Abstracts (HTML) List of Authors

Wagner, Jonas

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Waisman, Ari

Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis

Waldschmidt, Dirk

CLEAN-DUCT / TRITICC-3 (IKF070) – A Phase IIa, Prospective, Single-Arm, Open-Label, Non-Randomized, Multi-Center Pilot Study of Durvalumab+Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

Walkenhaus, Michelle

Interaktion zwischen metabolischen Faktoren und Genetik am Beispiel Alpha-1-Antitrypsin-Mangel

Walker, Andreas

High proportion of complicated treatment courses in patients with chronic hepatitis E infection: Men and older patients may have higher risk for viral relapse, real life data from single centre
Skewed HBV-specific CD8+T cell repertoire in chronic versus acute-resolving HBV infection

Wallin, Jeffrey J.

Bulevirtide in combination with pegylated interferon alfa-2a shows a sustained off-treatment response in the liver

Walmsley, Martine

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Walter, Franziska

Single Shot Liver: MR-guided stereotactic body radiotherapy (SBRT) for hepatic malignancies and metastasis

Wan, Shan

The cell polarity protein MPP5/PALS1 controls the subcellular localization of the oncogenes YAP and TAZ in hepatocellular carcinoma

Wan, Xueshuai

First-in-human Clinical Results of a Novel HBV-specific TCR T Cell Therapy (SCG101) in Patients With HBV-related Hepatocellular Carcinoma (HCC)

Wang, Baocai

Brg1 suppress DEN-induced hepatocellular carcinogenesis in mice

Wang, Hua

Insulin determines TGF-β-induced epithelial-to-mesenchymal transition through FOXO1 cellular translocation

Wang, Jianye

ATF3 modulates the extracellular microenvironment and inflammation pathways, protecting the mouse liver from carbon tetrachloride (CCl4)-induced fibrosis

Wang, Jie

Deciphering the Role of LSD1 in Hepatocellular Carcinoma: Implications for Cell Proliferation and Energy Homeostasis

Wang, Lingyu

Deciphering the Role of LSD1 in Hepatocellular Carcinoma: Implications for Cell Proliferation and Energy Homeostasis

Wang, Sai

Extracellular matrix protein 1 (ECM1) balances liver regeneration by interfering with HGF/c-Met-ERK-MYC and TGF-β-SMAD signaling pathways

Wang, Ying

Genomic Alterations and Tumor Immune Microenvironment as Predictors of Immunotherapy Outcomes in Advanced Biliary Tract Cancer

Ward, Caroline

Characterization of T cell subsets and dynamic remodeling following immune checkpoint inhibition in hepatocellular carcinoma

Warnatz, Klaus

Ultrasound and Elastography for Detection of Portal Hypertension in Common Variable Immunodeficiency

Weber, Achim

Cellular cytokinesis, hyperplasia and hypertrophy define critical phases for liver regeneration efficiency

Weber, Julius

The anti-tumour effector function of mucosal-associated invariant T cells against hepatocellular carcinoma is impaired by fatty acids and aberrant lipid metabolism
Mucosal-associated invariant T (MAIT) cells possess direct anti-tumour potential, but are rendered dysfunctional within the tumour microenvironment in HCC

Weber, Sabine

Effects of sodium-linked glucose transporter 2 inhibitors in liver transplant recipients with impaired renal function

Weber, Susanne

Identification of new potential genetic risk factors for cholestasis and gallstone disease: report of three-generation family with cholestatic phenotype
Do genetic variants modulate liver injury in patients with diabetes mellitus? – results of a prospective, single center study

Wedemeyer, Heiner

Previous hepatitis B virus infection and the risk of liver-related complications in patients after HCV cure – Data on more than 6000 patients from the German Hepatitis C-Registry (DHC-R)
Improvement in liver histology is observed in most patients with chronic hepatitis delta after 48 weeks of bulevirtide monotherapy
Granzyme profiles in CXCR6+PD-1+CD8+T cells differentiate acute and chronic hepatitis flares and may reflect intrahepatic immune imprints
Immune activation as a hallmark in liver disease progression
Bulevirtide in combination with pegylated interferon alfa-2a shows a sustained off-treatment response in the liver
Identifizierung und Validierung eines idealen PSG-Reduktionskorridors zur optimalen Asziteskontrolle bei Minimierung des HE-Risikos nach TIPS-Anlage
Value of plasma ammonia levels to predict hepatic encephalopathy after transjugular intrahepatic portosystemic shunt insertion
Reduzierte Inzidenz von Peritonitis und verringerte Explantationsrate durch Beimengung von Silberpartikeln bei getunnelten Peritonealkathetern bei Patient*innen mit refraktärem Aszites
Unterschiedliche Cluster des intestinalen Mikrobioms bei fortgeschrittener Leberzirrhose korrelieren mit Antibiotikabehandlung, Störungen der Darmbarriere und systemischer Inflammation
Comparison of histological and non-invasive assessment of significant fibrosis in a multicenter cohort of MASLD patients
Epitope-flanking amino acid substitutions facilitate enhanced antigen processing and improve anti-tumoral T cell immunity
Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx
Non-Selective Beta Blockers Reduce Inflammatory Bystander CD8+T Cell Activation in Decompensated Cirrhosis
Overweight, but not alcohol is associated with increased risk for advanced liver disease in patients with chronic hepatitis C infection- results from the German Hepatitis C-Registry (DHC-R)
Investigation of CD4 T cell help and MHC II in therapeutic vaccinations against liver cancer

