Abstracts (HTML) List of Authors

Haas, Victor

Virulent Enterococcus faecalis from individuals with Primary Sclerosing Cholangitis crosses the intestinal barrier and induces liver inflammation in Mdr2 -/- mice

Habib, Nagy

Characterization of T cell subsets and dynamic remodeling following immune checkpoint inhibition in hepatocellular carcinoma

Haedge, Frederic

Comparative analysis of surrogate markers of intestinal permeability, bacterial translocation, and gut vascular barrier damage in cirrhosis

Haferkamp, Sebastian

Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis

Hagen, Maximilian

Metabolic reprogramming of HBsAg-positive hepatocytes after stimulation with Schistosoma mansoni egg antigens

Haghpanah, Alireza

MR guided catheter-based radiotherapy/brachytherapy of liver tumours – first experience and feasibility

Hahn, Magdalena

Liver Transplantation after Immune Checkpoint Inhibition in HCC Patients: Insights from an International Multicenter Registry

Hahn, Nele

Intestinal Barrier Disruption in Liver Cirrhosis: Bacteria-mediated Cell Junction Degradation and p53-Mediated Paraptosis in Spontaneous Bacterial Peritonitis

Hahn, Sigrid

Feasibility and Mortality Prediction of Bedside Rectus Femoris Muscle Ultrasound for Sarcopenia Diagnosis in Liver Cirrhosis

Hähnel, Viola

ECP as a potential treatment for liver rejection after transplantation – influence of cell death on T cell activation

Haller, Dirk

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Halliday, Anna

Clinically significant itch on the PBC-40 corresponds to moderate-severe itch on the worst itch numerical rating scale (NRS) in patients with pruritus and primary biliary cholangitis (PBC)

Hammad, Seddik

Multi-Omics Gene Signatures Predict Disease Trajectory in a Cholestasis-Based ACLF Mouse Model
Stabilin1 mediates ingestion of oxidized erythrocytes by LSECs (efferocytosis)
TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs
Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency
Extracellular matrix protein 1 (ECM1) balances liver regeneration by interfering with HGF/c-Met-ERK-MYC and TGF-β-SMAD signaling pathways
Cell type specific decoding of TGF-β2 production, signaling and outcome in the dynamics of cholestatic liver disease
TGF-β-SMAD axis plays an essential role in the regulation of LPC proliferation and performing hepatocyte function in acute liver failure

Hammad, Stella Seddik

Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency

Hammerich, Linda

Association of the Genetic Variant VEGFA rs3025039 with Incidence and Prognosis of Cholangiocarcinoma

Hampe, Jochen

Dynamics of disease progression and regeneration in a multiscale liver model
Predicting Controlled Attenuation Parameter and Elastographic Modulus from Handheld Ultrasound Device Data using Machine Learning

Han, Feng

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Hanesch, Lorenz

Chimeric VSV-NDV mediates a multimechanistic therapeutic response supported by immune activation in orthotopic hepatocellular carcinoma
Immunoregulation and MDSC-Mediated T Cell Paralysis in Hepatocellular Carcinoma Following rVSV-NDV Therapy

Haque, Madhuri

Machine learning identifies microbiome associations with MASLD biomarkers

Harberts, Aenne

Low rates of positive evaluation and early liver transplantation (LT) for acute-on-chronic liver failure (ACLF) in a European tertiary referral center
Expression signatures of IL-18 and IL-18BP characterize stages of cirrhotic decompensation

Harst, Ida

Cell type specific decoding of TGF-β2 production, signaling and outcome in the dynamics of cholestatic liver disease

Hartel, Anna-Lena

NF-κB reactivation in TAK1LPC-KO mice induces lethal cholemic nephropathy

Hartl, Johannes

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Hartl, Lukas

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage

Hartmann, Daniel

Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC
Icer Knockout Influences the Development of Primary Liver Cancer by Promoting Macrophage Infiltration
Brg1 suppress DEN-induced hepatocellular carcinogenesis in mice
ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Hassan, Mohsin

Unveiling Cellular Heterogeneity and Liver Pathophysiology in Liver Transplant Recipients through Multiplex Image Analysis

Hassan, Reham

TLR4 and CD14 as potential therapeutic targets for LPS-induced acute-on-chronic liver failure
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Hassani, Majda El

