Abstracts (HTML) List of Authors

Kabelitz, Martin Andreas

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage
Value of plasma ammonia levels to predict hepatic encephalopathy after transjugular intrahepatic portosystemic shunt insertion

Kadioglu, Amine

Interaktion zwischen metabolischen Faktoren und Genetik am Beispiel Alpha-1-Antitrypsin-Mangel

Kager, Juliane

The anti-tumour effector function of mucosal-associated invariant T cells against hepatocellular carcinoma is impaired by fatty acids and aberrant lipid metabolism
Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC

Kah, Janine

Analysis of the CXCL9-11 mediating recruitment of CXCR3+CD4 T cells to HDV-infected livers

Kahlhöfer, Julia

Unterschiedliche Cluster des intestinalen Mikrobioms bei fortgeschrittener Leberzirrhose korrelieren mit Antibiotikabehandlung, Störungen der Darmbarriere und systemischer Inflammation

Kaiser, Nico

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Kallenbach, Michael

Artificial Intelligence for differentiation of focal liver lesions using contrast-enhanced ultrasound (CEUS)
Two cases of hepatic lues demonstrating the highly variable presentation of syphilis

Kandler, Jennis

CLEAN-DUCT / TRITICC-3 (IKF070) – A Phase IIa, Prospective, Single-Arm, Open-Label, Non-Randomized, Multi-Center Pilot Study of Durvalumab+Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

Kandulski, Arne

Impact of Additive Chemotherapy on Survival in Stage IV Colon Cancer Patients Following Liver Metastasectomy: A Retrospective Analysis with a Focus on Chemotherapy Regime Efficacy
How physical activity affects quality of life in patients with UICC IV hepatobiliary and gastrointestinal cancer undergoing systemic therapy
Digital single-operator cholangioscopy characterizes distinct phenotypes of primary sclerosing cholangitis
Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte
Intestinal Barrier Disruption in Liver Cirrhosis: Bacteria-mediated Cell Junction Degradation and p53-Mediated Paraptosis in Spontaneous Bacterial Peritonitis
A Biliary Organoid Approach to Study the Transition from Primary Sclerosing Cholangitis to Cholangiocarcinoma

Kang, Grace

Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial

Kang, Yoon Koo

Five-year overall survival (OS) and OS by tumour response measures from the Phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)

Kapinsky, Michael

Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis

Kappel, Julia

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage

Kappenberg, Franziska

Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Karbannek, Henrik

Influence of low-dose acetylsalicylic acid on renal function in patients with liver cirrhosis and ascites

Karimi, Mohammad

A 5:2 intermittent fasting regimen ameliorates MASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1

Karin, Monika

PD-L1 expressing circulating tumor cells to predict survival in patients with advanced hepatocellular carcinoma treated with immunotherapy: a prospective, multicenter study
Adiposity and myosteatosis are prognostic biomarkers in advanced HCC patients receiving immunotherapy

Karl, Anna Sophie

Novel predictors of major adverse liver outcomes employing the UK Biobank

Karlsen, Tom

Distinct gene pathways and cell types define peribiliary disease states in PSC

Kather, Jakob Nikolas

Artificial Intelligence for differentiation of focal liver lesions using contrast-enhanced ultrasound (CEUS)
Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank

Kaufman, Randal J.

Hepatocarcinogenesis and metabolic control of immunosuppression by ATF6a-driven ER-stress

Kaufmann, Benedikt

Brg1 suppress DEN-induced hepatocellular carcinogenesis in mice

Kaur, Senamjit

Safety and efficacy of Upadacitinib in patients with primary sclerosing cholangitis: a multicentre, retrospective study

Kaur, Surmeet

S. mansoni infection of HBsAg-transgenic mice elicits hepatocellular damage, hepatic decompensation and carcinogenesis

Kautz, Achim

Symptom Self-Reporting in PBC: Consolidated results of a Mobile App Approach

Keitel, Verena

Genetic Variant Analysis in Low Phospholipid-Associated Cholelithiasis Patients through Whole Exome Sequencing
Clinical effectiveness of two courses of gemcitabine/cisplatin/durvalumab re-administration after failure of durvalumab maintenance therapy in a patient with intrahepatic cholangiocarcinoma
Cell type specific decoding of TGF-β2 production, signaling and outcome in the dynamics of cholestatic liver disease

Keller, Marie

Unraveling MASH: Kupffer Cell-Driven Inflammation and Fibrosis within Hepatic Spheroids as a 3D Disease Model

Kelley, Robin Kate

Five-year overall survival (OS) and OS by tumour response measures from the Phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)

Kempski, Jan

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

Kent, Alexandra

Safety and efficacy of Upadacitinib in patients with primary sclerosing cholangitis: a multicentre, retrospective study

