Abstracts (HTML) List of Authors

Labriola, Dominic

Liver enzymes reductions from baseline over time in resmetirom treated patients in a Phase 3 study, MAESTRO-NASH

Lachaux, Alain

Unique histological liver phenotype in children and adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype)

Laevens, Benjamin

Live(r) and Let Live: Combining AI and Citizen Science in Hepatology
Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank
Machine learning identifies microbiome associations with MASLD biomarkers
Machine learning can predict advanced but not early liver disease on brain MRI

Lahmer, Tobias

Therapeutic plasma exchange in patients with acute on chronic liver failure and severe coagulation disorder: a case series

Lambert, Henriette

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Lambert, Irina

Identification of new potential genetic risk factors for cholestasis and gallstone disease: report of three-generation family with cholestatic phenotype
Do genetic variants modulate liver injury in patients with diabetes mellitus? – results of a prospective, single center study

Lammert, Frank

Identification of new potential genetic risk factors for cholestasis and gallstone disease: report of three-generation family with cholestatic phenotype

Lampertico, Pietro

Improvement in liver histology is observed in most patients with chronic hepatitis delta after 48 weeks of bulevirtide monotherapy

Lang, Judith

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Lang, Karl

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Lang, Philipp

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Lange, Christian M.

Improved Mortality Risk Stratification in Decompensated Liver Cirrhosis and Acute-On-Chronic Liver Failure Using the Updated KDIGO AKI Criteria
Effects of sodium-linked glucose transporter 2 inhibitors in liver transplant recipients with impaired renal function
The vitamin D receptor genotype is associated with Vitamin D- and Interleukin-6 concentrations in liver cirrhosis and acute-on-chronic liver failure
Interleukin-22 (IL-22) is associated with progression to Acute-on-Chronic Liver Failure (ACLF) and short-term mortality in cirrhosis
Downregulation of interleukine-6 receptors on ascitic T cells may shape the immune compartment in the peritoneal cavity
Excessive production and cleavage of fibroblast growth factor 23 in decompensated cirrhosis: pathophysiological and clinical implications
Liver Transplantation after Immune Checkpoint Inhibition in HCC Patients: Insights from an International Multicenter Registry
RNA profiling and respiratory measurements of liver tissue reveals profound hepatic mitochondrial dysfunction in patients with acute-on-chronic liver failure
Modeling Ischemic-Type Biliary Lesions in Human Cholangiocyte Organoids
Absence of cholesterol gallstone formation in male C57BL/6 mice by abrogation of hepatic thyroid hormone action
Abrogation of Hepatic TRβ Action Protects the Liver from Acute Liver Injury

Lange, Sebastian

Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx

Langenbacher, Diane

Symptom Self-Reporting in PBC: Consolidated results of a Mobile App Approach

Langer, Mona

Improved Mortality Risk Stratification in Decompensated Liver Cirrhosis and Acute-On-Chronic Liver Failure Using the Updated KDIGO AKI Criteria
The vitamin D receptor genotype is associated with Vitamin D- and Interleukin-6 concentrations in liver cirrhosis and acute-on-chronic liver failure
Interleukin-22 (IL-22) is associated with progression to Acute-on-Chronic Liver Failure (ACLF) and short-term mortality in cirrhosis
Downregulation of interleukine-6 receptors on ascitic T cells may shape the immune compartment in the peritoneal cavity
Excessive production and cleavage of fibroblast growth factor 23 in decompensated cirrhosis: pathophysiological and clinical implications
Modeling Ischemic-Type Biliary Lesions in Human Cholangiocyte Organoids

Langer, Mona-May

RNA profiling and respiratory measurements of liver tissue reveals profound hepatic mitochondrial dysfunction in patients with acute-on-chronic liver failure

Lang-Meli, Julia

Skewed HBV-specific CD8+T cell repertoire in chronic versus acute-resolving HBV infection

Laschinger, Melanie

The pivotal role of infected hepatocytes in determining the outcome of antiviral CD8 T cell immunity in the liver
Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC
ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Laschtowitz, Alena

Evaluation of tacrolimus and mycophenolate mofetil as second-line therapy in autoimmune hepatitis – real-world data from the Charité Berlin cohort
Single-nuclei RNA-sequencing of human liver samples reveals heterogeneity and compositional changes of biliary epithelial cell subpopulations during the progression of primary sclerosing cholangitis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Lau, Audrey

Improvement in liver histology is observed in most patients with chronic hepatitis delta after 48 weeks of bulevirtide monotherapy
Bulevirtide in combination with pegylated interferon alfa-2a shows a sustained off-treatment response in the liver

Lau, George

Five-year overall survival (OS) and OS by tumour response measures from the Phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)

Lautwein, Tobias

TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs

Lazic, Ivana

Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial

Lebeaupin, Cynthia

Hepatocarcinogenesis and metabolic control of immunosuppression by ATF6a-driven ER-stress