Comparative analysis of surrogate markers of intestinal permeability, bacterial translocation, and gut vascular barrier damage in cirrhosis

Hauner, Hans

Association of the PNPLA3 p.I148M common variant with increased resting energy expenditure in the context of cold adaptation in humans

Heeren, Jörg

Intrahepatic T cell responses modulate thermogenic adaptation in adipose tissues

Heger, Lukas

Right ventricular contractility predicts clearance of ascites after transjugular intrahepatic portosystemic shunt (TIPS)

Heide, Danijela

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Heidrich, Benjamin

Reduzierte Inzidenz von Peritonitis und verringerte Explantationsrate durch Beimengung von Silberpartikeln bei getunnelten Peritonealkathetern bei Patient*innen mit refraktärem Aszites

Heij, Lara R

Cell type specific decoding of TGF-β2 production, signaling and outcome in the dynamics of cholestatic liver disease

Heikenwälder, Mathias

A 5:2 intermittent fasting regimen ameliorates MASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
Hepatocarcinogenesis and metabolic control of immunosuppression by ATF6a-driven ER-stress
Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx
Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Heine, Johannes

Patient safety, trans-sectoral quality of care, cost efficiency and interprofessional competence: An analysis of the interprofessional training wards A-STAR in comparison to conventional wards with a hepatological focus at Regensburg University Hospital

Heinrich, Bernd

Granzyme profiles in CXCR6+PD-1+CD8+T cells differentiate acute and chronic hepatitis flares and may reflect intrahepatic immune imprints

Heinrich, Sophia

Liver Transplantation after Immune Checkpoint Inhibition in HCC Patients: Insights from an International Multicenter Registry

Held, Anna

High copper levels induce inflammation and oxidative stress in a cell culture model of Wilson's disease

Hellendahl, Elisa

High proportion of complicated treatment courses in patients with chronic hepatitis E infection: Men and older patients may have higher risk for viral relapse, real life data from single centre

Hellerbrand, Claus

Hepatic stellate cells show protumorigenic effects on melanoma cells
Expression and function of G protein-coupled receptor 37 in hepatocellular carcinoma
The role of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) in hepatocellular carcinoma
Uptake of fatty acids and lipid accumulation promote prometastatic characteristics of colorectal cancer cells

Hendawi, Rama

TLR4 and CD14 as potential therapeutic targets for LPS-induced acute-on-chronic liver failure
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Hengstler, Jan

Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency
TLR4 and CD14 as potential therapeutic targets for LPS-induced acute-on-chronic liver failure
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy
Cross-cellular interactions between hepatocytes and cholangiocytes: The role of NF-κB pathways in hepatocarcinogenesis
NF-κB reactivation in TAK1LPC-KO mice induces lethal cholemic nephropathy

Heni, Carolin

HBsAg-specific CD4 T cell response in HBV vaccinated individuals

Henkel-Oberländer, Janin

Dynamic changes in macrophage populations in MASLD and its influence on prostaglandin E2-mediated signaling

Heo, Jeong

Efficacy and Safety of Seladelpar in Patients With Primary Biliary Cholangitis and Compensated Liver Cirrhosis in the Open-Label, Long-Term ASSURE Safety Study: Interim Results

Herebian, Diran

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Herkel, Johannes

T cell hyporesponsiveness distinguishes Autoimmune Hepatitis from Drug-Induced Liver Injury
CRISPR/Cas9-mediated Cxcr3 gene knock-out in unstimulated murine primary CD4+T cells
Tolerance induction by liver sinusoidal endothelial cells is preserved in liver fibrosis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Hermanns, Heike

Long-term outcomes of Metabolic dysfunction associated steatotic liver disease (MASLD) patients in a prospective, German real-world cohort

Hermanns, Heike M.

