Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1959; 3(04): 658-674DOI: 10.1055/s-0038-1654421 Übersichten — Reviews — Revues générales Schattauer GmbH Factor VIII Antihemophilic Globulin[*)] Authors Author Affiliations Alfredo Pavlovsky *) 1 General Review Recommend Article Abstract Full Text PDF Download(opens in new window) References References 1 Addis T. The pathogenesis of hereditary hemophilia. J. Path. Bact 1911; 15: 427 2 Aggeler P. M, White S. G, Glendening M. B, Page E. W, Leake T. B, Bates G. Plasma thromboplastin component (PTC). Proc. Soc. exp. Biol. (N.Y.) 1952; 79: 692 3 Alexander B. The clotting defect in Hemophilia (discussion). The hemophilia and hemophilioid diseases. Ed. Brinkhous; Chapel Hill: 1957: 22 4 Alexander B, Landwehr G. Studies of hemophilia II. The Assay of the antihemophilic clot-promoting principle in normal human plasma with some observation on the relative potency of certain plasma fraction. J. clin. Invest 1948; 27: 98 4a Andino P. A, Pavlovsky A. Tratamiento de la hemofilia. Symposium sobre Factor VIII. Acad. Nac. Med. Bs. As. Agosto. 1959 5 Bendien W. M, van Creveld S. Onderzoekinger over haemophilie. Maandschr. Kindergeneesk 1936; 5: 179 6 Bergna L. J, Pavlovsky A. Método para clasificar a los hemofílicos complicados por el desarrollo de un anticoagulante. Rev. Arg. de Hemat. y Hemoterapia 1955; 2: 138 7 Bergna L. J, Pavlovsky A. Valoración del factor Villi y IX en la hemofilia A y B. Symposium sobre el Factor VIII. Acad. Nac. Med. Bs. As. Agosto. 1959 7a Bergsagel D. E, Biggs R. The Christmas Factor. Rev. Hémat 1955; 10: 354 8 Bidwell E. The purification of bovine antihaemophilic Globulin. Brit. J. Haematol 1955; 1: 35 9 Biggs R, Douglas A. S. The thromboplastin generation test. J. clinfl Path 1953; 6: 23 10 Biggs R, Douglas A. S, Macfarlane R. G, Dacie J. V, Pitney W. R, Merskey C, O’Brien J. R. Christmas disease. Brit. med. Journ 1952; 2: 1378 11 Biggs R, Douglas A. S, Macfarlane R. G. The formation of thromboplastin in human blood. J. Physiol. (Lond.) 1953; 119: 89 12 Biggs R, Eveling S, Richards G. T. The assay of Antihemophilic activity. Brit. J. Haematol 1955; 1: 1 13 Biggs R, Macfarlane R. G. Haemophilia and related conditions. A Survey of 187 cases. Brit. J. Haematol 1958; 4: 1 14 Blombäck M. Studies on antihemophilic globulin. Acta Pediatrica, vol 1958; 47 supl 114 15 Bounameaux Y. Dosage des facteurs de coagulation contenus dans l’atmosphere plasmatique de plaquettes humaines. Rev. franc. del Et. Clin. et Biol 1957; 2: 52 16 Brakman P, van Creveld S, Engelsman E, vant Laar I. A, Mochtar I. A, Vender H. A. Deterioration of AHG (Factor VIII) and Fibrinolysis. Thromb. Diath. haem 1959; 3: 1 17 Brinkhous K. M. A study of the clotting defect in hemophilia: the delayed formation of thrombin. Amer. J. med. Sci 1939; 198: 509 18 Brinkhous K. M. Hemophilia. Bull. N.Y. Acad. Med 1954; 3: 325 19 Brinkhous K. M. Hemophilia and Hemophilioid Diseases (Int Symp.) Ed. K. M. Brinkhous; Chapel Hill: 1957 20 Brinkhous K. M, Penick G. D. Some Systemic alterations in clotting factors following local tissue Injury. Internat. Congr. on Thromb. and Embol. Basel: 1954: 428 21 Castex M. R, Paviovsky A. Hemophilic Sang. 1953; 24: 573 22 Castex M. R, Pavlovsky A, Simonetti C. Contribucion al estudio de la Fisiópatogenia de la hemofilia. Medicina 1944; 5: 16 23 Cohn E. J, Gurd F. R. N, Surgenor D. M, Barnes B. A, Brown R. K, Deronaux G, Gillespie J. M, Kahurt F. W, Lever