Wehmeyer, Malte

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Wei, Teng

The cell polarity protein MPP5/PALS1 controls the subcellular localization of the oncogenes YAP and TAZ in hepatocellular carcinoma

Weiand, Matthias

Korrektur der Morbus Wilson Punktmutation H1069Q in iPSCs mittels CRISPR/Cas9 Genom-Editierung

Weich, Alexander

Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte

Weidemann, Sören Alexander

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Weigle, Clara

Cytokine adsorption during normothermic machine perfusion of porcine livers

Weikl, Carolin

Alkaline phosphatase and bilirubin as predictors of long-term outcomes in primary biliary cholangitis: A systematic literature review

Weiler, Sofia

The cell polarity protein MPP5/PALS1 controls the subcellular localization of the oncogenes YAP and TAZ in hepatocellular carcinoma

Weiler-Normann, Christina

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Weinmann, Arndt

Comparative evaluation of standard machine learning models for liver fibrosis detection
Liver Transplantation after Immune Checkpoint Inhibition in HCC Patients: Insights from an International Multicenter Registry

Weiskirchen, Ralf

Rare but there: Novel approaches to discover hepatic mast cell functions in liver fibrosis

Weiss, Thomas

Cell type specific decoding of TGF-β2 production, signaling and outcome in the dynamics of cholestatic liver disease

Weiß, Marc

Interleukin-22 (IL-22) is associated with progression to Acute-on-Chronic Liver Failure (ACLF) and short-term mortality in cirrhosis
Downregulation of interleukine-6 receptors on ascitic T cells may shape the immune compartment in the peritoneal cavity
Excessive production and cleavage of fibroblast growth factor 23 in decompensated cirrhosis: pathophysiological and clinical implications

Weiß, Thomas S.

ALR induces EGF-receptor transactivation and impairs classical IL-6 signaling by activation of sheddase ADAM17

Weissenborn, Karin

Value of plasma ammonia levels to predict hepatic encephalopathy after transjugular intrahepatic portosystemic shunt insertion

Weltzsch, Jan Philipp

New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Wendler-Link, Lena

LZTR1 acts as a potent tumor suppressor gene in liver cancer by safeguarding aberrant MAPK activity via posttranslational control of RAS GTPases

Weng, Honglei

Genomic Alterations and Tumor Immune Microenvironment as Predictors of Immunotherapy Outcomes in Advanced Biliary Tract Cancer
Extracellular matrix protein 1 (ECM1) balances liver regeneration by interfering with HGF/c-Met-ERK-MYC and TGF-β-SMAD signaling pathways
Insulin determines TGF-β-induced epithelial-to-mesenchymal transition through FOXO1 cellular translocation
TGF-β-SMAD axis plays an essential role in the regulation of LPC proliferation and performing hepatocyte function in acute liver failure

Wenzel, Jürgen J.

Soluble CD46 as a diagnostic biomarker for steatotic liver disease

Werner, Jens

Soluble CD46 as a diagnostic biomarker for steatotic liver disease
Angiopoietin-1 Receptor (CD202b) Identifies IL-4-secreting Human Invariant Natural Killer Cells

Werner, Jill

HBsAg-specific CD4 T cell response in HBV vaccinated individuals
No evidence for viral escape mutations in immunodominant CD4 HCV-specific epitopes

Wernsdorfer, Annika

Identifying Risk Factors for Secondary Sclerosing Cholangitis in Critically Ill Patients: A Retrospective Analysis of ICU-Associated Variables

Westermann, Dirk

Right ventricular contractility predicts clearance of ascites after transjugular intrahepatic portosystemic shunt (TIPS)

Wettengel, Jochen

Identification of amino acids restricting HBV receptor function in porcine NTCP

Wiedemann, Gabriela

Influence of the Chemerin signaling pathway on NK cell function and migration
The anti-tumour effector function of mucosal-associated invariant T cells against hepatocellular carcinoma is impaired by fatty acids and aberrant lipid metabolism

Wieman, Bengt

Cytokine adsorption during normothermic machine perfusion of porcine livers

Wiering, Leke

Evaluation of tacrolimus and mycophenolate mofetil as second-line therapy in autoimmune hepatitis – real-world data from the Charité Berlin cohort

Wiesch, Julian zur

Analysis of the CXCL9-11 mediating recruitment of CXCR3+CD4 T cells to HDV-infected livers

