Keywords 3D additive manufacturing - adhesion - CAD/CAM - maxillary lateral incisor agenesis
- monolithic ceramics - shear bond strength - surface energy
Introduction
Maxillary lateral incisor agenesis (MLIA) is a prevalent nonsyndromic congenital tooth
agenesis, often bilateral,[1 ]
[2 ] and associated with reduced maxillary sagittal growth and altered relative lower
incisor position,[3 ] making functional postorthodontic stabilization pertinent. Its challenging treatment
has valuable aesthetic options, including orthodontic space opening followed by lateral
incisor prosthetic replacement or space closure with canine mesialization complemented
by tooth remodeling.[4 ]
[5 ] Single-retainer resin-bonded bridges (RBBs) are aesthetic, minimally invasive restorative,
and reversible options for interim or definitive rehabilitation in cases of space-opening
procedures,[4 ]
[5 ] mainly in clinical situations with ongoing maxillofacial growth due to periodontal
and aesthetic factors.[6 ]
[7 ]
[8 ]
Computer-aided design and computer-aided manufacturing (CAD/CAM) materials are versatile
for aesthetic restorations, but clinical evidence-based data concerning their success
and durability still need to be explored.[9 ]
[10 ] Available for digital workflow, these industrial materials evolve faster than the
data returned from high-quality clinical trials,[11 ] leading clinicians and dental prosthetics to doubts about optimizing the available
options.[12 ] Furthermore, in vitro studies usually integrate equipment unavailable in clinical
settings, and only some experimental protocols can be transposed directly from the
laboratory to the clinical context,[11 ] making pertinent experimental designs that simulate clinical situations and settings
and uses standardized base adherends to avoid the heterogeneity of the natural teeth.
CAD/CAM monolithic ceramics are mainly polycrystalline, glass-matrix, indirect composites,
and hybrid ceramics.[13 ]
[14 ] The polycrystalline ceramic Vita YZ HT (Y-ZPT) (VITA Zahnfabrik, Bad Säckingen,
Germany) is a 5 mol% yttria-stabilized zirconia and a standard for new generations
by its physical and mechanical characteristics (opaque white appearance and high flexural
strength/1,200–1,500 MPa).[15 ]
[16 ]
Combining a low flexural modulus with a high flexural strength (150–160 MPa), the
hybrid ceramic Vita Enamic (ENA; VITA Zahnfabrik) is a polymer-infiltrated ceramic
network[13 ] capable of elastic deformation before failure, with a mechanical behavior similar
to that of a human tooth.[17 ] Despite the low stiffness,[18 ] it is quite stable under extreme acid exposure, and cyclic loading does not affect
its properties.[19 ] Its unique polymer-based microstructure is essential for the micromechanical bond
and the performance of the adhesive interface[20 ]
[21 ] due to a decreased crack propagation.[22 ] High translucency, fluorescence, and opalescence are the main characteristics of
Vita Suprinity (SUP; VITA Zahnfabrik), according to the manufacturer. This homogeneous
fine-grained glass-ceramic enriched with zirconia has a consistently high load capacity
(flexural strength in crystallized state, 420 MPa). Delivered precrystallized, it
is an interesting material for anterior RBBs because of its aesthetics, biocompatibility,
mechanical properties, and more straightforward adhesive protocol.[13 ]
[14 ]
[23 ] Clinical data remain scarce, often controversial, and limited to short-term observational
periods.[24 ]
[25 ]
Medical ABS (acrylonitrile butadiene styrene; Smart Materials 3D, Jaén, Spain; ISO
10993–1) is a lightweight bisphenol A (BPA) free thermoplastic polymer that attains
tensile strengths ranging from 15 to 38 MPa with an elastic modulus of 1,300 to 1,800
MPa. Produced via fused deposition, its mechanical behavior depends on processing
temperatures, printing parameters, proportions of monomers in the ABS structure, and
force orientation during testing.[26 ]
The quality of an adhesive joint is determined by the bond quality at different interfaces
and the adhesive strength of the restorative materials, as in the case of RBBs. The
interfaces between the dental tissue and the adhesive cement and the connection between
the cement and the surface of the restorative material play essential roles.[27 ] In this process, adhesion and cohesion[23 ]
[28 ] are involved, with the first between the substrates and the second within each substrate.