Kestel, Johanna

Long-term outcomes of Metabolic dysfunction associated steatotic liver disease (MASLD) patients in a prospective, German real-world cohort

Ketteler, Lutz

Assessment of Liver Fibrosis using Shear Wave Elastography in Comparison to FibroScan and Histology

Keysberg, Leonie

The ferroptosis mediator ACSL4 fails to prevent disease progression in mouse models of MASLD
Cross-cellular interactions between hepatocytes and cholangiocytes: The role of NF-κB pathways in hepatocarcinogenesis

Khaled, Najib Ben

PD-L1 expressing circulating tumor cells to predict survival in patients with advanced hepatocellular carcinoma treated with immunotherapy: a prospective, multicenter study
Predictive Value of Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte ratio in Advanced Hepatocellular Carcinoma Treated with Sorafenib Monotherapy or Combined with Radioembolization
Adiposity and myosteatosis are prognostic biomarkers in advanced HCC patients receiving immunotherapy
Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte

Kierderof, Katrin

Impaired liver regeneration in obesity is driven by IFNAR signaling in Kupffer cells

Kilian, Christoph

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Killer, Alexander

High proportion of complicated treatment courses in patients with chronic hepatitis E infection: Men and older patients may have higher risk for viral relapse, real life data from single centre
Two cases of hepatic lues demonstrating the highly variable presentation of syphilis

Kimm, Melanie

Predictive Value of Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte ratio in Advanced Hepatocellular Carcinoma Treated with Sorafenib Monotherapy or Combined with Radioembolization
Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer
Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer

Kimmann, Markus

Kurzfristige Mortalität und Diagnose von ACLF wird durch TIPS bei hydropischer Dekompensation aufgehoben: Eine Fall-Kontroll-Studie

Kindler, E. M.

Abstract for section “Clinical Hepatology, Surgery, LTX”

King, Thomas

Liver enzymes reductions from baseline over time in resmetirom treated patients in a Phase 3 study, MAESTRO-NASH

Kiraithe, Muthamia

Skewed HBV-specific CD8+T cell repertoire in chronic versus acute-resolving HBV infection

Klebingat, Fabienne

Interaktion zwischen metabolischen Faktoren und Genetik am Beispiel Alpha-1-Antitrypsin-Mangel

Kleigrewe, Karin

The anti-tumour effector function of mucosal-associated invariant T cells against hepatocellular carcinoma is impaired by fatty acids and aberrant lipid metabolism

Klein, Sabine

Die Entstehung von ACLF ist mit einer geschlechtsunabhängigen Reduktion des Verbrauches von Leptin in der Leber assoziiert
Die geschlechtsspezifische Regulation des Estradiol-Signalwegs in der portalen Hypertension

Kleinlein, Hannah

Multimodal assessment of the skin-nerve-axis identifies specific patterns in patients with cholestatic liver disease-associated pruritus

Klindt, Caroline

Incidence and risk factors of DILI in Ethiopian patients receiving tuberculosis treatment – do polymorphisms of hepatic transporter proteins play a role?

Klindt-Morgan, Caroline

Health related quality of life (HRQoL) in patients Metabolic dysfunction-associated steatotic liver disease (MASLD)

Klingenspor, Martin

Association of the PNPLA3 p.I148M common variant with increased resting energy expenditure in the context of cold adaptation in humans

Klingmüller, Ursula

The role of sex-specific mitochondrial changes in the pathogenesis of fatty liver disease
Dynamics of disease progression and regeneration in a multiscale liver model
Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency

Klinker, Hartwig

Previous hepatitis B virus infection and the risk of liver-related complications in patients after HCV cure – Data on more than 6000 patients from the German Hepatitis C-Registry (DHC-R)
Overweight, but not alcohol is associated with increased risk for advanced liver disease in patients with chronic hepatitis C infection- results from the German Hepatitis C-Registry (DHC-R)

Kluge, Martin

Evaluation of tacrolimus and mycophenolate mofetil as second-line therapy in autoimmune hepatitis – real-world data from the Charité Berlin cohort

Kluwe, Johannes

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage

Knoefel, Wolfram

The Impact of Perioperative Infections on Long-Term Survival After Liver Resection for Hepatocellular Carcinoma and Cholangiocellular Carcinoma: A Retrospective Analysis

Knolle, Percy

Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection
Impaired liver regeneration in obesity is driven by IFNAR signaling in Kupffer cells
The pivotal role of infected hepatocytes in determining the outcome of antiviral CD8 T cell immunity in the liver
The anti-tumour effector function of mucosal-associated invariant T cells against hepatocellular carcinoma is impaired by fatty acids and aberrant lipid metabolism
Molecular pathways defining human CD8 T cell auto-aggression in immune-mediated liver diseases
Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC
Immunoregulation and MDSC-Mediated T Cell Paralysis in Hepatocellular Carcinoma Following rVSV-NDV Therapy
A liver-tissue rheostat limits T cell receptor signaling and impairs function of virus-specific CD8 T cells in chronic viral hepatitis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Knopp, Lisa

