Neuropediatrics 2017; 48(01): 045-048
DOI: 10.1055/s-0036-1584939
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Effectiveness of Electroconvulsive Therapy for Refractory Status Epilepticus in Febrile Infection–Related Epilepsy Syndrome

Alicia Mirás Veiga
1   Department of Pediatric Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain
,
David Conejo Moreno
2   Department of Pediatric Neurology, Hospital Universitario de Burgos, Burgos, Spain
,
Ana Isabel Gómez Menéndez
3   Department of Neurophysiology, Hospital Universitario de Burgos, Burgos, Spain
,
Ignacio Muñoz Siscart
4   Department of Psychiatry, Hospital Universitario de Burgos, Burgos, Spain
,
Marta Del Olmo Fernández
5   Department of Pediatrics, Hospital Río Carrión, Palencia, Spain
,
Esteban Gómez Sánchez
1   Department of Pediatric Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain
,
María García González
1   Department of Pediatric Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain
,
Fernando Gómez Sáez
1   Department of Pediatric Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain
› Author Affiliations
Further Information

Publication History

31 March 2016

23 May 2016

Publication Date:
19 July 2016 (online)

Abstract

Febrile infection–related epilepsy syndrome (FIRES) is a rare condition which evolves into refractory status epilepticus (SE), with poor outcome in most cases. Conventional antiepileptic drugs fail to control SE in FIRES patients. We report the case of a previously healthy 4-year-old boy who was diagnosed with FIRES. One week after pharyngitis and high fever he started seizures, followed by refractory SE. Benzodiazepines, phenytoin, high-dose barbiturates that induce burst suppression, high doses of corticosteroids, plasmapheresis, immunoglobulins, propofol, lidocaine, ketamine, inhaled desflurane, ketogenic diet, lacosamide, and therapeutic hypothermia were tried at different times in a period of 8 weeks, but all of them were ineffective. Electroconvulsive therapy (ECT) has been used in refractory SE in children. We report a case in which ECT was successfully used for treatment of refractory SE in a pediatric patient with FIRES syndrome.

 
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