W. F, Lin C. H, Mittelman D, Mouton R. F, Schmid R, Uroma E. A system for the separation of the components of human blood: Quantitative procedures for the separation of the protein components of human plasma. J. Amer. chem. Soc 1950; 72: 465 24 Cohn E. J, Strong L. E, Hughes W. L. S, Mulferd D. L, Ashworth J. N, Melir M, Taylor A. L. Preparation and properties of serum and plasma proteins. J. Amer. chem. Soc 1946; 68: 459 25 Cramer R, Flückiger P, Gasser C, Koller F, Loeliger A, Matter M. Hemophilia B. Acta haemat. (Basel) 1953; 10: 65 26 Deutsch E. Treatment of Surgical complications in hemophilia. Hemophilia and Hemophilioid Diseases. Ed. Brinkhous; Chapel Hill: 1957: 204 27 Fisch U, Duckert F. Some aspects of Kinetics of the first stages of blood thromboplastin formation. Thromb. Diath. haem 1959; 1: 98 28 Graham J. B. Biochemical Genetics of blood coagulation. Amer. J. hum. Genet 1956; 8: 63 29 Graham J. B, Bullock W. B, Barrow E. M. Genetic control of the hemophilioid states. Relat. VII Cong. Soc. Int. Hemat. Rome, Sept. 1958 29a Graham J. B, Barrow E. M. The pathogenesis of Hemophilia: An experimental analysis of the anticephalin hypothesis in hemophilic dogs. J. exp. Med 1957; 106: 273 30 Gross J. D, Hartmann R. C, Graham J. B, Bruce Taylor C. Splenectomy in Hemophilia. Bull. Johns Hopk. Hosp 1957; 100: 223 31 Hecht E. El problema de la hemofilia. Triangulo 1955; 2: 99 32 Hecht E. Sphingosine discovered as physiological inhibitor of blood clotting. Sixth Annual Symposium on Blood. Wayne State Univers. Detroit. 1957 33 Hougie C. The rol of factor V in the formation of blood thromboplastin. J. Lab. clin. Med 1957; 50: 61 34 Jacques L. B, Fisher L. M, Ashwin J. Platelet Serotonin as a factor in hemostasis. Int. Cong. on blood Transfusion. Roma, Sept. 1958 35 Jorpes E, Nilsson I. M, Blombäck M, Blombäck B. Correction with human plasma Fraction I—0 in Willebrands Disease. VII Congresso della Societá Inter-nazionale di Ematologia. Roma, Sept. 1958 36 Kekwick R. A, Mackay M. E. The separation of protein fractions from human plasma with ether. Spec. Rep. Serv. Med. Res. Coun. London: 286 1954 37 Kekwick R. A, Wolf P. A concentrate of Human antihaemophilic factor its use in six cases of haemophilia. Lancet 1957; 1: 647 37a Koller F, Krusse G, Lucksinger P. Über eine besondere Form hämor-rhagischer Diathese. Schweiz. med. Wschr 1950; 80: 41 38 Langdell R. D, Wagner R. H, Brinkhous K. M. Estimation of antihemophilic Activity by the Partial Thromboplastin Time Technic. The Coagulation of Blood, Ed. L. M. Tocantins; N. Y: 1955 39 Langdell R. D, Wagner R. H, Brinkhous K. M. Antihemophilic factor (AHF) levels following transfusion of blood plasma and plasma fractions. Proc. Soc. exp. Biol. (N. Y.) 1955; 88: 212 40 Lorand L, Laki K. A simple method for purifying an activator of prothrombin antihemophilic factor. Biochem. Biophys. Acta 1954; 13: 448 41 Lowenburg H, Rubenstone A. J. Hemophilia, experimental data bearing on the effect of glycerinized extracts of visceral hemophilic tissue on the coagulation time of blood. J. Amer. med. Ass 1918; 71: 1196 42 Macfarlane R. G, Biggs R, Bidwell E. Bovine antihemophilic globulin in the treatment of haemophilia. Lancet 1954; 1: 1313 43 Manteuffel Z. Bemerkungen zur Blutstillung bei Hämophilie. Dtsch. med. Wschr 1893; 19: 665 44 Margolis J. Plasma pain-producing substance and blood clotting. Nature (Lond.) 1957; b 180: 1464 45 Martinez Canaveri A, Pavlovsky A. Participación del Factor VIII en el proceso de la coagulatión. Symposium sobre el Factor VIII. Acad. Nac. Med. Bs. As. Agosto. 