Characterization of the interface before adhesion, during function, and after failure
is helpful in adhesive joint research and remains a significant challenge[28 ] because a specific adhesive protocol is required for each paired material to obtain
the highest bond strength.[11 ]
[29 ]
Advances in adhesive dentistry and technology expanded the use of RBBs with alternative
preparation designs and materials.[30 ] To best predict the future clinical performance of CAD/CAM materials to fabricate
RBBs, similar designs and fabrication procedures following real dental laboratory
and clinical procedures should be chosen.[31 ] Meanwhile, it is accepted that the adhesive strength of zirconia depends on particle
abrasion and primers or adhesives containing 10-methacryloxydecyl dihydrogen phosphate
(MDP).[32 ]
[33 ]
This study evaluated single-retainer RBBs manufactured similarly to those for clinical
application in MLIA. Three CAD/CAM monolithic ceramics and one additive-manufactured
CAD/CAM material adhered to an artificial tooth with dual-cured cement were assessed
for shear bond strength (SBS) and fracture mode. The null hypothesis was that no differences
would be observed between the SBS of the tested materials in the tested RBB model.
Materials and Methods
The materials used in this study are listed in [Table 1 ]. Polycrystalline zirconia (Y-ZPT) was used as control material. Based on previous
research,[21 ] a photoinitiated dual-cured adhesive cement, RelyX Ultimate (RU; 3M ESPE, Seefeld,
Germany), used in a three-step adhesive strategy, was used to adhere the experimental
RBBs to an artificial tooth.
Table 1
General description of materials used in this study, their compositions, and manufacturers
Material
Name
Code
Composition
Manufacturer
CAD-CAM monolithic ceramics
Vita Enamic
ENA
86% feldspar ceramic: SiO2 58–63%, Al2 O3 20–23%, Na2 O9 –11%, K2 O4 –6% by weight, 14% polymer by weight: TEGDMA, UDMA
VITA Zahnfabrik, Bad Säckingen, Germany
Vita Suprinity
SUP
Zirconium oxide 8–12%, silicon dioxide 56–64%, lithium oxide 15–21%, various > 10%
by weight
VITA Zahnfabrik
Vita 5Y-TPZ Color
Y-ZPT
Zirconia reinforced with 5% yttria
VITA Zahnfabrik
CAD-CAM 3D-printed material
Medical ABS
ABS
Acrylonitrile butadiene styrene
Smart Materials 3D, Jaén, Spain
Resin-matrix composite cement
RelyX Ultimate
RU
MDP phosphate monomer, dimethacrylate resins, HEMA, Vitrebond copolymer filler, ethanol,
water, initiators, silane
3M Oral Care, St. Paul, MN, United States
Etching agent
Porcelain Etch Gel
PEG
Hydrofluoric acid 9.6%
Pulpdent, Watertown, MA, United States
Ceramic primer
Monobond Plus
MB
50–100% ethanol, disulfide methacrylate, ≤2.5% phosphoric acid dimethacrylate, ≤2.5%
3-trimethoxysilylpropyl methacrylate
Ivoclar Vivadent AG, Schaan, Liechtenstein
Adhesive system
Scotchbond Universal adhesive
SB-U
MDP, Bis-GMA, phosphate monomer, dimethacrylate resins, HEMA, methacrylate-modified
polyalkenoic acid copolymer, filler, ethanol, water, initiators, silane-treated silica
3M Oral Care
Hydrophobic resin
Heliobond
HEL
HEMA, Bis-GMA, UDMA, initiators (camphorquinone and benzoyl peroxide), fillers (silica,
glass particles), and solvents (ethanol and acetone)
Ivoclar Vivadent AG
Artificial teeth
Frasaco tooth
FRA
Melamine-based composition
Frasaco GmbH, Tettnang, Germany
Abbreviations: HEMA, hydroxyethylmethacrylate, MDP, 10-methacryloyloxydecyl dihydrogen
phosphate; TEGDMA, UDMA, urethane dimethacrylate; triethylene glycol dimethacrylate.
