The quality of bowel preparation is crucial for colonoscopy. Polyethylene glycol (PEG)
electrolyte solutions are widely used for their safety and effectiveness in cleansing
the colon. However, the requirement to consume large volumes of water and the speed
of ingestion make the process uncomfortable for patients. To minimize the impact on
patients' lives, this study compares two PEG administration regimens for outpatient
colonoscopy: the (1+2)L PEG regimen and the (2+1)L PEG regimen.
A randomized controlled trial was conducted from October to November 2024, involving
40 patients who were randomly assigned to either the control group (1+2)L PEG or the
observation group (2+1)L PEG. The control group consumed 1L of PEG 10-12 hours before
the procedure and 2L within 4-6 hours before the procedure, while the observation
group consumed 2L 10-12 hours before and 1L within 4-6 hours before the procedure.
The Boston Bowel Preparation Score (BBPS) was used to assess bowel preparation quality.
The impact on sleep was evaluated using a 1-10 scale, with 1 being highly disruptive
to sleep and 10 indicating no disruption. Patient satisfaction was also measured on
a 1-10 scale, with 1 being very dissatisfied and 10 being very satisfied. Statistical
analysis was performed to determine if there were significant differences between
the two regimens.
he bowel preparation quality scores between the two regimens were not statistically
significant. However, the (2+1)L PEG regimen had a statistically significant lower
impact on sleep compared to the (1+2)L PEG regimen, with more patients reporting less
disruption to their sleep. Patient satisfaction was also significantly higher in the
(2+1)L PEG regimen.
For patients undergoing morning colonoscopies, the (2+1)L PEG regimen ensures bowel
preparation quality while having a minimal impact on sleep and increasing patient
satisfaction with the bowel preparation process. This study provides additional options
for bowel preparation regimens.