1959 46 Minot G. R, Davidson C. S, Lewis J. H, Tagnon H. J, Taylor F. H. L. The coagulation defect in Hemophilia: The effect in hemophilia of the parenteral administration of a fraction of the plasma globulins rich in fibrinogen. J. clin. Invest 1945; 24: 705 47 Nilsson I. M, Blombäck M, Jorpes E, Blombäck B, Johansson S. v. Willebrand’s Disease and its correction with Human plasma Fraction 1–0. Acta med. scand. vol. CLIX, Fasc. 1957: III 48 Owren P. A. The present state of the converting and accelerating factors in Prothrombin conversion. Internat. Conf. on Thromb. and Embol. Basel: 1954: 65 49 Patek A. J, Stetson R. P. The abnormal coagulation of the blood and its relation to the blood platelets. J. clin. Invest 1936; 15: 5 50 Patek A. J, Taylor F. H. L. Some properties of a substance obtained from human plasma effective in accelerating the coagulation of hemophilic blood. J. clin. Invest 1937; 16: 113 51 Pavlovsky A. Contribution to the Pathogenesis of Hemophilia. Blood 1947; 2: 185 52 Pavlovsky A. Present concepts of Hemophilia. Blood 1954; 9: 291 53 Pavlovsky A. Hemophilia. Pren. méd. argent 1958; 65: 2365 54 Pavlovsky A. Symposium on Hemophilia. VII Cong. Internat. Haemat. Roma, Sept. 1958 55 Pavlovsky A, Bergna L, Martinez Canaveri A. Thromboplastin in Hemophilia. Sang 1955; 26: 162 56 Pavlovsky A, Martinez Canaveri A, Andino Pavlovsky A. Emoterapia nella hemofilia. Relato al VII congreso de la Sociedad Internacional de Transfusión de sangre. Roma, Sept. 1958 57 Pavlovsky A, Martinez Canaveri A, Simonetti C, Arini E. Hemophilia. Comparative study of varieties of A and B. Report VI Congr. Int. Soc. Hem. Boston: 1956 58 Pavlovsky A, Mittelman D. G. de, Castellanos H. Interacción de plasma de distintos hemofilicos. Reunión Anual Ins. de Inv. Fis. aplic. a la Pat. Hum. Acad. Nac. Med. Bs. As. Dec. 1950 59 Pavlovsky A, Pavlovsky M. C. de. Female Haemophilia. Symposium on Hemophilia. VII congreso de la Soc. Int. de Hem. Roma, Sept. 1958 60 Pavlovsky A, Simonetti C. Determinación del poder coagulante de la fracción globulina extraída de plasmas hemofilicos. An. del Inst. Inv. Acad. Nac. Med 1944; 6: 341 61 Pavlovsky A, Simonetti C, Andino A. Hemofilia. Considerazioni sulla sua coagulazione. Relato VII Cong. de la Soc. Int. de Hemat. Roma: 1958 62 Penick G. D, Brinkhous K. M. Relative stability of plasma antihemophilic factor (AHF) under different conditions of storage. Am. J. med. Sci 1956; 232: 434 63 Pitney W. R. The assay of antikaemophilic globulin (AHG) in plasma. Brit. J. Haematol 1956; II: 3 64 Pool G. J, Robinson J. Assay of plasma antihemophilic globulin (AHG). Brit. J. Haematol 1959; 5: 17 65 Pool J. G, Spaet T. H. Ethionine induced depresion of plasma antihemophilic globulin in the rat. Proc. Soc. exp. Biol. (N. Y.) 1954; 87: 54 66 Quick A. J. The Hemorrhagic Diseases and the Physiology of Hemostasis. Charles C. Thomas; Springfield, Illinois: 1942 67 Quick A. J. Hemorrhagic Diseases. Lea and Febriger; Philadelphia: 1957 68 Quick A. J, Daniels E. R, Hussey C. V. Acquired antithromboplastino-genemia (Hemophilia-like disease) with special reference to its diagnosis. J. Lab. clin. Med 1954; 44: 94 69 Quick A. J, Stanley-Brown M, Bancroft F. W. A study of the coagulation defect in hemophilia and in jaundice. Amer. J. med. Sci 1935; 190: 501 70 Ratnoff O. D, Margolius A. International Symposium on Hemophilia and Hemophilioid Diseases. Ed. Brinkhous; Chapel Hill: 1957: p. 125 71 Schulman I. Management of Hemorrhage in hemophilia. Discussion. Hemophilia and Hemophilioid Diseases. Ed. K. M. Brinkhous; Chapel Hill: 1957: 215 72 Schulman I, Smith C. H. Hemorrhagic disease in an infant due to deficiency of a previously undescribed clotting factor. Blood 1952; 7: 794 73 Seegers W. H. Nature of the blood coagulation mechanisms. I. Inter. Conf. on Thromb. and Embol. 