Acquisition and Processing of Digital Images
Digital images of a Frasaco A3 Adult Typodont (Frasaco GmbH, Tettnang, Germany) were
acquired using a Medit i700 intraoral scanner (MEDIT Corp., Seoul, Republic of Korea)
and processed using the software Medit Link v3.0.6 Build 286, and Medit Scan for Clinics
v1.9.6 Revision 268 (MEDIT Corp.; [Fig. 1 ]).
Fig. 1 Images acquired using an intraoral scanner. (A ) Reference data from both maxillaries in frontal view, (B ) occlusion data, (C ) reference maxilla in occlusal view, (D ) maxilla simulating a lateral incisor agenesis, (E ) the same in detail, (F ) a view from palatal, and (G ) maxilla simulating a lateral incisor agenesis in occlusal view.
[Fig. 2 ] shows the main steps of the data processing of the digital workflow (3Shape CAD/CAM
software, Copenhagen, Denmark), focusing on material resistance and occlusal contacts.
The connector area was set at 6.6 mm2 , limited by the vestibular, incisal, and gingival parameters. The minimum thickness
for the retainer wing was 0.5 mm. This procedure was repeated according to the manufacturer's
instructions for each monolithic CAD/CAM ceramic.
Fig. 2 Stereolithography (STL) images uploaded to 3Shape software. (A,B ) Reference data from both maxillaries in frontal view (with and without the lateral
incisor) for the calibration of the occlusal plane. (C,D,d,δ ) Details of the planned resin-bonded bridge (RBB). (F,G,g,λ ) Details of the planned RBB to be milled from an ENA block. (H ) The digital case mounted in the digital articulator.
Single-Retainer Bridge Production
After the digital design, monolithic RBBs were fabricated using a CAD-CAM inLab milling
machine (Dentsply/Sirona, Charlotte, NC, United States), following the manufacturer's
laboratory procedures. By fused deposition, Medical ABS RBBs were constructed using
a Pro2 3D printer (Raise3D, Irvine, CA, United States).
Cementation of the Resin-Bonded Bridges
Frasaco right central incisors (Frasaco GmbH) were used as adherends. As in a clinical
context, the superficial glossy surface was removed using a coarse diamond bur simulating
the intraoral removal of the aprismatic or fluoridated enamel, followed by surface
conditioning for 60 seconds with 5% hydrofluoric acid. The prepared teeth were shuffled
to ensure randomization and operator blinding. A 20-second oil-free air/water spray
removed the produced debris. [Table 2 ] lists the adhesive protocols used for each type of material. RelyX Ultimate cement
was applied using a three-step adhesive strategy and allowed to self-cure for 7 minutes
after 5 seconds of photoinitiation (Elipar S10 curing unit, 1,200 mW/cm2 ; 3M ESPE) through the buccal and palatal sides of the Frasaco tooth. All the steps
were performed by the same restorative dentist (single operator) with greater than
30 years of clinical experience.
Table 2
Materials used for adherends' surface treatment and adhesion
Cement
Substrate
Surface treatment (Frasaco tooth)
Surface treatment (RBB)
Adhesive system
RelyX Ultimate
ABS
5% hydrofluoric acid
Heliobond
Scotchbond Universal
Enamic
5% hydrofluoric acid
9.6% hydrofluoric acid 60 s
Suprinity
5% hydrofluoric acid
9.6% hydrofluoric acid 20 s
Y-ZPT
5% hydrofluoric acid
Al2 O3 sandblasting
Abbreviations: ABS, acrylonitrile butadiene styrene; RBB, resin-bonded bridge.
Mechanical Testing of Resin-Bonded Bridges
The four groups of RBB specimens (Y-ZPT, SUP, ENA, and ABS) were mechanically assessed
under load displacement of 0.2 mm/min (Instron–Universal tensile machine). [Fig. 3A ] and [B ] shows details of the shear-bond test settings. Load-displacement curves were recorded
during the mechanical test. The maximum load in the test was used to identify the
experimental RBB that supported the highest shear stress, and the highest shear stress
supported by the adherend before cohesive failure.
