A 73-year-old man, who had a history of thoracic aorta aneurysm and aortic valve replacement
operations 25 years ago and anemia diagnosed 4 years previously who was currently
taking warfarin, propranolol, and iron preparations, presented to the emergency department
with melena and hematemesis. His blood pressure was 90/60 mmHg and his heart rate
was 108 beats per minute. Investigations showed he had hemoglobin (Hb) of 9 g/dL and
an international normalized ratio (INR) of 2.3.
He underwent an upper gastrointestinal endoscopy, which revealed a lesion protruding
to the lumen that was 8 – 10 mm in size and magenta-colored, consistent with a vascular
structure 7 – 8 cm proximal to the cardioesophageal junction ([Fig. 1 a, b]). The procedure was terminated without an endoscopic therapeutic intervention and
the patient was admitted to the intensive care unit.
Fig. 1 Endoscopic appearance in a 73-year-old man with a history of thoracic aorta aneurysm
surgery and aortic valve replacement who presented with melena and hematemesis showing
the azygos vein protruding into the esophageal lumen 7 – 8 cm proximal to the cardioesophageal
junction.
He underwent a computed tomography angiogram (CTA) 7 hours later in the interventional
radiology unit, which showed postoperative changes in the ascending aorta, prominent
azygos and hemiazygos veins, widespread intra-abdominal retroperitoneal venous collaterals,
and web formation at the location of the opening of the inferior vena cava to the
right atrium ([Fig. 2]). Percutaneous thoracic angiography (PTA) showed a marked degree of stenosis between
the vena cava and the right atrium. This was treated by balloon dilation using angioplasty
balloons with diameters of 10 – 25 mm during the same session, with improvement in
the appearance of the stenotic segment and in the pressure gradient ([Fig. 3]). No problems were encountered during the follow-up period and the patient remains
under ongoing follow-up in our outpatient clinic.
Fig. 2 Image taken during the venous phase of computed tomography angiography (CTA) showing
dilatation of the azygos vein, which was protruding through the posterior wall of
the esophagus into the esophageal lumen (red arrow).
Fig. 3 Images taken during percutaneous thoracic angiography (PTA) showing: a a marked degree of stenosis related to the web seen at the atriocaval junction during
imaging of the inferior vena cava; b reflux of contrast into the hemiazygos–azygos venous system during the late phase
and varicosity in the azygos vein; c dilation of the atriocaval web being performed with an angioplasty balloon; d improvement in the stenotic segment following the PTA procedure.
Azygoesophageal fistula is a rare cause of upper gastrointestinal tract bleeding.
Shieh et al. reported a case in which bleeding from an azygoesophageal fistula was
defined and safely occluded by sclerotherapy with Lipiodol [1]. Our report shows that endovascular treatment is a safe and effective treatment
option for azygoesophageal fistulas.
Endoscopy_UCTN_Code_CCL_1AB_2AC_3AG
