Abstracts (HTML) List of Authors

Saal, A

Macrophage Migration Inhibitory Factor promotes HCC progression in vivo via the receptor CD74

Saborowski, A

Growth differentiation factor 11 mitigates liver fibrosis via expansion of liver progenitor cells

Saez-Rodriquez, J

Metabolic reprogramming in livers of mice with chronic liver disease

Sagar, S

Persistence of a transcriptional chronic scar on HCV-specific CD8+ T cells after DAA-mediated antigen removal

Sainitin, D

Autoaggression of FOXO1lowCXCR6hiCD8+ T cells causing liver pathology in NASH

Sauer, P

Evaluation of two functional CD24 polymorphisms in primary sclerosing cholangitis
Alteration of the gut microbiota in patients with primary sclerosing cholangitis and concomitant dominant strictures

Savai, R

Fibrocytes contribute to TAA-induced liver fibrosis in mice

Schäfer, J

Loss of Sirtuin6 induces expression of the cancer-related transmembrane protein TMEM45A in HepG2 cells

Schattenberg, J

Vitamin A deficiency is associated with disease severity in patients with liver cirrhosis
Real-world efficacy of elbasvir/grazoprevir in HCV GT1 infected diabetics: results from the German Hepatitis C Registry
Lipid droplet proteins in alcoholic and non-alcoholic steatohepatitis in patients with polymorphisms in PNPLA3
Diagnostic algorithm to detect NASH and fibrosis in NAFLD patients with low NAFLD fibrosis score or liver stiffness

Schattenberg, JM

Hepatic IL-1 signaling in NAFLD is a driver of whole-body insulin resistance and adipose tissue inflammation.
Symptom burden and treatment response in patients with primary biliary cholangitis (PBC)
PNPLA3 and HSD17B13 gene variants exert opposite effects on fatty liver phenotypes: results from the FLAG cohort
Outcome prediction of covert hepatic encephalopathy in liver cirrhosis: comparison of four testing strategies
Extrakorporale Leberunterstützung mit ADVOS in Patienten mit ACLV und HRS – Erste Ergebnisse einer Single Center Studie

Schemmerer, M

In-vitro Activation and anti-viral Function of Innate NK cells in HEV Infection

Schepis, F

Systemic inflammation is associated with hyperdynamic circulation and predicts acute-on-chronic liver failure

Schermuly, R

Fibrocytes contribute to TAA-induced liver fibrosis in mice

Schierwagen, R

Systemic inflammation is associated with hyperdynamic circulation and predicts acute-on-chronic liver failure

Schindeldecker, M

HILPDA is upregulated, predicts prognosis and promotes cancer progression in hepatocellular carcinoma
TGFβ-activated kinase 1 (TAK1) is activated and predicts prognosis in hepatocellular carcinoma

Schindler, P

Predictive parameters and effectiveness of TIPS reduction in treatment of hepatic encephalopathy after TIPS

Schirmacher, P

Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities
Lipid droplet proteins in alcoholic and non-alcoholic steatohepatitis in patients with polymorphisms in PNPLA3
HER2 amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis
Multispectral Imaging to define morpho-molecular classes of human HCC
An umbrella concept for patients with advanced intrahepatic cholangiocarcinoma
Hippo pathway effectors YAP and TAZ are opponents in the regulation of hepatic fibrosis
LINC00152 drives a ceRNA network in human hepatocellular carcinoma
Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control
Quantitative LC-MS-based shot gun proteomics identifies deregulated proteins in gallbladder carcinoma
Dysregulation of Hippo/Yap signaling induces chromosome instability in intrahepatic cholangiocarcinoma
The desmosomal cadherin desmoglein-2 regulates the Hippo pathway effector yes-associated protein (YAP) in liver cancer
The TAZ target gene ITGAV regulates invasion and positively feedbacks on YAP and TAZ in liver cancer cells
Strategies to identify oncogene-dependent long non-coding RNAs (lncRNAs) in liver cancer
Cis-E:N-Cadherin-Heterodimere als Charakteristikum von Tumoren des hepatopankreatobiliären Systems
Mathematical modeling of the YAP/TAZ shuttling as a response to cell density, actin dynamics, and liver damaging drugs
YAP-induced tumor initiation mediates a switch in hepatic macrophage identity via the Ccl2/Ccr2 axis