Fig. 3 (A ) Scheme of the components designed for testing (1, block stabilizer; 2, base adherend
incorporated in acrylic resin block; 3, load cell and piston; 4, stationary base;
5, resin-bonded bridge [RBB] to be tested). (B ) Photograph of the shear bonding test with block stabilized on the stationary base
and RBB tooth positioned for shear bond strength (SBS) with the piston positioned
2 mm away from the incisal border.
Data Analysis
The load to fracture (N) and mean shear stress (MPa) with standard deviations (SD)
registered for each group were compared using boxplot graphics. One-way analysis of
variance (ANOVA) followed by the Tukey–Kramer post hoc test was used to compare the
differences (α = 0.05). A meta-analysis focusing on CAD/CAM materials evaluated the magnitude of
the difference between groups based on differences in means and effect sizes (α = 0.05; 95% confidence interval [CI]; Z -value = 1.96) using a software program (Stata v18.0; StataCorp, College Station,
TX, United States). The failure mode was determined by microscopic observation and
correlated with the maximum load to fracture of the specimen.
Results
The mechanical behavior, SBS, and failure mode results are shown in [Fig. 4A ] and [Table 3 ]. Despite having a lower performance, the ABS was more consistent, and observing
the curve during loading suggested a marked plastic deformation before failure. Box
plots in [Fig. 4B ] allows rapid visualization of the different mechanical performance between materials.
The compared mean ± standard deviation values for the adhesive strength were ENA (24.24 ± 9.05
MPa) < ABS (24.01 ± 1.94 MPa) < SUP (29.17 ± 4.78 MPa) < Y-ZPT (37.43 ± 12.20 MPa).
Fig. 4 (A ) Specimens behavior under load, from the control group (Y-ZPT), Suprinity, Enamic,
and ABS groups. (B ) Box plots of shear strength (MPa) of resin-bonded bridges (RBBs) by type of material.
(C ) Forest plot summarizing the effect size of the Computer-aided design and computer-aided
manufacturing (CAD/CAM) materials and (D ) comparative procedure between groups after analysis of variance (ANOVA).
Table 3
Compression strength and mode of failure by group and sample
Groups
Compression strength
Mode of failure
N
MPa
Sample
AD
C_A
C_RBB
RelyX Ultimate
Medical ABS
158.45
24.01
1
x
x
Medical ABS
176.22
26.70
2
x
x
Medical ABS
140.36
21.27
3
x
x
Medical ABS
158.28
23.98
4
x
x
Medical ABS
162.60
24.64
5
x
x
Failure load
Shear strength
Mean (N)
SD (N)
Mean (MPa)
SD (MPa)
159.18
12.82
24.12
1.94
AD
C_A
C_RBB
Vita Enamic
170.52
25.84
1
x
x
Vita Enamic
61.09
9.26
2
x
x
Vita Enamic
158.45
24.01
3
x
x
Vita Enamic
191.42
29.00
4
x
Vita Enamic
218.30
33.08
5
x
x
Failure load
Shear Strength
Mean (N)
SD (N)
Mean (MPa)
SD (MPa)
159.96
59.75
24.24
9.05
AD
C_A
C_RBB
Vita Suprinity
171.75
26.02
1
x
x
Vita Suprinity
172.16
26.08
2
x
x
Vita Suprinity
221.43
33.55
3
x
x
Vita Suprinity
165.31
25.05
4
x
x
Vita Suprinity
232.03
35.15
5
x
x
Failure load
Shear strength
Mean (N)
SD (N)
Mean (MPa)
SD (MPa)
192.54
31.56
29.17
4.78
AD
C_A
C_RBB
Vita Y-ZPT
271.40
41.12
1
x
x
Vita Y-ZPT
375.01
56.82
2
x
x
Vita Y-ZPT
224.90
34.08
3
FTF
FTF
Vita Y-ZPT
180.4
27.33
4
x
Vita Y-ZPT
183.49
27.80
5
x
Failure load
Shear Strength
Mean (N)
SD (N)
Mean (MPa)
SD (MPa)
247.04
80.53
37.43
12.20
Abbreviations: AD, adhesive failure; C_A, adherend cohesive failure; C_RBB, bridge
cohesive failure; FTF, Frasaco tooth fracture; SD, standard deviation.
