Childhood Leukaemia Clustering – Fact or Artefact?

J. F. Bithell

doi:10.1055/s-0038-1634474

Methods of Information in Medicine, Inhaltsverzeichnis

Methods Inf Med 2001; 40(02): 127-131
DOI: 10.1055/s-0038-1634474

Original Article

Schattauer GmbH

Childhood Leukaemia Clustering – Fact or Artefact?

Autor*innen

J. F. Bithell

¹University of Oxford, UK

Abstract

There is a general belief that the clustering of childhood leukaemia is a widespread phenomenon and that it provides evidence for appreciable environmental influence on the incidence of the disease. We discuss this issue critically, identifying different kinds of clustering and their possible aetiological mechanisms and examining some analyses of British data. We argue that, in some cases, analyses have been used which lead to dubious conclusions, and that, allowing for multiple testing and anecdotal reporting, the total evidence for clustering is at best weak.

Keywords

Clustering - Childhood Leukaemia - Geographical Epidemiology

Volltext

Referenzen

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