Prevalence of Barrett’s Esophagus in a South European Country:A Multicentre, Cross-Sectional Study

I Marques de Sá; C Leal; J Silva; D Falcão; C Felix; C Nascimento; P Boal Carvalho; H Vasconcelos; I Pedroto; C Chagas; M Cravo; J Cotter; P Sharma; M Dinis-Ribeiro

doi:10.1055/s-0041-1724336

Endoscopy, Table of Contents

Endoscopy 2021; 53(S 01): S32-S33
DOI: 10.1055/s-0041-1724336

Abstracts | ESGE Days

ESGE Days 2021 Oral presentations

Thursday, 25 March 2021 18:00 – 18:45 Barrett’s and beyond Room 6

Prevalence of Barrett’s Esophagus in a South European Country:A Multicentre, Cross-Sectional Study

Authors

I Marques de Sá

¹Portuguese Oncology Institute of Porto, Gastroenterology, Porto, Portugal
C Leal

²Centro Hospitalar de Leiria, Gastroenterology, Leiria, Portugal
J Silva

³Centro Hospitalar do Porto, Gastroenterology, Porto, Portugal
D Falcão

³Centro Hospitalar do Porto, Gastroenterology, Porto, Portugal
C Felix

⁴Centro Hospitalar Lisboa Ocidental, Gastroenterology, Lisboa, Portugal
C Nascimento

⁵Hospital Beatriz Ângelo, Gastroenterology, Lisboa, Portugal
P Boal Carvalho

⁶Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal
H Vasconcelos

²Centro Hospitalar de Leiria, Gastroenterology, Leiria, Portugal
I Pedroto

³Centro Hospitalar do Porto, Gastroenterology, Porto, Portugal
C Chagas

⁴Centro Hospitalar Lisboa Ocidental, Gastroenterology, Lisboa, Portugal
M Cravo

⁵Hospital Beatriz Ângelo, Gastroenterology, Lisboa, Portugal
J Cotter

⁶Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal
P Sharma

⁷University of Kansas School of Medicine Center, Kansas City, United States

⁸Veterans Affairs Medical Center, Gastroenterology, Kansas city, United States
M Dinis-Ribeiro

¹Portuguese Oncology Institute of Porto, Gastroenterology, Porto, Portugal

⁹Faculty of Medicine, University of Porto, CINTESIS/Department of Biostatistics and Medical Informatics, Porto, Portugal

Abstract

Full Text

Aims The identification of Barrett’s esophagus (BE) with detection and treatment of dysplasia is essential to prevent adenocarcinoma. Therefore, the determination of BE prevalence is important to define screening and subsequent surveillance strategies. However, precise estimates on BE prevalence from several European countries are lacking. We aimed to determine BE prevalence in Portugal.

Methods We conducted a cross-sectional, multicentre study from November 2019 to February 2020. BE was defined as columnar extent in the distal esophagus ≥1cm with intestinal metaplasia on biopsies. The quality of endoscopy was evaluated according to published guidelines and blinded to centre and endoscopist.

Results 1550 individuals, 51 % male and mean age of 62 (+/-15) years undergoing upper endoscopy were included in the study. The overall prevalence of BE was 1.29 % (95 %CI=0.73-1.85); significantly higher in men [2.05 % (1.06-3.04) vs women 0.53 % (0,01-1.04)]. Of the 20 BE patients, 8 were newly diagnosed and 12 were under surveillance. The median extent was C3 (min0; max16) M4.5 (min2; max16). One patient each had EAC (0.06 %) and HGD (0.06 %). There was no difference in BE prevalence between different regions, endoscopic centres, use of sedation or level of experience of endoscopists. Considering all endoscopy reports, 93 % used standardized terminology, 23 % accurate photodocumentation and 69 % photodocumented the esophagogastric junction (EGJ). In addition, 80 % used Prague classification, 55 % Seattle protocol, 60 % distance to the squamocolumnar junction, 75 % to the EGJ and 40 % to the hiatal pinch. When considering only reports with EGJ photodocumentation or Prague classification, the prevalence was 1.78 % (CI_95 %:0.91;2.64) or 1.03 % (CI_95 %:0.53;1.53), respectively.

Conclusions In a cross-sectional, multicentre study, we report for the first time BE prevalence in Portugal and report a low overall prevalence of 1.3 % in an unselected population undergoing endoscopy. Future studies need to determine progression rates and how to improve quality metrics for upper endoscopy.

Citation: Marques de Sá I, Leal C, Silva J et al. OP77 PREVALENCE OF BARRETT’S ESOPHAGUS IN A SOUTH EUROPEAN COUNTRY:A MULTICENTRE, CROSS-SECTIONAL STUDY. Endoscopy 2021; 53: S32.