Genetic Variant Analysis in Low Phospholipid-Associated Cholelithiasis Patients through Whole Exome Sequencing

Ko, Chunkyu

Identification of amino acids restricting HBV receptor function in porcine NTCP

Koch, Alexander

HOPE treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation

Koch, Chiara

Optimizing Piperacillin/Tazobactam Dosing in ACLF Patients through Interprofessional Therapeutic Drug Monitoring

Kocheise, Lorenz

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

Koehler, Jan Philipp

First successful pregnancies in patients with cerebrotendinous xanthomatosis treated with chenodeoxycholic acid in Germany
ASMD (acid sphingomyelinase deficiency), formerly Morbus Niemann-Pick type A/B: four adult cases with idiopathic hepatosplenomegaly and first results from enzyme replacement therapy (ERT) with olipudase alfa

Kohlhepp, Marlene

Unveiling Cellular Heterogeneity and Liver Pathophysiology in Liver Transplant Recipients through Multiplex Image Analysis
Inhibition of the chemokine CXCL12 promotes liver cancer progression by modulating the inflammatory and angiogenic tumor microenvironment

Kohnke-Ertel, Birgit

Cell type-specific role of CD44 in liver regeneration

Köhrer, Karl

TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs

Kohsar, Matin

Analysis of the CXCL9-11 mediating recruitment of CXCR3+CD4 T cells to HDV-infected livers

Kolligiannis, Dionysios

RNA profiling and respiratory measurements of liver tissue reveals profound hepatic mitochondrial dysfunction in patients with acute-on-chronic liver failure
Modeling Ischemic-Type Biliary Lesions in Human Cholangiocyte Organoids

Kondylis, Evangelos

Cross-cellular interactions between hepatocytes and cholangiocytes: The role of NF-κB pathways in hepatocarcinogenesis
NF-κB reactivation in TAK1LPC-KO mice induces lethal cholemic nephropathy

Konstantis, Georgios

Effekt der IL-17-Interleukin-Familie auf die Blutgerinnung bei Patienten mit akut dekompensierter Leberzirrhose, bewertet mittels Restricted Cubic Splines

Koop, Paul-Henry

Multimodal characterization of autoimmune hepatitis morbidity and metabolic phenotype
Live(r) and Let Live: Combining AI and Citizen Science in Hepatology
Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank
Predicting Controlled Attenuation Parameter and Elastographic Modulus from Handheld Ultrasound Device Data using Machine Learning
Machine learning can predict advanced but not early liver disease on brain MRI

Koppe, Christiane

The ferroptosis mediator ACSL4 fails to prevent disease progression in mouse models of MASLD

Korangy, Firouzeh

Activating Mucosal-Associated Invariant T (MAIT) cells for next generation immunotherapy of liver cancer

Körner, Christiane

The role of sex-specific mitochondrial changes in the pathogenesis of fatty liver disease
Dynamics of disease progression and regeneration in a multiscale liver model

Kornfehl, Andrea

Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage

Korolewicz, James A.

Characterization of T cell subsets and dynamic remodeling following immune checkpoint inhibition in hepatocellular carcinoma

Kosinska, Anna

Silencing of HBV and PD-L1 synergistically enhances the efficacy of therapeutic vaccination in high-titer HBV carrier mice
Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection

Kotsiliti, Elena

Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx
Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Kött, Julian

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

Kowalczyk, Manuela

Absence of cholesterol gallstone formation in male C57BL/6 mice by abrogation of hepatic thyroid hormone action
Abrogation of Hepatic TRβ Action Protects the Liver from Acute Liver Injury

Kowdley, Kris

Baseline Characteristics and Risk Profiles of 1111 Patients With Primary Biliary Cholangitis (PBC) in Need of Second-Line Therapy

Kraft, Anke

Granzyme profiles in CXCR6+PD-1+CD8+T cells differentiate acute and chronic hepatitis flares and may reflect intrahepatic immune imprints
Immune activation as a hallmark in liver disease progression
Cytotoxic CD16+γδ T Cells Are Associated with Virus Control in Chronic Hepatitis B Virus (HBV) Infection by Mediating Antibody-Dependent Cellular Cytotoxicity (ADCC)
Unterschiedliche Cluster des intestinalen Mikrobioms bei fortgeschrittener Leberzirrhose korrelieren mit Antibiotikabehandlung, Störungen der Darmbarriere und systemischer Inflammation
Myeloid reprogramming of T cells: a mechanism to maintain peritoneal homeostasis
Non-Selective Beta Blockers Reduce Inflammatory Bystander CD8+T Cell Activation in Decompensated Cirrhosis