[Fig. 4C ] shows that the mechanical performance of Y-ZPT was significantly better than that
of the others (p < 0.001). [Fig. 4D ] shows the results of the compared differences (α = 0.05), highlighting the superior shear strength of Y-ZPT, particularly with ENA
and ABS. The failure modes were mainly adhesive for Y-ZPT, cohesive in the RBB for
SUP and ENA, and cohesive with plastic deformation of the RBB for ABS ([Figs. 5 ] and [6 ], and [Table 3 ]).
Fig. 5 Resin-bonded bridges (RBBs) after testing. (A ) Enamic, (B ) Y-ZPT, (C ) Suprinity, and (D ) ABS groups, with different mechanical behavior after shear load.
Fig. 6 Details of fractured resin-bonded bridges (RBBs) and more frequent failure modes
by material type. (A ) ENA, adhesive interproximal and cohesive in retainer. (B ) Y-ZPT, adhesive, with RBB integrity. (C ) SUP, cohesive in Frasaco tooth and retainer. (D ) ABS, adhesive in interproximal, cohesive with plastic deformation in RBB (no RBB
tooth loss occurred).
Discussion
The null hypothesis that no differences would be found in the SBS among the tested
materials in the tested RBB model was rejected because significant differences existed
(p < 0.01). Y-ZPT (control) was the most rigid material in this experimental model,
consistent with the literature. The ABS, ENA, and SUP groups exhibited consistent
mechanical performances.
When speaking about the longevity of rehabilitative treatment, one implicitly thinks
of definitive rehabilitation. However, when treating a case of MLIA, rehabilitation
must often be temporary and adaptable. This is the case of orthodontic space opening,
in which success is reflected in the progressive diastema between the central incisor
and the canine tooth. In these specific cases, zirconia RBB is not advisable because
it is too resistant to be removed repeatedly without damaging the supporting tooth
and has a laborious adhesive technique that hinders the addition of resin-matrix-based
materials. Thus, the possibility of fabricating RBBs with materials that are easier
to handle, can be replaced at low cost, or are easier to remove from the supporting
tooth led us to look for alternatives, mainly focusing on managing orthodontic treatments
using aligners that would benefit from a straightforward handling prosthesis.
Adhesion between CAD/CAM materials and teeth substrates depends on adhesive systems[34 ] and chemical interactions that occur between functional monomers and tooth components,[35 ] which in turn depend on the properties of the materials, which are crucial to the
success of adhesive restorations.[22 ] In this experimental setting, RelyX Ultimate cement was used based on recent research[21 ]
[23 ] by its adhesive efficiency and versatility when paired with Y-ZPT, ENA, and SUP
ceramics. Also, adhesive protocols followed literature guidelines.[11 ]
[13 ]
[27 ]
[33 ]
[34 ] Nothing was found in the literature about the adhesive protocol for Medical ABS.
Considering the chemical composition and ease of handling of the material, an old
and well-known hydrophobic resin (Heliobond, Ivoclar Vivadent AG, Schaan, Liechtenstein)
was selected to simplify the adhesive protocol bearing in mind the possibility of
using Medical ABS RBBs as an easily exchangeable interim prosthesis. These adhesive
systems evidenced differences between materials' mechanical behavior and allowed them
to attain the maximal cohesive strength of the adherend. Therefore, should not have
biased the study results.
