Author commentary on Zaheer Nabi et al.

Zaheer Nabi et al. Gastroesophageal reflux disease after peroral endoscopic „myotomy is unpredictable, but responsive to proton pump inhibitor therapy: a large, single-center study

Prospective analysis on 167 patients with achalasia treated by peroral endoscopic myotomy. Erosive esophagitis and abnormal acid exposure were present in almost half of patients, although only 29 % had symptoms. Most patients responded to proton pump inhibitors, and no risk factors for the development of gastroesophageal reflux disease were identified.