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J Neurol Surg B Skull Base
DOI: 10.1055/a-2627-3969
Original Article

Endoscopic Endonasal Dacryocystectomy for Tumors Involving the Nasolacrimal Duct and Lacrimal Sac

Lifeng Li    *
1   Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China
,
Weiwei Wang   *
1   Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China
2   Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Anhui Medical University, Anhui, People's Republic of China
,
Nyall R. London Jr.
3   Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, United States
,
Tianhua Yi
4   Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Shaoyang University, Hunan, People's Republic of China
,
Yonggang Jin
5   Department of Otolaryngology-Head and Neck Surgery, Xianghe People's Hospital, Hebei, People's Republic of China
,
Xiahong Chen
1   Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China
› Institutsangaben
Funding This study was supported by the Beijing Municipal Administration of Hospitals Incubating Program (PX2024008).
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Abstract

Purpose

Endoscopic endonasal dacryocystorhinostomy is performed to treat epiphora in patients with chronic dacryocystitis. However, the potential application of an endonasal dacryocystectomy for malignancies involving the lacrimal system (lacrimal sac and nasolacrimal duct) has not been sufficiently investigated. This study aims to assess the feasibility of an endonasal dacryocystectomy and to investigate its efficacy with clinical case scenarios.

Materials and Methods

An endoscopic endonasal dacryocystectomy was conducted on two cadaveric specimens (four sides). An endonasal dacryocystectomy for tumors involving the lacrimal system was performed in six patients. The feasibility of performing an endonasal dacryocystectomy was assessed on cadaveric dissection, and the efficacy of endonasal dacryocystectomy for patients with involvement of the lacrimal system was evaluated.

Results

Endonasal extirpation of the lacrimal system was feasible on four cadaveric sides. For five patients with sinonasal malignancies (two adenoid cystic carcinoma, one squamous cell carcinoma, two mucosal melanoma) and one with lacrimal sac melanoma, endonasal dacryocystectomy was successfully performed and negative margins achieved in all six patients. One patient harbored postoperative epiphora, no other comorbidities were detected. With an average follow-up of 18 months, no regional recurrence at the lacrimal system was detected.

Conclusion

To perform an endoscopic endonasal dacryocystectomy is feasible on cadaveric specimens. For sinonasal malignancies secondary involving the lacrimal system, it is possible to conduct an endonasal resection when the indication is appropriately selected.

Keywords

nasolacrimal duct - lacrimal sac - dacryocystectomy - endonasal - sinonasal malignancies

* Both these authors contributed equally to this manuscript.




Publikationsverlauf

Eingereicht: 12. Februar 2025

Angenommen: 03. Juni 2025

Artikel online veröffentlicht:
18. Juni 2025

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