In recent years, endoscopic ultrasound-guided tissue acquisition (EUS-TA) has become
increasingly common for evaluating focal liver lesions [1]
[2]. However, accessing focal liver lesions from the duodenum remains technically challenging.
Here, we report a case in which EUS-TA for a focal liver lesion was successfully performed
via the duodenum by adjusting the orientation of the echoendoscope under fluoroscopic
guidance.
The patient was a woman in her 60s. Abdominal contrast-enhanced magnetic resonance
imaging revealed a 16-mm lesion in segment 4 of the liver ([Fig. 1]), and EUS-TA was scheduled for diagnostic assessment.
Fig. 1 Abdominal contrast-enhanced magnetic resonance imaging revealed a 16-mm lesion in
segment 4 of the liver (arrow).
A convex-array echoendoscope (GF-UCT260; Olympus Medical Systems, Tokyo, Japan) was
advanced to the duodenal bulb. Initially, the probe was oriented caudally, preventing
visualization of the liver ([Fig. 2]
a). Under fluoroscopic guidance, the probe was directed toward the liver ([Fig. 2]
b). The liver was clearly visualized, and the target lesion was successfully identified
on the EUS image ([Fig. 3]) EUS-TA was performed using a 22-gauge fine-needle biopsy needle (SonoTip TopGain;
Medico’s Hirata, Tokyo, Japan). No procedure-related adverse events occurred ([Video 1]).
Fig. 2 Fluoroscopic imaging showing the convex-array echoendoscope at the duodenal bulb.
a Initially, the probe was oriented caudally, preventing visualization of the liver
(arrow). b Under fluoroscopic guidance, the probe was directed toward the liver (arrow).
Fig. 3 A hyperechoic lesion with a peripheral hypoechoic rim was detected in segment 4 of
the liver (arrow). Endoscopic ultrasound-guided tissue acquisition was performed.
Endoscopic ultrasound-guided tissue acquisition from a focal liver lesion via the
duodenum under fluoroscopic guidance.Video 1
Histopathological analysis confirmed adenocarcinoma ([Fig. 4]). The patient was diagnosed with breast cancer liver metastasis and referred for
systemic chemotherapy.
Fig. 4 Histopathological analysis confirmed adenocarcinoma (hematoxylin and eosin staining,
×100). The patient was diagnosed with breast cancer liver metastasis and referred
for systemic chemotherapy.
Visualization of focal liver lesions from the duodenum using EUS can be technically
challenging. However, adjusting the orientation of the echoendoscope under fluoroscopic
guidance allowed for precise lesion detection. This technique may be particularly
useful for targeting focal liver lesions from the duodenal approach.
Endoscopy_UCTN_Code_TTT_1AS_2AF
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