutations in the basal core promoter of HBV lead to intracellular accumulation of viral nucleic acids in vivo

Luiken, S

The role of mutations in NOTCH signaling pathway components in liver carcinogenesis

Lurje, G

Hilar en-bloc resection for perihilar cholangiocarcinoma (PHCC); a single-center experience
Dunbar syndrome in liver transplantation: results of a single center matched-pair analysis and a European survey study
Comparative outcome analysis of two-stage hepatectomy with PVE (TSH/PVE) versus ALPPS for patients with colorectal liver metastases (CRLM)
Multimodal treatment modalities are associated with improved long-term outcome in patients with recurrent hepatocellular carcinoma

Lütgehetmann, M

Blood-borne HEV transmission: A one year experience with routine HEV screening at a tertiary center
Transfusion-transmitted hepatitis E virus infections: a risk for immunosuppressed patients
Metabolic comorbidities in chronic hepatitis B are associated with elevated risks for liver-related events
Characterization of the HEV-specific CD8 T-cell response in acute and chronic Hepatitis E virus infection
Interferon α treatment leads to reappearance of the Smc5/6 complex in HBV-infected humanized mice and to its renewed degradation upon viral rebound
Identifizierung neuer MHC I und MHC II restringierter HDV-spezifischer T Zell Epitope
Anti-HEV seroprevalence rate in the Americas
Efficacy of HDV mono-infection with genotype 1 and 3 in CRPISPR/Cas generated humanized NTCP mice compared to human liver chimeric mice
Mutations in the basal core promoter of HBV lead to intracellular accumulation of viral nucleic acids in vivo
Hepatitis B virus activates expression of the RIG-like receptor pathway in murine intrahepatic cells in humanized mice
T cells transiently expressing TCRs against HBV show antiviral activity in HBV/HDV co-infected humanized mice

Lüth, S

Chronic pancreatitis in patients with liver cirrhosis negatively affects graft survival after liver transplantation
Metabolic comorbidities in chronic hepatitis B are associated with elevated risks for liver-related events

Lutz, P

Dynamic role of human ILC3 in the regulation of hepatic fibrogenesis
CD4 regulatory T cells in hepatocellular carcinoma with different etiologies