Schledzewski, K

Der angiokrine HGF-Signalweg steuert die Organ- und Körpergröße sowie die Hepatozytenproliferation

Schlitt, H

Lipid-loaded Hepatocytes fail to Suppress IL-4 Production by Human CD4+ iNKT Cells
In-vitro Activation and anti-viral Function of Innate NK cells in HEV Infection

Schlott, L

Autoimmune hepatitis in mice is enabled by insufficient deletion of autoreactive CD4 T cells and plasticity of Tregs

Schmid, RM

Der angiokrine HGF-Signalweg steuert die Organ- und Körpergröße sowie die Hepatozytenproliferation

Schmid, S

Correlation of Liver Perfusion with Outcome of Patients with Severe Liver Disease – A Prospective Cohort Study

Schmidt, A

PNPLA3 and HSD17B13 gene variants exert opposite effects on fatty liver phenotypes: results from the FLAG cohort

Schmidt, HH

New role of copper transporter ATP7B in lipid metabolism of enterocytes

Schmiel, M

Influence on hepatocellular carcinoma energy metabolism by pharmacological inhibition of the epigenetic modifier LSD1
Overexpression of tumor suppressor miR-198 in hepatoma cells leads to its spontaneous and active export via vesicles

Schmitt, J

Dysregulation of Hippo/Yap signaling induces chromosome instability in intrahepatic cholangiocarcinoma
Cancer stem cells as significant drivers of sorafenib resistance in hepatocellular carcinoma
Mathematical modeling of the YAP/TAZ shuttling as a response to cell density, actin dynamics, and liver damaging drugs

Schmitz, G

Intestinal deletion of fatty acid transport protein 4 in mice increases blood chylomicrons

Schmitz, L

Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming

Schneider, AT

RIPK1 and MLKL in hepatocytes do not mediate Concanavalin A (ConA)-mediated liver toxicity

Schneider, C

Isolated bacterial infection without decompensation has no impact on survival of compensated patients
Die Therapie mit Alpha-1-Antitrypsin (AAT) assoziiert bei AAT-Mangel mit besseren Leber-bezogenen Parametern

Schneider, CV

Europäische Studie: Heterozygoter Alpha-1-Antitrypsinmangel (Pi*MZ) führt zu einem intermediären Leber-Phänotyp
Metabolische Veränderungen bei Erwachsenen mit homozygotem Alpha1-Antitrypsinmangel (Pi*ZZ Genotyp)

Schneider, KM

Metabolic reprogramming in livers of mice with chronic liver disease
Intestinal dysbiosis amplifies acetaminophen induced acute liver injury
The NRF2/KEAP1 pathway in hepatocytes controls fibro- and carcinogenesis in chronic liver disease

Schneider, M

Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control

Schneller, D

RAGE signaling in liver progenitor cells affects fibrosis upon liver injury

Schoedsack, M

The alarmin IL-33 drives a ST2+ Treg-mediated anti-inflammatory immune response during immune-mediated hepatitis

Schöler, U

Real-life efficacy and safety profile of TACE in patients with intermediate HCC in a large German cohort
Retrospective evaluation of RFA and MWA for the treatment of HCC at the University Medical Center Hamburg 2008 – 2016
Improvement in median OS in patients with advanced HCC and strict eligibility criteria receiving Sorafenib

Schöneweis, K

Safety and Efficacy of 10 mg Myrcludex B/IFNa Combination Therapy in Patients with Chronic HBV/HDV Co-Infection

Schönung, M

Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control

Schoonjans, K

The G protein coupled bile acid receptor TGR5 (Gpbar1) modulates endothelin-1 signaling in liver

Schramm, C

Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities
Activation of the arylhydrocarbon receptor sensitizes to acetaminophen-induced acute liver failure
Aberrant expression of activation regulators CBL-B, CTLA-4 and PD-1 in intrahepatic Teff cells in autoimmune hepatitis
Systemic CD4 T cell tolerance induction in the liver depends on interferon-γ and CTLA-4
Single cell RNA sequencing reveals naïve T cells ready for effector function in livers of Primary Sclerosing Cholangitis
Autoimmune hepatitis in mice is enabled by insufficient deletion of autoreactive CD4 T cells and plasticity of Tregs
Soluble CEACAM1 induces activation of STAT5, Foxp3 expression and proliferation of Tregs in DC- T cell cocultures
Nanoparticle-mediated peptide delivery to liver sinusoidal endothelial cells protects from CD8 T cell-driven cholangitis
Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming

Schröder, F

Clomethiazole improves alcoholic fatty liver in patients admitted to the hospital for alcohol detoxification therapy

Schubert, L

PNPLA3 and HSD17B13 gene variants exert opposite effects on fatty liver phenotypes: results from the FLAG cohort

Schubert, S

Apoe- vs. Ldlr-KO: The genetic background determines the function of Oncostatin M in the regulation of lipid homeostasis

Schuller, S

HELLS is an important p53 repression target in liver cancer

Schultheiss, M

Blood reelin levels in the progression of chronic liver disease

Schulze, K

Real-life efficacy and safety profile of TACE in patients with intermediate HCC in a large German cohort
Retrospective evaluation of RFA and MWA for the treatment of HCC at the University Medical Center Hamburg 2008 – 2016
Improvement in median OS in patients with advanced HCC and strict eligibility criteria receiving Sorafenib

Schulze-Osthoff, K

Diagnostic algorithm to detect NASH and fibrosis in NAFLD patients with low NAFLD fibrosis score or liver stiffness

Schumacher, A

Investigation of the glycogen-associated proteome via proximity-biotinylation

Schuppan, D

Hepatic IL-1 signaling in NAFLD is a driver of whole-body insulin resistance and adipose tissue inflammation.
Generation of syngeneic murine hepatoma cells bearing features of human HCC for rapid anti-HCC drug screening
Nanoparticular bisphosphonate to selectively target and repolarize liver macrophages for anti-fibrotic treatment

Schuran, FA

Activation of the arylhydrocarbon receptor sensitizes to acetaminophen-induced acute liver failure
Nanoparticle-mediated peptide delivery to liver sinusoidal endothelial cells protects from CD8 T cell-driven cholangitis

Schwarzkopf, K

Cirrhosis and acute-on-chronic liver failure are linked with aberrant expression of co-stimulatory markers on T-cells

Schweiger, MR

Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming

Schwenzer, J

PNPLA3 and HSD17B13 gene variants exert opposite effects on fatty liver phenotypes: results from the FLAG cohort

Schwinge, D

Activation of the arylhydrocarbon receptor sensitizes to acetaminophen-induced acute liver failure
Systemic CD4 T cell tolerance induction in the liver depends on interferon-γ and CTLA-4
Single cell RNA sequencing reveals naïve T cells ready for effector function in livers of Primary Sclerosing Cholangitis
Autoimmune hepatitis in mice is enabled by insufficient deletion of autoreactive CD4 T cells and plasticity of Tregs
Nanoparticle-mediated peptide delivery to liver sinusoidal endothelial cells protects from CD8 T cell-driven cholangitis

Schwittai, I

Lipid droplet proteins in alcoholic and non-alcoholic steatohepatitis in patients with polymorphisms in PNPLA3

Sebode, M

Aberrant expression of activation regulators CBL-B, CTLA-4 and PD-1 in intrahepatic Teff cells in autoimmune hepatitis
Single cell RNA sequencing reveals naïve T cells ready for effector function in livers of Primary Sclerosing Cholangitis

Seeßle, J

Intestinal deletion of fatty acid transport protein 4 in mice increases blood chylomicrons

Seifert, G

Progression of NAFLD and NASH is mediated by proinflammatory tissue-resident T cells

Seifert, LL

Predictive parameters and effectiveness of TIPS reduction in treatment of hepatic encephalopathy after TIPS

Seitz, H

Clomethiazole improves alcoholic fatty liver in patients admitted to the hospital for alcohol detoxification therapy

Seitz, T

Expression and Function of Fibroblast Growth Factor 9 in hepatocellular carcinoma
Expression and function of Epithelial Splicing Regulatory Protein 1 in hepatocellular carcinoma
Histone deacetylases (HDAC) expressions in HCC and functional effects of HDAC inhibitors in liver cancer cells

Seth, E von

Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities

Seufferlein, T

Wertigkeit der Minilaparoskopie bei der makroskopischen Beurteilung der Lebersteatose

Shao, C

FOXA2 replaces FXR to maintain BSEP expression on bile canaliculi in acute-on-chronic liver failure
Activin-driven fate determination is pivotal for liver progenitor cells to take over hepatocytic function in in ACLF