Regarding CAD/CAM materials, the results showed that the mechanical behavior of RBBs
depends on the type of material. Besides that, anterior RBBs have their clinical survival
dependent on the mechanical resistance of the connector, which is related to its thickness
and bonding surface area. These two variables are especially critical in RBBs replacing
lateral incisors due to occlusogingival and vestibular-palatal anatomic restrictions
related to the available interocclusal space for the restorative material. About this
subject, the literature found is mainly focused on zirconia-veneered frameworks and
the posterior region,[36 ] and a single retainer with a connector diameter of 16 mm2 in the anterior region and 20 mm2 in the posterior region has been suggested with the assumption that periodontal hygiene
might be a concern.[37 ] In the present study, the connector area was set at 6.6 mm2 and the bonding surface area at 42 mm2 following more realistic dimensions suggested in the literature[38 ] (>4.5 and > 35 mm2, respectively) estimated for the Y-ZPT RBB (control) and consequently
for the other materials tested. A recent study[39 ] using finite elements proposes a volume of 9.04 mm3 instead of an area for an anterior connector planned for lithium disilicate, a material
less resistant than zirconia. In any case, there is evidence that an increased cross-sectional
thickness of the connector is desirable.[40 ] Replacing a lateral incisor originates a relatively short cantilever length, which
favors the clinical survival of the restoration.[41 ]
Using Frasaco teeth as adherends was very useful because they have a standardized
composition and anatomy, allowing the elimination of bias originating from biological
factors or different macroanatomies of the palatal face of a natural incisor, which
can occur if natural teeth have been used, as only slight asperization was intended,
as in a minimally invasive approach.[8 ] A practical comparison between the materials used to manufacture single-retainer
RBBs without inherent ethical restrictions was also possible. Despite the expected
low shear strength of Frasaco teeth based on a preliminary study, their resistance
was sufficient to demonstrate differences in the mechanical behavior of the RBBs,
as exclusive adhesive failure was verified only for RBBs manufactured with zirconia,
a material with high toughness.
Transposing the findings to a clinical situation, it can be suggested that using an
RBB made of ENA or SUP as their mode of failure led to the complete loss of the pontic,
the removal of the retainer, and the manufacture of a new restoration would be necessary.
In the case of Y-ZPT, loss of adhesion without RBB structural changes, a fact in line
with the primary failure reported in the literature for this material,[33 ]
[37 ] would allow for an immediate new adhesive procedure. As for the ABS RBB, no information
was found in the literature. This study suggests that its plastic deformation would
allow the patient to have an appointment with the dentist before the pontic is lost,
avoiding being toothless, an advantage over the other tested materials.
Concerning Medical ABS, its low melting point (105°C) makes it ideal for in-office
equipment. It must be highlighted that if manufactured by extrusion-based fused deposition
modeling (FDM), the orientation of the appendages influences its mechanical characteristics.
Therefore, a careful design contemplating this aspect is necessary for an excellent
final mechanical performance.[42 ] The significant benefits of FDM are low cost, rapid prototyping, and simplicity
of procedure.[43 ] Complex geometries with a high concentration of stress should be avoided. However,
if not possible, fabric from powder (SLS—selective laser sintering) should be preferred
because the unused powder fills the gaps between the filaments. Still, this procedure
makes the Medical ABS RBB much more expensive, increases postprocessing time, and
requires extra equipment, such as powder removal stations.[26 ] Reducing the size of the extruder nozzle diameter and the thickness of the layers
reduces the water absorption properties and increases the tensile and flexural strength
of the specimens.[43 ]
One cannot propose RBB as an option to rehabilitate the space of the MLIA without
reflecting on occlusal function. Scientific literature focusing on occlusal efforts
at the anterior level of the maxilla was not found, leading to a more embracing discussion.
A study focusing on the maximum bite force (MBF) refers to a value of approximately
80 N (20% higher in bruxists) in individuals aged 22 to 48 years.[44 ] It varies with malocclusion, sex (higher in males), and age (increase until young
adult age), decreasing significantly with vertical and transverse craniofacial and
dental discrepancies, and with old age.[45 ]
[46 ] Patients with normal sagittal occlusion are expected to have more molar bite force
than patients with malocclusions, with a magnitude two to three times greater in the
molar region than in the anterior region.[47 ] A recent systematic analysis showed that the MBF ranged from 246.22 to 489.35 N
and 5.69 to 16.1 kg in children and adolescents, respectively.[48 ] If a contact area of 1 mm2 is assumed, respective values of 246 to 489 MPa and 0.56 to 158 MPa would be obtained.
However, if the results from T-scan measurements of the occlusal contact area in MBF[49 ] are considered, revealing a mean value of 155 mm2 for healthy young adults, the conversion would be to 0.3 to 3 MPa/mm2 of contact area. Generally, a single-retainer RBB design should be preferred whenever
canine guidance is present. However, with relatively short clinical crowns of the
abutment teeth and limited bonding surface, a two-lingual retainer design might be
preferred if a group function articulation is present.[8 ]
[25 ]
Considering patients treated for MLIA by space opening reflection must be made because
occlusal loads are higher than expected for the average patient whenever hypodivergence
is present.[50 ] However, at the end of orthodontic treatment, an equilibrated occlusal function
is mandatory, with a dispersed distribution of occlusal forces, thus theoretically
reducing the adhesive stress on RBBs in the anterior maxilla.