Krag, Aleksander

Unique histological liver phenotype in children and adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype)
Interaktion zwischen metabolischen Faktoren und Genetik am Beispiel Alpha-1-Antitrypsin-Mangel

Kratzer, Alexander

Optimizing Piperacillin/Tazobactam Dosing in ACLF Patients through Interprofessional Therapeutic Drug Monitoring

Krautgartner, Dominik

HOPE treatment prior to organ transplant alters key immune modulators in patients receiving liver transplantation

Krawczyk, Marcin Jan

Identification of new potential genetic risk factors for cholestasis and gallstone disease: report of three-generation family with cholestatic phenotype
Do genetic variants modulate liver injury in patients with diabetes mellitus? – results of a prospective, single center study

Krebs, Christian F.

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Kreiner, Philipp

Efficacy of Software-Based Analysis of Mouse Liver Samples to Assess Cell Death
Gender-specific development of liver injury and necroinflammation over time after hepatic ischaemia-reperfusion in a mouse model
Using X-Ray Microscopy to Visualize 3D Architecture of Native Spheroid and Organoid Samples

Kremer, Andreas E

Multimodal assessment of the skin-nerve-axis identifies specific patterns in patients with cholestatic liver disease-associated pruritus
Interaktion zwischen metabolischen Faktoren und Genetik am Beispiel Alpha-1-Antitrypsin-Mangel

Kremer, Andreas E.

Liver Transplantation after Immune Checkpoint Inhibition in HCC Patients: Insights from an International Multicenter Registry
Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial
Baseline Characteristics and Risk Profiles of 1111 Patients With Primary Biliary Cholangitis (PBC) in Need of Second-Line Therapy

Kronenberg, Katharina

Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis
Angiopoietin-1 Receptor (CD202b) Identifies IL-4-secreting Human Invariant Natural Killer Cells

Krus, Frederike

Die Entstehung von ACLF ist mit einer geschlechtsunabhängigen Reduktion des Verbrauches von Leptin in der Leber assoziiert

Krzikalla, Daria

Tolerance induction by liver sinusoidal endothelial cells is preserved in liver fibrosis

Kubitz, Phil

Association of the PNPLA3 p.I148M common variant with increased resting energy expenditure in the context of cold adaptation in humans

Kubitz, Ralf

Assessment of Liver Fibrosis using Shear Wave Elastography in Comparison to FibroScan and Histology

Kubitza, Marion

ALR induces EGF-receptor transactivation and impairs classical IL-6 signaling by activation of sheddase ADAM17

Kücükoglu, Özlem

Towards Establishing L-Ornithine-L-Aspartate as a Potential Basic Medication for Metabolic Dysfunction-associated Steatotic Liver Disease

Kudo, Masatoshi

Five-year overall survival (OS) and OS by tumour response measures from the Phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)

Kuesgens, Lena

NF-κB reactivation in TAK1LPC-KO mice induces lethal cholemic nephropathy

Kühnel, Florian

Epitope-flanking amino acid substitutions facilitate enhanced antigen processing and improve anti-tumoral T cell immunity
Investigation of CD4 T cell help and MHC II in therapeutic vaccinations against liver cancer

Kuiper, Melvin

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Kuipers, Sonja

Dynamic changes in macrophage populations in MASLD and its influence on prostaglandin E2-mediated signaling

Kumthekar, Aditi

Epitope-flanking amino acid substitutions facilitate enhanced antigen processing and improve anti-tumoral T cell immunity

Kuna, Manuela

Dynamic changes in macrophage populations in MASLD and its influence on prostaglandin E2-mediated signaling

Kunst, Claudia

Targeting p53 Isoforms: A Novel Approach for Anticancer Therapy
Organ Donation from Patients with Child-Pugh Class C Cirrhosis: A Clinical Feasibility or Ethical Dilemma?
Liver Cirrhosis as a Risk Factor for Gut Ischemia in the Intensive Care Unit
Intestinal Barrier Disruption in Liver Cirrhosis: Bacteria-mediated Cell Junction Degradation and p53-Mediated Paraptosis in Spontaneous Bacterial Peritonitis
A Biliary Organoid Approach to Study the Transition from Primary Sclerosing Cholangitis to Cholangiocarcinoma

Kupke, Paul

Soluble CD46 as a diagnostic biomarker for steatotic liver disease
Angiopoietin-1 Receptor (CD202b) Identifies IL-4-secreting Human Invariant Natural Killer Cells

Kurschatke, Leon

High expression of SLIT2 in intrahepatic cholangiocarcinoma stroma