Sharma, AD

Growth differentiation factor 11 mitigates liver fibrosis via expansion of liver progenitor cells
Clinically applicable liver repopulation: the role of thymidine kinase and ganciclovir (GCV)

Sharma, P

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

Shinde, P

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

Sieker, J

HELLS is an important p53 repression target in liver cancer

Simon, KG

Real-world efficacy of EBR/GZR in HCV GT1 patients with multiple comorbidities and medications: results from the DHC-R
Real-world efficacy of elbasvir/grazoprevir in HCV GT1 infected diabetics: results from the German Hepatitis C Registry

Singer, S

HELLS is an important p53 repression target in liver cancer

Singh, I

Antioxidant-based therapy in non-alcoholic steatohepatitis (NASH) and NASH-induced hepatocellular carcinoma development
A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

Sinha, A

Adverse effects of PD-1 targeted immunotherapy in NAFLD-triggered HCC

Skawran, B

LINC00152 drives a ceRNA network in human hepatocellular carcinoma

Smits, M

HCV-specific CD4 T cells show strong Tfh functionality after DAA-mediated viral clearance
Cytokine patterns of newly identified HEV-specific CD4 T cell epitope

Smyk, W

Common genetic variant c.711A>T in the hepatobiliary phospholipid translocator ABCB4 as risk factor for liver fibrosis

Soborowski, A

RAGE signaling in liver progenitor cells affects fibrosis upon liver injury

Sommer, J

Analysis of the expression and function of KIAA1199 in hepatocellular carcinoma
Expression and Function of Four-and-a-Half LIM-domain protein 2 (FHL2) in Hepatic Fibrosis
Expression and Function of Four-and-a-Half LIM-domain protein 2 (FHL2) in Hepatocellular Carcinoma

Song, G

Growth differentiation factor 11 mitigates liver fibrosis via expansion of liver progenitor cells

Sonntag, R

Genetic or pharmacological inhibition of cyclin-dependent kinase 2 in Hepatic Stellate Cells acts anti-fibrotic
Genetic fine analysis of the pro-fibrotic and pro-carcinogenic functions of Cyclin E1 in the liver

Spormann, L

The interaction of Hedgehog and mTor signaling in healthy hepatocytes

Springfeld, C

HER2 amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis
An umbrella concept for patients with advanced intrahepatic cholangiocarcinoma

Sprinkart, AM

Low muscle mass and large portosystemic shunt in “one-stop shop” CT exponentially increases risk for HE and mortality

Sprinzl, M

Epidemiologie und Auswirkungen bakterieller Infektionen bei stationären Patienten mit Leberzirrhose

Stadler, M

Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control

Staffer, S

Deletion of fatty acid transport protein 4 in HepG2 cells increases lipolysis lipids and lipoprotein secretion

Stäheli, P

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

Stallmach, A

Inflammatory peritoneal MAIT cells accumulate during the early phase of spontaneous bacterial peritonitis
CD206 expression characterizes an inflammatory, resident human peritoneal macrophage subset in decompensated cirrhosis
Antibiotische Therapie von Leberabszessen: Enterokokken sind eine häufige Ursache für ein Therapieversagen

Steffen, HM

Phenotyping non-alcoholic fatty liver disease by the gut microbiota – ready for prime time?

Stein, K

PNPLA3 and HSD17B13 gene variants exert opposite effects on fatty liver phenotypes: results from the FLAG cohort

Stein, S

Nanoparticle-mediated peptide delivery to liver sinusoidal endothelial cells protects from CD8 T cell-driven cholangitis

Stelzer, D

SEAL program – Early detection of liver fibrosis and cirrhosis by screening of the general population

Stengel, S

Inflammatory peritoneal MAIT cells accumulate during the early phase of spontaneous bacterial peritonitis
CD206 expression characterizes an inflammatory, resident human peritoneal macrophage subset in decompensated cirrhosis

Stenzel, P

Cis-E:N-Cadherin-Heterodimere als Charakteristikum von Tumoren des hepatopankreatobiliären Systems

Stenzinger, A

Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals novel therapeutic opportunities
An umbrella concept for patients with advanced intrahepatic cholangiocarcinoma

Stepanova, T

Safety and Efficacy of 10 mg Myrcludex B/IFNa Combination Therapy in Patients with Chronic HBV/HDV Co-Infection