Leburgue, Angela

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Lehmler, Max

T cell hyporesponsiveness distinguishes Autoimmune Hepatitis from Drug-Induced Liver Injury

Leicht, Hans Benno

Feasibility and Mortality Prediction of Bedside Rectus Femoris Muscle Ultrasound for Sarcopenia Diagnosis in Liver Cirrhosis
Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte
Long-term outcomes of Metabolic dysfunction associated steatotic liver disease (MASLD) patients in a prospective, German real-world cohort

Lemainque, Teresa

Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank

Leone, Valentina

Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx

Levrero, Massimo

Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx

Levy, Cynthia

Safety and efficacy of Upadacitinib in patients with primary sclerosing cholangitis: a multicentre, retrospective study
Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: baseline data from the ongoing Phase 3 GLISTEN (Global Linerixibat Itch STudy of Efficacy and safety iN PBC) trial
Baseline Characteristics and Risk Profiles of 1111 Patients With Primary Biliary Cholangitis (PBC) in Need of Second-Line Therapy

Li, Gang

Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to opposing phenotypes during HFD-induced NASH

Li, Mingyang

Improvement in liver histology is observed in most patients with chronic hepatitis delta after 48 weeks of bulevirtide monotherapy

Li, Siyuan

Stabilin1 mediates ingestion of oxidized erythrocytes by LSECs (efferocytosis)

Li, Wei

First-in-human Clinical Results of a Novel HBV-specific TCR T Cell Therapy (SCG101) in Patients With HBV-related Hepatocellular Carcinoma (HCC)

Li, Xin

Hepatocarcinogenesis and metabolic control of immunosuppression by ATF6a-driven ER-stress

Li, Yujia

Extracellular matrix protein 1 (ECM1) balances liver regeneration by interfering with HGF/c-Met-ERK-MYC and TGF-β-SMAD signaling pathways

Liang, Yaojie

Important roles of HBe and HBs antigens in the evasion of endogenous innate immune responses in Hepatitis B Virus infection

Liebig, Laura

Single-nuclei RNA-sequencing of human liver samples reveals heterogeneity and compositional changes of biliary epithelial cell subpopulations during the progression of primary sclerosing cholangitis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Liedtke, Christian

Rare but there: Novel approaches to discover hepatic mast cell functions in liver fibrosis

Lietzau, Ayesha

Immune activation as a hallmark in liver disease progression
Non-Selective Beta Blockers Reduce Inflammatory Bystander CD8+T Cell Activation in Decompensated Cirrhosis

Lin, Tao

Insulin determines TGF-β-induced epithelial-to-mesenchymal transition through FOXO1 cellular translocation

Lindberg, Eric Lars-Helge

Single-nuclei RNA-sequencing of human liver samples reveals heterogeneity and compositional changes of biliary epithelial cell subpopulations during the progression of primary sclerosing cholangitis

Lindström, Erik

Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy

Ling, Hao

Icer Knockout Influences the Development of Primary Liver Cancer by Promoting Macrophage Infiltration
ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Link, Ralph

Previous hepatitis B virus infection and the risk of liver-related complications in patients after HCV cure – Data on more than 6000 patients from the German Hepatitis C-Registry (DHC-R)

Liu, Hanyang

Inhibition of the chemokine CXCL12 promotes liver cancer progression by modulating the inflammatory and angiogenic tumor microenvironment

Liu, Rui

Insulin determines TGF-β-induced epithelial-to-mesenchymal transition through FOXO1 cellular translocation

Liu, Yuanyuan

Live(r) and Let Live: Combining AI and Citizen Science in Hepatology
Machine Learning Highlights Association of Body Composition with Cholangiocarcinoma Mortality
Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank
Impact of Diabetes and its management on MASLD risk

Liu, Yunpeng

First-in-human Clinical Results of a Novel HBV-specific TCR T Cell Therapy (SCG101) in Patients With HBV-related Hepatocellular Carcinoma (HCC)

Lohmayer, Robert

Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis

Lohse, Ansgar Wilhelm

T cell hyporesponsiveness distinguishes Autoimmune Hepatitis from Drug-Induced Liver Injury
CRISPR/Cas9-mediated Cxcr3 gene knock-out in unstimulated murine primary CD4+T cells
Sarcoidosis of the Liver – An underdiagnosed entity
Analysis of the CXCL9-11 mediating recruitment of CXCR3+CD4 T cells to HDV-infected livers
Tolerance induction by liver sinusoidal endothelial cells is preserved in liver fibrosis
Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab
Low rates of positive evaluation and early liver transplantation (LT) for acute-on-chronic liver failure (ACLF) in a European tertiary referral center
Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases
Expression signatures of IL-18 and IL-18BP characterize stages of cirrhotic decompensation

