Endoscopy 2022; 54(S 01): S252
DOI: 10.1055/s-0042-1745294
Abstracts | ESGE Days 2022
ESGE Days 2022 Digital poster exhibition

EUS-FNA/FNB AND ERCP IN THE DIAGNOSTIC WORK-UP OF BILIARY STENOSIS: A RETROSPECTIVE STUDY

Authors

  • F. Gadaleta

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • E. Troncone

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • L. Montesano

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • M. Mossa

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • E. Grasso

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • G. Monteleone

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy

  • G. Del Vecchio Blanco

    1   Department of Systems Medicine, Gastroenterology Unit, University of Rome Tor Vergata, Rome, Italy
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    Aims Defining the etiology of biliary stenosis is challenging, and endoscopic tissue sampling often shows a low diagnostic yield. We evaluated the diagnostic yield of endoscopic ultrasound (EUS) fine-needle aspiration/biopsy (FNA/FNB) and endoscopic retrograde cholangiopancreatography (ERCP) brushing/biopsy in biliary stenosis

    Methods We retrospectively reviewed EUS-FNA/FNB and ERCP procedures performed in patients with biliary stenosis from November 2015 to September 2021 at the Policlinico Tor Vergata, Rome, Italy. Final diagnosis was obtained from surgical specimens or clinical/radiological follow-up

    Results Fifty-two patients (31 males; median age 73, range 49-94) underwent 75 endoscopic procedures: 46 ERCP with brushing/biopsy, 23 EUS-FNB, 6 EUS-FNA (15 patients underwent both ERCP and EUS sampling; 4 patients underwent 2 ERCP, 1 patient 3 ERCP and 2 patients 2 EUS-FNA/FNB after negative histology/cytology). Malignancy was diagnosed in 28/52 (53.8%) patients. The sensitivity, specificity, and diagnostic accuracy of ERCP brushing/biopsies were 66.7%, 100%, and 84.8% respectively, and those of EUS- FNA/FNB were 71.4%, 100%, and 80%, respectively. In the cases in which both EUS-FNA/FNB and ERCP were performed, sensitivity, specificity and diagnostic accuracy were 81.8%, 100% and 86.6%.

    Overall, sensitivity, specificity and diagnostic accuracy of endoscopic sampling with EUS-FNA/FNB or ERCP in our population were 80.6%, 100% and 90%.

    Conclusions Endoscopic tissue sampling with EUS-FNA/FNB and/or ERCP brushing/biopsies showed high diagnostic yield in patients with biliary stenosis. In selected cases, performing both procedures increases sensitivity and diagnostic accuracy compared to individual procedures


     

    Publication History

    Article published online:
    14 April 2022

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