Robust acute-phase response highlights necessity of time-matched sham-operated controls in early liver ischemia/reperfusion injury studies

Hernando, Diego

Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank

Herzberger, Lisa

In vitro characterization of the drug metabolizing capacity of hepatocytes from MASH livers and development of a PK model for MASH patients

Herzen, Julia

Using X-Ray Microscopy to Visualize 3D Architecture of Native Spheroid and Organoid Samples

Herzog, Moritz

Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank
Predicting Controlled Attenuation Parameter and Elastographic Modulus from Handheld Ultrasound Device Data using Machine Learning

Hesser, Jürgen

Comparative evaluation of standard machine learning models for liver fibrosis detection

Hetzer, Jenny

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Heumann, Philipp

Impact of Additive Chemotherapy on Survival in Stage IV Colon Cancer Patients Following Liver Metastasectomy: A Retrospective Analysis with a Focus on Chemotherapy Regime Efficacy
How physical activity affects quality of life in patients with UICC IV hepatobiliary and gastrointestinal cancer undergoing systemic therapy
Digital single-operator cholangioscopy characterizes distinct phenotypes of primary sclerosing cholangitis

Heusner, Carrie

Efficacy and Safety of Seladelpar in Patients With Primary Biliary Cholangitis and Compensated Liver Cirrhosis in the Open-Label, Long-Term ASSURE Safety Study: Interim Results

Heuveline, Vincent

Comparative evaluation of standard machine learning models for liver fibrosis detection

Heymann, Felix

Unveiling Cellular Heterogeneity and Liver Pathophysiology in Liver Transplant Recipients through Multiplex Image Analysis

Heyne, Renate

Overweight, but not alcohol is associated with increased risk for advanced liver disease in patients with chronic hepatitis C infection- results from the German Hepatitis C-Registry (DHC-R)

Hildegard Wirtz, Theresa

HOPE treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation

Hinrichs, Jan

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage

Hirner-Eppeneder, Heidrun

Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer

Hirschberger, Anna

Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC

Hirschfield, Gideon M.

Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial
Baseline Characteristics and Risk Profiles of 1111 Patients With Primary Biliary Cholangitis (PBC) in Need of Second-Line Therapy

Hischebeth, Gunnar T.R.

Microbial detection in peritonitis may be faster by automated molecular methods, but less sensitive, which also depends on cause of peritonitis

Hobeika, Bernard

Adiposity and myosteatosis are prognostic biomarkers in advanced HCC patients receiving immunotherapy
Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte

Hobloss, Zaynab

TLR4 and CD14 as potential therapeutic targets for LPS-induced acute-on-chronic liver failure
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Höchst, Bastian

Chimeric VSV-NDV mediates a multimechanistic therapeutic response supported by immune activation in orthotopic hepatocellular carcinoma
Immunoregulation and MDSC-Mediated T Cell Paralysis in Hepatocellular Carcinoma Following rVSV-NDV Therapy

Hoehme, Stefan

Dynamics of disease progression and regeneration in a multiscale liver model
Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Hofmaier, Jan

Single Shot Liver: MR-guided stereotactic body radiotherapy (SBRT) for hepatic malignancies and metastasis

Hofmann, Ilse

Repurposing passenger amplifications for specific therapeutic targeting of liver and other solid cancers

Hofmann, Maike

HBsAg-specific CD4 T cell response in HBV vaccinated individuals
Skewed HBV-specific CD8+T cell repertoire in chronic versus acute-resolving HBV infection
No evidence for viral escape mutations in immunodominant CD4 HCV-specific epitopes
Focal Adhesion Kinase (FAK)-Dependent Immune Escape in Hepatocellular Carcinoma

Hofmann, Ute

TLR4 and CD14 as potential therapeutic targets for LPS-induced acute-on-chronic liver failure
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Hofstetter, Pia

Digital single-operator cholangioscopy characterizes distinct phenotypes of primary sclerosing cholangitis

Hohenester, Simon

Clinically significant itch on the PBC-40 corresponds to moderate-severe itch on the worst itch numerical rating scale (NRS) in patients with pruritus and primary biliary cholangitis (PBC)
Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial

Hohenschwert, Johan

HOPE treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation

Hollfoth, Vanessa

Proteomic profiling of FFPE liver specimens of biliary atresia patients

Holzmann, Bernhard

Icer Knockout Influences the Development of Primary Liver Cancer by Promoting Macrophage Infiltration
ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Holzner, Philipp

Focal Adhesion Kinase (FAK)-Dependent Immune Escape in Hepatocellular Carcinoma
Spatial analysis of the tumor immune microenvironment in Biliary Tract Cancer

