Open Access
CC BY-NC-ND 4.0 · International Journal of Epilepsy 2023; 09(01/02): A1-A40
DOI: 10.1055/s-0044-1791430
E-Poster Abstracts

Alcohol-Related Seizure: A Hospital-Based Study from North East India

Authors

  • Baiakmenlang Synmon

    1   Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India

  • S. R. Sarma

    1   Department of Neurology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India
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Keywords

alcohol-related seizure - AUDIT score - electroencephalogram

Alcohol is one of the leading causes of death and disability globally affecting both the central and peripheral nervous system. Alcohol-related seizure is a common medical emergency in Neurology and Psychiatry departments and is responsible for 20 to 30% of seizure admission.

Materials and Method: A prospective study carried in a referral center in North East India for duration of 1 year. Seizure patients who fulfil the definition of alcohol-related seizure were included. Routine blood work, an electroencephalogram (EEG) and a required neuroimaging was done. Patient's data were collected and analyze.

Results: Thirty four male patients were included with mean age of presentation was 40.79 ± 11.85 years. The mean duration of alcohol intake was 12.82 ± 8.48 years with a range of 3 between last binge of alcohol and onset of seizure was <24 hours in 10 patients (29.4%); 2,440 years. The gap 48 hours in 18 patients (52.9) an >48 hours in 6 patients (17.6%). The mean Alcohol Use Disorders Identification Test (AUDIT) score was 22.8 ± 6.97 and mean Clinical Institute Withdrawal Assessment for Alcohol (CIWA) score was 16.47 ± 7.9. The mean MMSE score in all alcohol-related seizure cases was 26 ± 2.0 and was found to be inversely correlated with duration of alcohol intake (Pearson's coefficient = 0.29). Focal epileptiform changes in EEG was seen in two patients (5.8%), generalized spike and wave seen in one patient (2.9%), and generalized theta slowing seen in 9 patients (26.4%). Presence of an abnormal EEG, a positive past history of seizure related to alcohol, and an AUDIT score >20 are significantly associated with recurrence of seizure.

Conclusion: Abnormal EEG, past history of similar illness, an AUDIT scores of >20 alcohol-related seizure can reoccur; presence of 20 can predict recurrent seizure in these patients.


No conflict of interest has been declared by the author(s).

Publication History

Article published online:
12 September 2024

© 2023. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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