Extrapolating the results of this study to clinical situations, Y-ZPT RBBs are the
most suitable for MLIA rehabilitation, a finding consistent with the literature and
that validates the choice of this material as the control material used in this study.
However, more research is needed for newer zirconias with higher yttria contents because
of their reduced toughness by almost half. Not testing them, instead of the tougher
third-generation material, is a limitation of this study because newer compositions
with higher yttria content, while improved aesthetically, have lower mechanical performance
and are more susceptible to breakage.[15 ]
[16 ] Thickness, composition, microstructure, and cementing agent are crucial for the
performance of the resistant tetragonal phase of monolithic zirconia,[51 ] advising caution when extrapolating results from research focusing on the longevity
of older materials.[12 ] Although scarce, available randomized clinical trials (RCTs) using newer compositions
have promising results.[38 ] Well-designed RCTs with large sample sizes are still needed to achieve more accurate
results about the clinical success rate of different RBB designs in the anterior region,[24 ]
[25 ] knowing from the start that lower cantilever length and higher occlusocervical thickness
significantly increases load to fracture values.[40 ] One well-controlled RCT,[38 ] some clinical studies,[8 ]
[52 ]
[53 ] and some systematic reviews[54 ]
[55 ] found in the literature revealed high survival rates and good clinical performance
for the single-retainer zirconia RBBs from 18 months up to 15 years, with reported
clinical results comparable or even better than those of the conventional fixed prosthesis
and implant-supported crowns.[8 ]
[37 ]
[41 ]
[53 ]
Still, patients with MLIA situations are frequently adolescents with ongoing maxillofacial
growth,[2 ] and despite there is no sufficient evidence to either indicate or contradict the
usage of dental implants in this age group,[7 ] its implantation requires positional modifications to attend periodontal and aesthetic
factors, and they should be considered only under particular circumstances.[6 ]
[7 ] If infraocclusion of the replaced tooth occurs over time, new prosthetic restoration,
new orthodontic treatment, or distraction osteogenesis may be necessary,[7 ] along with carefully planned rehabilitation treatment that should contemplate interim
rehabilitation.
Whenever the option is short-term interim rehabilitation (orthodontic appliance removal
or adaptation, periodontal remodeling or maturation, a short period between the end
of orthodontic treatment and implant-supported crown placement, or even during the
time of osseointegration of the implant), any other material is feasible and preferable
because of more straightforward adhesive protocols, removal, or marginal adaptation
for tissue management, if desired. For that purpose, printed ABS RBB is an interesting
material. It can be fabricated quickly on the chairside at a low cost.[26 ]
[43 ] It requires only a hydrophobic resin for surface treatment, allowing an easy and
quick cementation technique for minimally invasive rehabilitation. Further research
using this or similar materials should be conducted in the future.
This study used a specific RBB design with a retainer on the palatal side of the central
incisor. This design could raise constraints in cases of minimal interocclusal space
due to sagittal or vertical discrepancies that may coexist in MLIA cases. Alternative
approaches, such as employing a single retainer adhered to the buccal side of the
central incisor or canine tooth, should be considered because of the thin dimensions
of the retainer, which would not invade the buccal profile of the supporting tooth
and a more straightforward cementation technique than the palatal one.
Conclusion
RBBs made of Vita Enamic, Suprinity, Y-ZPT zirconia, or 3D-printed ABS can support
physiological occlusal loads of the anterior maxilla. They can be used to rehabilitate
MLIA in clinical situations. As long as the adhesive protocol is technically well
executed, zirconia is the material of choice for definitive rehabilitation, as, due
to its mechanical resistance, occasional adhesive failure without structural loss
allows for immediate new cementation. If needed, ABS, ENA, and SUP are more suitable
for interim RBBs because of the advantage of easier removal and in-mouth adaptation.
The option for each material depends on the estimated time for use (temporary or permanent
rehabilitation) and the necessity of removal for orthodontic or surgical techniques.