Hong, Xupeng

A DNA launch method for HBV infection in human hepatocyte chimeric mice enables isogenic studies of basal-core promoter and precore mutants

Hoppmann, Hauke

Establishment and Validation of the new LIVERAID-ICU Score for Prognostic Assessment in Patients with Liver Cirrhosis and Infections in the Intensive Care Unit

Hörauf, Achim

Microbial detection in peritonitis may be faster by automated molecular methods, but less sensitive, which also depends on cause of peritonitis

Horn, Paul

Association of the Genetic Variant VEGFA rs3025039 with Incidence and Prognosis of Cholangiocarcinoma

Hornung, Matthias

Soluble CD46 as a diagnostic biomarker for steatotic liver disease

Horst, David

Association of the Genetic Variant VEGFA rs3025039 with Incidence and Prognosis of Cholangiocarcinoma

Horst, Ludwig

Sarcoidosis of the Liver – An underdiagnosed entity
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Horst, Ludwig Jesse

Circulating matricellular fibrosis markers TSP2, IGFBP7, TSP4 and the M2-macrophage marker CD163 in predicting disease stage and progression in primary sclerosing cholangitis

Hoxha, Elion

Analysis of HEV infection rates in immunocompetent MPGN patients compared to controls

Huang, Chenjun

Genomic Alterations and Tumor Immune Microenvironment as Predictors of Immunotherapy Outcomes in Advanced Biliary Tract Cancer
Extracellular matrix protein 1 (ECM1) balances liver regeneration by interfering with HGF/c-Met-ERK-MYC and TGF-β-SMAD signaling pathways

Huang, Honglian

Genomic Alterations and Tumor Immune Microenvironment as Predictors of Immunotherapy Outcomes in Advanced Biliary Tract Cancer

Huang, Patrick

Activating Mucosal-Associated Invariant T (MAIT) cells for next generation immunotherapy of liver cancer

Hübener, Peter

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage
Low rates of positive evaluation and early liver transplantation (LT) for acute-on-chronic liver failure (ACLF) in a European tertiary referral center
Expression signatures of IL-18 and IL-18BP characterize stages of cirrhotic decompensation

Huber, Julia

Intestinal Barrier Disruption in Liver Cirrhosis: Bacteria-mediated Cell Junction Degradation and p53-Mediated Paraptosis in Spontaneous Bacterial Peritonitis

Huber, Michael

Rare but there: Novel approaches to discover hepatic mast cell functions in liver fibrosis

Huber, Patrick

Low risk of variceal bleeding in chronic non-cirrhotic portal vein thrombosis

Huber, Samuel

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab
Low rates of positive evaluation and early liver transplantation (LT) for acute-on-chronic liver failure (ACLF) in a European tertiary referral center
Expression signatures of IL-18 and IL-18BP characterize stages of cirrhotic decompensation

Huber, Tobias

Analysis of HEV infection rates in immunocompetent MPGN patients compared to controls

Hübner, Norbert

Single-nuclei RNA-sequencing of human liver samples reveals heterogeneity and compositional changes of biliary epithelial cell subpopulations during the progression of primary sclerosing cholangitis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Hundertmark, Jana

Inhibition of the chemokine CXCL12 promotes liver cancer progression by modulating the inflammatory and angiogenic tumor microenvironment

Hünergard, Juliana

Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx

Hupa-Breier, Katharina

Overweight, but not alcohol is associated with increased risk for advanced liver disease in patients with chronic hepatitis C infection- results from the German Hepatitis C-Registry (DHC-R)

Hüser, Norbert

The pivotal role of infected hepatocytes in determining the outcome of antiviral CD8 T cell immunity in the liver
Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC
Icer Knockout Influences the Development of Primary Liver Cancer by Promoting Macrophage Infiltration
Brg1 suppress DEN-induced hepatocellular carcinogenesis in mice
ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Hutchinson, James

ECP as a potential treatment for liver rejection after transplantation – influence of cell death on T cell activation
Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis
Soluble CD46 as a diagnostic biomarker for steatotic liver disease
Angiopoietin-1 Receptor (CD202b) Identifies IL-4-secreting Human Invariant Natural Killer Cells

Huth, Thorben

ROBO receptors function as tumor suppressors in cholangiocarcinoma