Clinical Research Informatics: Recent Advances and Future Directions

Summary

Objectives: To summarize significant developments in Clinical Research Informatics (CRI) over the past two years and discuss future directions.

Methods: Survey of advances, open problems and opportunities in this field based on exploration of current literature.

Results: Recent advances are structured according to three use cases of clinical research: Protocol feasibility, patient identification/recruitment and clinical trial execution.

Discussion: CRI is an evolving, dynamic field of research. Global collaboration, open metadata, content standards with semantics and computable eligibility criteria are key success factors for future developments in CRI.

Keywords

Clinical research informatics - protocol feasibility - patient recruitment - clinical trial execution - open metadata - semantic annotation

 

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