Aims Endoscopic ultrasound-guided gastrojejunostomy (EUS-GY) has emerged as a minimally
invasive alternative to surgical treatment for patients with gastric outlet obstruction.
This retrospective study evaluates the initial experience of a tertiary hospital in
performing EUS-GY for patients with various etiologies of gastric obstruction
Methods A total of 23 patients who underwent EUS-GY between November 2022 and September 2024
were included. Demographic characteristics, obstruction etiologies, technical and
clinical success rates, and immediate adverse events were analyzed. Technical success
was defined as the correct placement of a lumen-apposing metal stent (LAMS), while
clinical success was defined as the patient’s ability to tolerate an oral diet. Procedure-related
adverse events were also recorded [1].
Results Of the 23 patients, 18 (78.3%) were male and 5 (21.7%) female, with a mean age of
70 years. Most cases of obstruction were of malignant origin (96%), with pancreaticobiliary
(43.5%) and gastric cancers (43.5%) being the most common causes. The obstruction
site was located in the antrum or pylorus in 10 patients, in the duodenal bulb or
second portion in another 10, and in the distal duodenum in 3 cases. Technical and
clinical success was achieved in 22 patients (95.6%). LAMS of 20x10 mm were used in
19 patients, while 15x10 mm stents were used in 3 cases. Adverse events occurred in
3 patients (13%) due to stent migration. Two cases were successfully managed endoscopically,
while one required surgical intervention. All adverse events were resolved without
persistent complications
Conclusions The initial experience with EUS-GY in our tertiary hospital demonstrates that the
procedure is technically feasible and safe, with high rates of clinical and technical
success and a low incidence of immediate complications. These findings support the
use of EUS-GY as an effective and minimally invasive therapeutic option for patients
with gastric outlet obstruction.