1954. Basel: 31 74 Seegers W. H, Landaburu R. H, Fenichel L. Isolation of platelet cofactor I from plasma and some properties of the preparation. Amer. J. Physiol 1957; 190: 1 75 Shinowara G. Y. Studies on the purification of Thromboplastic Plasma component (antihemophilic substance) in human blood. Amer. J. med. Sci 1957; 233: 5 76 Simonetti C, Casillas G, Pavlovsky A. Valoración de los metodos para purificar el factor VIII. Symposium sobre factor VIII. Acad. Nac. Med. Bs. As Agosto. 1959 77 Sjölin K. E. Classical Haemophilia (AHF deficiency) and Christmas Factor (PTC) deficiency as Simultaneous defects. Acta med. scand 1957; 159: 7 78 Sjölin K. E. A group of AHF deficient patients, corrected by adsorbed serum. Trans of the 6th. Congr. of the Europ. Soc. of Haemat. 1957: 164 79 Soulier J. P. Un nouvel adsorbant des facteurs de coagulation. La Bentonite. Rev. Hémat 1959; 14: 26 79a Soulier J. P. Standardization of So-called Antihemophilic Fractions. Hemophilia and Hemophilioid diseases. Ed. Brinkhous; Chapel Hill: 1957: 18 80 Soulier J. P, Gobbi F, et Larrieu M. J. Separation du Fibrinogene et du facteur antihemophilique A. Rev. Hématol 1957; 12: 481 81 Soulier J. P, Larrieu M. J. Nouvelle méthode de diagnostic de l’hemophilie: dosage des facteurs antihemophiliques A et B. Sang 1953; 24: 205 82 Soulier J. P, Wartelle O, Menachee D. Hageman Trait and PTA deficiency; the rol of contact of blood with glass. Brit. J. Haematol 1959; 5: 121 83 Spaet T. H, Aggeler P. M, Richards M. O. Prophylactic management of Hemophilia and PTC deficiency. Hemophilia and Hemophilioid diseases. Ed. Brink-hous; Chapel Hill: 1957: 11 84 Spaet T. H, Kinsell B. G. Properties of bovine antihemophilic factor. Proc. Soc. exp. Biol. (N. Y.) 1953; 84: 314 85 Taylor F. H. L, Davidson C. S, Tagnon H. J, Adams M. A, Mac-Donald A. H, Minot G. R. Studies in blood coagulation: the coagulation properties of certain globulin fractions of normal human plasma “in vitro”. J. clin. Invest 1945; 24: 698 85a Tocantins L. M, Caroll R. T, Holburn R. H. The clot accelerating effect of dilution on blood and plasma; relation to the mechanism of coagulation of normal and hemophilic blood. Blood 1951; 6: 720 86 Verstraete M. De Vorming van Plasma Thromboplastine — Arscia Uitgaven Stoofsträat 60. Brussel: 1955 87 Verstraete M, Vandenbroucke J. Combined antihemophilic Globulin and Christmas factor deficiency in haemophilia. Brit. Med. J 1955; 11: 1533 88 Wagner R. H, Thelin Murray G. Antihemophilic Factor: Current Status of Purification Chemical and Physical characterization. Hemophilia and Hemophilioid Diseases. Ed; Brinkhous Chapel Hill: 1957: 3 89 Winterstein A, Marbet R, Strassle R. Isolation, Stability and assay of Antihemophilic globulin. Hemophilia and Hemophilioid Diseases. Ed; Brinkhous, Chapel Hill: 1957: 11 90 Wolf P. Studies of Temperature and pH stability of Human antihaemophilic Factor (AHF) in plasma and in a concentrate. Brit. J. Haematol 1959; 5: 169
