Zeitschrift für Phytotherapie 2009; 30(5): 216-221
DOI: 10.1055/s-0029-1242922
Forschung
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© Hippokrates Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Indischer Weihrauch (Salai guggal) bei rheumatoider Arthritis und Osteoarthritis

Hermann P.T. Ammon
Further Information

Publication History

Publication Date:
09 November 2009 (online)

Zusammenfassung

Die Anwendung von Extrakten aus dem indischen Weihrauch bei rheumatischen Erkrankungen ist derzeit in Deutschland weitverbreitet. In Tierversuchen wurde eine antiphlogistische/antirheumatische Wirkung dieses Extraktes beschrieben. Bisherige klinische Studien sprechen dafür, dass sich Extrakte aus dem Gummiharz von Boswellia serrata günstig bei rheumatoider Arthritis sowie bei Osteoarthritis auswirken. Allerdings sind die erhobenen Fallzahlen gering und eine Reihe von Studien leidet unter Mängeln. Da Extrakte aus dem indischen Weihrauch arm an Nebenwirkungen sind, sollten klinische Studien gemäß wissenschaftlichem Standard durchgeführt werden, um Sicherheit, Wirksamkeit und Verträglichkeit zu beweisen.

Summary

Indian incense (Salai guggal) for the treatment of rheumatoid arthritis and osteoarthritis Extracts from the gum resin of Boswellia serrata (BSE) have been reported to posses antiphlogistic and antirheumatic effects in animal experiments. These effects are thought to be due to so-called boswellic acids. Boswellic acids have been reported to inhibit factors which are related to the immune system. Clinical studies so far show that BSE have beneficial effects on rheumatoid arthritis and osteoarthritis. Nevertheless the studies have only small numbers of patients and some of the studies have not been carried out according to the present scientific rules. On the other hand, since BSE have only little side effects and the diseases in question are mostly chronic and are treated with drugs possessing a number of adverse effects, further clinical studies with high scientific standards are necessary to finally prove their efficacy and safety.

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Prof. (em.) Dr. Hermann P.T. Ammon

Lehrstuhl Pharmakologie für Naturwissenschaftler

Pharmazeutisches Institut der Universität

Tübingen

Auf der Morgenstelle 8

72076 Tübingen

Email: sekretariat.ammon@uni-tuebingen.de

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