A 43-year-old male patient presented with obstructive jaundice. Blood samples showed
total bilirubin 3.1 mg/dL, direct bilirubin 2.0 mg/dL, aspartate aminotransferase
(AST) 261 U/L, alanine transaminase (ALT) 165 U/L, alkaline phosphatase 241 U/L. Coagulation,
hemogram, albumin, and renal function test findings were within the normal range.
Serological testing for hepatitis B and hepatitis C virus was negative. Abdominal
ultrasonography and magnetic resonance imaging revealed situs inversus totalis, and
a thrombosed portal vein with cavernoma, and common bile duct/common hepatic duct
(CBD/CHD) obstruction.
Endoscopic retrograde cholangiopancreatography (ERCP) was performed with only minor
changes to the standard technique, as highlighted in previous case reports [1]
[2]. Keeping the patient in the prone position (as used at our institution for ERCP
in patients without situs inversus totalis), the endoscope short position was achieved
by torquing the scope 180 degrees anticlockwise and the papilla was cannulated with
a standard sphincterotome. The initial cholangiogram showed smooth CBD/CHD compression
and a small stone within ([Fig. 1]). After a small biliary sphincterotomy, the biliary stone was extracted using a
balloon. A sudden spurt of torrential bleeding came from the papilla, suggesting a
rupture of intraductal varices ([Video 1]). A 6-cm biliary fully covered self-expandable metal stent (SEMS) (Boston Scientific,
Natick, Massachusetts, USA) was immediately inserted, as described for bleeding from
portal biliopathy in patients without situs inversus totalis ([Fig. 2]) [3]. Bleeding continued in spite of the biliary SEMS, and hence a 10-mm diameter controlled
radial expansion balloon (CRE; Boston Scientific) was inserted into the SEMS ([Video 1]). The balloon was kept inflated for 2 minutes at the partially expanded upper half
of SEMS (where the likely choledochal varices were located based on ERCP imaging).
There was no biliary bleeding at the end of balloon decompression and its removal
and for further duodenoscopic observation for next five minutes ([Video 1]).
Fig. 1 A 43-year-old man presented with obstructive jaundice. Cholangiography, with the
patient in prone position, showing smooth common bile duct/common hepatic duct compression
and a small stone (*) within.
Torrential bleeding coming from the papilla, after a small biliary sphincterotomy
and stone extraction in a patient with situs inversus totalis, a thrombosed portal
vein with cavernoma, and common bile duct/common hepatic duct obstruction. A biliary
fully covered self-expandable metal stent was placed and occluded with a controlled
radial expansion balloon to stop the bleed.
Fig. 2 A biliary fully covered self-expandable metal stent was placed in the common bile
duct to stop the bleeding.
However 2 days after the procedure, the patient developed fever (38 °C) with a rise
in bilirubin. A repeat ERCP showed biliary obstruction due to adherent clot ([Fig. 3 a]) and a 7-Fr 10-cm double-pigtail stent was placed within the SEMS ([Fig. 3 b]). After 3 months the SEMS along with the plastic stent was removed. No oozing occurred
after SEMS removal. Another 7-Fr 10-cm double-pigtail stent was placed because of
persistent biliary stricture ([Fig. 4]). No adverse events were reported at the 3-month follow-up after SEMS removal.
Fig. 3 a Cholangiogram 2 days after bleeding, showing filling defects (clots) occluding the
biliary ducts and the self-expandable metal stent. b A plastic stent was then inserted into the metal stent.
Fig. 4 a Cholangiogram 3 months later showing persistent common hepatic duct compression after
removal of metal and plastic stents. b Another plastic stent was therefore placed.
Endoscopy_UCTN_Code_CPL_1AK_2AF