Londoño, Maria-Carlota

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Longerich, Thomas

A 5:2 intermittent fasting regimen ameliorates MASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
Batch-effect correction improves downstream imaging mass cytometry data quality and facilitates robust cell type identification in the liver and hepatocellular carcinoma microenvironment
Clinical Utility of Metallothionein Immunohistochemistry (MT-IHC) for Early Tissue-based Diagnosis of Wilson Disease (WD)

Loomba, Rohit

Live(r) and Let Live: Combining AI and Citizen Science in Hepatology
Deep learning can predict PNPLA3 I148M homozygous carriers in SLD patients based on MRIs from UK Biobank

Loosen, Sven

The Impact of Perioperative Infections on Long-Term Survival After Liver Resection for Hepatocellular Carcinoma and Cholangiocellular Carcinoma: A Retrospective Analysis
CLEAN-DUCT / TRITICC-3 (IKF070) – A Phase IIa, Prospective, Single-Arm, Open-Label, Non-Randomized, Multi-Center Pilot Study of Durvalumab+Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

Lopez-Anguita, Natalia

Single-nuclei RNA-sequencing of human liver samples reveals heterogeneity and compositional changes of biliary epithelial cell subpopulations during the progression of primary sclerosing cholangitis

López-Madrona, Víctor J.

Restricting datasets to classifiable samples allows prediction of immune checkpoint blockade-related hepatitis

Lu, Mengji

Important roles of HBe and HBs antigens in the evasion of endogenous innate immune responses in Hepatitis B Virus infection

Lücke, Jöran

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

Ludwig Lutz, Philipp

Microbial detection in peritonitis may be faster by automated molecular methods, but less sensitive, which also depends on cause of peritonitis

Luebke, Nadine

High proportion of complicated treatment courses in patients with chronic hepatitis E infection: Men and older patients may have higher risk for viral relapse, real life data from single centre

Luedde, Tom

Distinct gene pathways and cell types define peribiliary disease states in PSC
High proportion of complicated treatment courses in patients with chronic hepatitis E infection: Men and older patients may have higher risk for viral relapse, real life data from single centre
Disrupting the intracellular MK2/3-TTP interaction reduces inflammation but preserves antiviral mechanisms in CMV infection
Incidence and risk factors of DILI in Ethiopian patients receiving tuberculosis treatment – do polymorphisms of hepatic transporter proteins play a role?
TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs
Artificial Intelligence for differentiation of focal liver lesions using contrast-enhanced ultrasound (CEUS)
The Impact of Perioperative Infections on Long-Term Survival After Liver Resection for Hepatocellular Carcinoma and Cholangiocellular Carcinoma: A Retrospective Analysis
Inhibition of TGFb signalling attenuates surgical liver injury and improves liver regeneration after partial hepatectomy
MLKLK219R Mutation Protects Against Diet-Induced MASLD but is Attenuated by Alcohol Consumption
Two cases of hepatic lues demonstrating the highly variable presentation of syphilis
The ferroptosis mediator ACSL4 fails to prevent disease progression in mouse models of MASLD
First successful pregnancies in patients with cerebrotendinous xanthomatosis treated with chenodeoxycholic acid in Germany
Hepatitis C virus alters hepatocyte’s response to interleukin-1 by modulation of IκBα-mediated signaling
ASMD (acid sphingomyelinase deficiency), formerly Morbus Niemann-Pick type A/B: four adult cases with idiopathic hepatosplenomegaly and first results from enzyme replacement therapy (ERT) with olipudase alfa
Disease stage dependent efficacy of systemic apical sodium dependent bile acid transporter (ASBT) inhibition in mice with cholemic nephropathy
CLEAN-DUCT / TRITICC-3 (IKF070) – A Phase IIa, Prospective, Single-Arm, Open-Label, Non-Randomized, Multi-Center Pilot Study of Durvalumab+Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma
Cross-cellular interactions between hepatocytes and cholangiocytes: The role of NF-κB pathways in hepatocarcinogenesis
NF-κB reactivation in TAK1LPC-KO mice induces lethal cholemic nephropathy

Lurje, Georg

Association of the Genetic Variant VEGFA rs3025039 with Incidence and Prognosis of Cholangiocarcinoma

Lurje, Isabella

Association of the Genetic Variant VEGFA rs3025039 with Incidence and Prognosis of Cholangiocarcinoma

Lütgehetmann, Marc

Analysis of the CXCL9-11 mediating recruitment of CXCR3+CD4 T cells to HDV-infected livers
Duration and clinical relevance of viral shedding of HEV by the stool: results from an observational prospective study

Lüttgen, Dominik

Scherwellenelastografie übertrifft Fibroscan bei der Detektion von höhergradigen Ösophagusvarizen
Entwicklung eines klinischen Entscheidungsbaums für die nicht-invasive Diagnostik der Transplantat-Steatose bei Patienten nach Lebertransplantation

Lyu, Huanran

Stabilin1 mediates ingestion of oxidized erythrocytes by LSECs (efferocytosis)