Wiethoff, Hendrik

Clinical Utility of Metallothionein Immunohistochemistry (MT-IHC) for Early Tissue-based Diagnosis of Wilson Disease (WD)

Wiggers, Samiel

Assessment of Liver Fibrosis using Shear Wave Elastography in Comparison to FibroScan and Histology

Wildgruber, Moritz

PD-L1 expressing circulating tumor cells to predict survival in patients with advanced hepatocellular carcinoma treated with immunotherapy: a prospective, multicenter study
Circulating tumor cells predict recurrence risk in early HCC treated with local ablative therapy
Predictive Value of Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte ratio in Advanced Hepatocellular Carcinoma Treated with Sorafenib Monotherapy or Combined with Radioembolization
Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer

Wilhelm, Laura Muana

Previous hepatitis B virus infection and the risk of liver-related complications in patients after HCV cure – Data on more than 6000 patients from the German Hepatitis C-Registry (DHC-R)

Wilhelm Lohse, Ansgar

Circulating matricellular fibrosis markers TSP2, IGFBP7, TSP4 and the M2-macrophage marker CD163 in predicting disease stage and progression in primary sclerosing cholangitis
New treatment targets in autoimmune hepatitis: detection using integrative omics and target validation in a proof of concept phase II clinical trial

Willemse, José

Exploring the Role of Social Determinants of Health in autoimmune liver disease – a pilot study within the European Reference Network on hepatological diseases

Willuweit, Katharina

Effekt der IL-17-Interleukin-Familie auf die Blutgerinnung bei Patienten mit akut dekompensierter Leberzirrhose, bewertet mittels Restricted Cubic Splines

Wintersteller, Hannah

Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection
A liver-tissue rheostat limits T cell receptor signaling and impairs function of virus-specific CD8 T cells in chronic viral hepatitis

Wirth, Thomas

Epitope-flanking amino acid substitutions facilitate enhanced antigen processing and improve anti-tumoral T cell immunity
Investigation of CD4 T cell help and MHC II in therapeutic vaccinations against liver cancer

Wirth, Victoria

Schistosoma mansoni egg-derived antigens stimulate metabolic activity in the liver and colon by engaging insulin-like growth factor-1 receptor signaling pathways

Wirtz, Theresa Hildegard

In-depth histological evaluation and comparison of mouse models for cholangiocarcinoma studies

Wischer, Lara

Batch-effect correction improves downstream imaging mass cytometry data quality and facilitates robust cell type identification in the liver and hepatocellular carcinoma microenvironment

Wisskirchen, Karin

First-in-human Clinical Results of a Novel HBV-specific TCR T Cell Therapy (SCG101) in Patients With HBV-related Hepatocellular Carcinoma (HCC)
Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx
Generation and functional analysis of spacer-modified HBV-specific chimeric antigen receptors

Woelfl, Stefan

Linker Phosphorylation of Smad3 as a Driver of Cholangiocarcinoma Progression and Chemotherapy Resistance

Wohlleber, Dirk

Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection
The pivotal role of infected hepatocytes in determining the outcome of antiviral CD8 T cell immunity in the liver
A liver-tissue rheostat limits T cell receptor signaling and impairs function of virus-specific CD8 T cells in chronic viral hepatitis

Wolf, Katharina

Efficacy of Software-Based Analysis of Mouse Liver Samples to Assess Cell Death
Gender-specific development of liver injury and necroinflammation over time after hepatic ischaemia-reperfusion in a mouse model

Wolf, Stephanie D.

Disrupting the intracellular MK2/3-TTP interaction reduces inflammation but preserves antiviral mechanisms in CMV infection
TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs
Inhibition of TGFb signalling attenuates surgical liver injury and improves liver regeneration after partial hepatectomy

Wolfertz, Julia

Adiposity and myosteatosis are prognostic biomarkers in advanced HCC patients receiving immunotherapy

Wolff, Timo

Analysis of mitotic stress-induced activation of the cGAS/STING signaling pathway in human hepatocytes

Wolski, Annika

Duration and clinical relevance of viral shedding of HEV by the stool: results from an observational prospective study

Woltemate, Sabrina

Unterschiedliche Cluster des intestinalen Mikrobioms bei fortgeschrittener Leberzirrhose korrelieren mit Antibiotikabehandlung, Störungen der Darmbarriere und systemischer Inflammation

Worthmann, Anna

Intrahepatic T cell responses modulate thermogenic adaptation in adipose tissues

Wu, Wei

First-in-human Clinical Results of a Novel HBV-specific TCR T Cell Therapy (SCG101) in Patients With HBV-related Hepatocellular Carcinoma (HCC)

Wulf, Sophie

Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

Wunsch, Hannah

Factor VIII/protein C ratio predicts post-TIPS transplantation-free survival
Right ventricular contractility predicts clearance of ascites after transjugular intrahepatic portosystemic shunt (TIPS)

Wurmser, Christine

Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection