Lymphoma is the second most common type of gastric cancer, especially MALT and diffuse
large B cells lymphomas. A very rare but highly aggressive lymphoma is Burkitt lymphoma.
Man, 72 years with epigastralgia, melena and anemia. In urgent gastroscopy, a large
excavated ulcer is observed on the underside of the antrum (1-3). Biopsies show CD20+/bcl-6+/CD10+
lymphoid cells on the lamina propria, over-expression of c-myc and Ki67>90%, compatible
with Burkitt lymphoma. PET/CT (4) shows large gastric hypermetabolic mass, with multiple
intra-abdominal nodules. Chemotherapy (R-DA-EPOCH scheme) achieves complete metabolic
remission in PET/CT at the end of treatment (5).