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Exp Clin Endocrinol Diabetes 2021; 129(05): 390-395
DOI: 10.1055/a-0892-4290
Article

The Relationship Between Visceral Adiposity Index and Epicardial Adipose Tissue in Patients with Type 2 Diabetes Mellitus

Ismail Baloglu
1   Department of Internal Medicine, Division of Nephrology, Necmettin Erbakan University Meram School of Medicine, Turkey
,
Kultigin Turkmen
1   Department of Internal Medicine, Division of Nephrology, Necmettin Erbakan University Meram School of Medicine, Turkey
,
Nedim Yılmaz Selcuk
1   Department of Internal Medicine, Division of Nephrology, Necmettin Erbakan University Meram School of Medicine, Turkey
,
Halil Zeki Tonbul
1   Department of Internal Medicine, Division of Nephrology, Necmettin Erbakan University Meram School of Medicine, Turkey
,
Adalet Ozcicek
2   Department of Internal Medicine, Erzincan University, Mengucek Gazi Training and Research Hospital, Turkey
,
Hikmet Hamur
3   Department of Cardiology, Erzincan University, Mengucek Gazi Training and Research Hospital, Turkey
,
Sinan Iyısoy
4   Department of Statistics, Necmettin Erbakan University Meram School of Medicine, Turkey
,
Emin Murat Akbas
5   Department of Endocrinology, Erzincan University, Mengucek Gazi Training and Research Hospital, Turkey
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Abstract

Introduction and aim Cardiovascular diseases remain the most common cause of morbidity and mortality in patients with diabetes. Epicardial adipose tissue (EAT), visceral fat depot of the heart, was found to be associated with coronary artery disease in cardiac and non-cardiac patients. Increased visceral adiposity is associated with proinflammatory activity, impaired insulin sensitivity, increased risk of atherosclerosis and high mortality. In the present study we aimed to investigate the relationship between EAT and visceral adiposity index (VAI) in patients with diabetes.

Methods This was a cross-sectional study involving 128 patients with type 2 diabetes mellitus (73 females, 55 males; mean age, 54.09+±+9.17 years) and 32 control subjects (23 females, 9 males; mean age, 50.09+±+7.81 years). EAT was measured by using a trans-thoracic echocardiograph. Parameters such as waist circumference (WC), body mass index (BMI), triglyceride and high density lipoprotein (HDL) cholesterol were used to calculate VAI.

Result EAT and VAI measurements were significantly higher in patients with diabetes when compared to control subjects. In the bivariate correlation analysis, VAI was positively correlated with uric acid level (r=0.214, p=0.015), white blood cell count (r= 0.262, p=0.003), platelet count (r=0.223, p=0.011) and total cholesterol levels (r= 0.363, p<0.001). Also, VAI was found to be the independent predictor of EAT.

Conclusion Simple calculation of VAI was found to be associated with increased EAT in patients with type 2 diabetes.

Key words

epicardial adipose tissue - visceral adiposity index - diabetes mellitus


Publication History

Received: 26 October 2018
Received: 02 April 2019

Accepted: 10 April 2019

Article published online:
06 May 2019

© 2019. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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