Stepanow, S

Whole exome sequencing analysis revealed an inherited AKR1D1 defect in twins with infantile intrahepatic cholestasis

Steube, A

CD206 expression characterizes an inflammatory, resident human peritoneal macrophage subset in decompensated cirrhosis

Steudter, A

Activation of the arylhydrocarbon receptor sensitizes to acetaminophen-induced acute liver failure

Sticht, C

The TAZ target gene ITGAV regulates invasion and positively feedbacks on YAP and TAZ in liver cancer cells
Strategies to identify oncogene-dependent long non-coding RNAs (lncRNAs) in liver cancer
YAP-induced tumor initiation mediates a switch in hepatic macrophage identity via the Ccl2/Ccr2 axis

Stindt, J

The G protein coupled bile acid receptor TGR5 (Gpbar1) modulates endothelin-1 signaling in liver

Stindt, S

Neuregulin-1 down-regulates expression of ErbB3 expression in hepatoma cell lines at the level of transcription
The Hepatitis C Virus influences CXC chemokine expression of infected host cells in response to IL-1β

Stock, P

Improved Hepatogenic Differentiation of Human Adipose Tissue-derived MSCs Using a Silicone-based Cell Culture System

Stöckmann, N

Diagnostic algorithm to detect NASH and fibrosis in NAFLD patients with low NAFLD fibrosis score or liver stiffness

Stoehr, A

Real-world efficacy of EBR/GZR in HCV GT1 patients with multiple comorbidities and medications: results from the DHC-R
Real-world efficacy of elbasvir/grazoprevir in HCV GT1 infected diabetics: results from the German Hepatitis C Registry

Stottmeier, B

Oxygenation and miR138-5 p act as rheostats in APOBEC3B-mediated Hepatitis B Virus control

Strand, D

Deletion of Sirtuin 6 affects tumor-directed innate immune responses in a syngeneic mouse model of hepatocellular carcinoma
Loss of Sirtuin6 induces expression of the cancer-related transmembrane protein TMEM45A in HepG2 cells

Strand, S

Deletion of Sirtuin 6 affects tumor-directed innate immune responses in a syngeneic mouse model of hepatocellular carcinoma
Loss of Sirtuin6 induces expression of the cancer-related transmembrane protein TMEM45A in HepG2 cells

Strassburg, C

Low muscle mass and large portosystemic shunt in “one-stop shop” CT exponentially increases risk for HE and mortality
Dental health needs assessment and treatment in patients awaiting liver transplant

Straub, B

HILPDA is upregulated, predicts prognosis and promotes cancer progression in hepatocellular carcinoma
Cis-E:N-Cadherin-Heterodimere als Charakteristikum von Tumoren des hepatopankreatobiliären Systems
TGFβ-activated kinase 1 (TAK1) is activated and predicts prognosis in hepatocellular carcinoma

Straub, BK

Hepatic IL-1 signaling in NAFLD is a driver of whole-body insulin resistance and adipose tissue inflammation.
Lipid droplet proteins in alcoholic and non-alcoholic steatohepatitis in patients with polymorphisms in PNPLA3

Stremmel, W

Intestinal deletion of fatty acid transport protein 4 in mice increases blood chylomicrons

Strnad, P

Europäische Studie: Heterozygoter Alpha-1-Antitrypsinmangel (Pi*MZ) führt zu einem intermediären Leber-Phänotyp
Metabolische Veränderungen bei Erwachsenen mit homozygotem Alpha1-Antitrypsinmangel (Pi*ZZ Genotyp)
Die Therapie mit Alpha-1-Antitrypsin (AAT) assoziiert bei AAT-Mangel mit besseren Leber-bezogenen Parametern

Strowig, T

Intestinal dysbiosis amplifies acetaminophen induced acute liver injury

Strunz, B

Soluble inflammatory molecules do not completely normalize despite early treatment of acute symptomatic hepatitis C

Sturm, L

Blood reelin levels in the progression of chronic liver disease

Sunami, Y

Hepatic activation of FOXO3 regulates mTORC2-Akt and enhances oxidative damage-associated hepatocellular carcinogenesis

Sydor, S

Hepatic steatosis in Crohn's disease: associations with anti-TNFα treatment, dysbiosis, and FGF-19.

Sydykov, A

Fibrocytes contribute to TAA-induced liver fibrosis in mice