DOI: 10.1055/s-00000131

Synfacts

Issue 12 · Volume 9 · December 2013 DOI: 10.1055/s-003-25967

Synform

A145
Zanda, Matteo: SYNFORM ISSUE 2013/12

Synthesis of Natural Products and Potential Drugs

z1255
All PDFs of this category
1255
Synthesis of Nafoxidine via Copper-Catalyzed Carboarylation
1256
Synthesis of Maoecrystal V
1257
Total Synthesis of (±)-Merochlorin A
1258
Divergent Approach to Lycopodium Alkaloids
1259
Synthesis of (–)-Minovincine
1260
Total Synthesis of Ecteinascidin 743
1261
Synthesis of the JAK2 Kinase Inhibitor AZD1480
1262
Synthesis of an MDM2 Inhibitor
1263
Total Synthesis of (+)-Neoxaline
1264
Total Synthesis of (±)-Neofinaconitine
1265
Formal Synthesis of Clopidogrel (Plavix®)
1266
Synthesis of All Four Reboxetine Stereoisomers

Synthesis of Heterocycles

z1267
All PDFs of this category
1267
Diels–Alder Reaction–Fragmentation of Pyridinium Salts and Alkynes
1268
Synthesis of 2-Fluoropyrroles from gem-Difluorocyclopropyl Ketones
1269
Gold-Catalyzed Synthesis of Furan-3-ones via [2,3]-Sigmatropic Rearrangement
1270
Synthesis of Imidazoquinolone Carbonitriles from Tetracyanoethylene
1271
Rh(III)-Catalyzed Regioselective C–H Activation Route to Naphthyridinones
1272
Metalation of 7-Azaindoles
1273
Silver-Catalyzed Synthesis of Oxindoles
1274
Radical Spirocyclization Route to Spirooxindoles
1275
Pyrrolo[2,3-d]pyrimidines Through Activation of N-Benzyl Groups by Distal Amides
1276
Pd-Catalyzed C–H Activation Route to Hydroxy Isoindolones
1277
Synthesis of Pyrido[1,2-b]indazoles from the Reaction of 2-Arylpyridines with NaN3
1278
Ag-Catalyzed [5+2]-Cycloaddition Route to Dihydroazepines
1279
Synthesis of Substituted Coumarins from Propargyl Vinyl Ethers
1280
Rhodium-Catalyzed Synthesis of Benzazepinones
1281
Efficient Heteroannulation Route to 2-Trifluoromethyl Quinolines

Synthesis of Materials and Unnatural Products

z1283
All PDFs of this category
1283
A New Building Block for Low Band Gap Polymers
1284
An Additional Path to [8]Circulenes
1285
Diazo Compounds from Azides in Water
1286
New Approach to the Synthesis of Thienoacenes
1287
Template-Assisted Polymerization Leads to Polymers with Narrow Polydispersity
1288
Dialumene-Benzene as a Synthon for Reactive Dialumenes
1289
Rapid Access to BN-Containing Heptacene Isomers
1290
Regioselective Direct Alkoxylation of Azobenzenes
1291
Dibenzosilaborins: A New Class of Heterocycles
1292
Expanding Cyclopropenes to Bifurans
1293
Tandem Synthesis of Benzo[b]carbazoles
1294
Efficient Synthesis of Dibenzohelicenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1295
All PDFs of this category
1295
Diastereoselective Hydroxytrifluoro-methylation of Dienes Catalyzed by Copper
1296
Binary Acid Catalysis for Asymmetric [4+2]-Cycloaddition Reactions
1297
P-Chirogenic Organocatalysts in the Enantioselective Aza-MBH Reaction
1298
Bifunctional Catalyst: Asymmetric Aldol Reaction Catalyzed by Amino Acid Salts
1299
An S2N2 Ligand for Ru-Catalyzed Asymmetric Hydrogenation of Ketones
1300
Enantioselective Dibromination of Allylic Alcohols by a Titanium Catalyst
1301
Enantioselective Alkylation of Aldehydes with Zinc–2-Pyridylsulfinamides
1302
Iridium-Catalyzed Asymmetric Direct Reductive Amination
1303
Bis(oxazolidine)pyridine Ligands for Asymmetric [3+2] Cycloadditions
1304
Enantioselective Palladium-Catalyzed α-Arylation of Amides
1305
Cu-Catalyzed Enantioselective Alkynylation of Aldehydes
1306
From Enals to Chiral γ‑Amino Alcohols via Asymmetric β-Borylation of Enimines
1307
Spiroindolenines via a Ru-Catalyzed Intramolecular Allylic Dearomatization
1308
Enantioselective Palladium-Catalyzed Allylic Dearomatization
1309
Rh-Catalyzed Olefin Isomerization to Z-Configured α,β-Unsaturated Ketones
1310
Silver-Catalyzed Conjugate Addition of Glycine Imino Esters
1311
Rh-Catalyzed Asymmetric [2+2+2] Cycloadditions of Diynes with Isocyanates
1312
Copper-Catalyzed Stereoselective Henry Reaction
1313
Catalytic Enantioselective N-Sulfonyliminium Cyclization Cascade
1314
Synthesis of Chiral 1,2-Diols via α-Hydroxyacetate Aldol Reaction
1315
Diastereo- and Enantioselective Ni(II)-Catalyzed Alkylation Reactions
1316
Cu(II)-Catalyzed Diastereo- and Enantioselective Synthesis of Pyrrolidines
1317
Enantioselective Rhodium-Catalyzed Formal [4+3] Cycloaddition
1318
DKR of Homoallylic Alcohols Using a Lipase and a Ruthenium Catalyst
1319
Copper-Catalyzed Asymmetric Hydrogenation of Ketones
1320
Haloamination of 3-Alkenyl-oxindoles and Chalcone Derivatives
1321
Enantioselective Cobalt-Catalyzed Addition of Allenes to Silylacetylenes
1322
TRIP-Catalyzed Asymmetric Allylation of Aldehydes
1323
Copper-Catalyzed Enantioselective B–H Insertion Reactions

Metal-Mediated Synthesis

z1325
All PDFs of this category
1325
Fluorination of Aryl Trifluoroborates
1326
Novel Route to Arylsulfones Based on Diaryliodonium Salts
1327
Pd-Catalyzed Alkynylation with Potassium Alkynyltrifluoroborates
1328
Synthesis of γ-Substituted Butanolides from Cyclopropane Hemimalonates
1329
Pd-Catalyzed Carbonylative Coupling of Aryl Halides and Potassium Malonates
1330
Ni(II)-Catalyzed Arylmagnesiation of Alkynes
1331
Arylation of Amino Acid Enolates
1332
Cu-Catalyzed Intermolecular Regioselective Hydroamination of Styrenes
1333
Conjugated Allyl Alcohols through One-Carbon Homologation of Aryl Epoxides
1334
Amide Synthesis via MnO2-Promoted C–H Activation of Methylarenes
1335
Iron-Catalyzed Homocoupling Reaction of Aryllithium Reagents
1336
Pd-Catalyzed β-Arylation of Silyl Ketene Acetals
1337
Zinc-Mediated Synthesis of 1,5- and 1,4,5-Substituted 1,2,3-Triazoles
1338
A General, Pd-Catalyzed Cyanation of (Hetero)Aryl Chlorides and Bromides
1339
Synthesis of Benzothiophenes and Benzoselenophenes Mediated by Copper

Organo- and Biocatalysis

z1341
All PDFs of this category
1341
Bis(amino)cyclopropenylidenes as Alternatives to NHCs in the Stetter Reaction
1342
Bis(guanidino)iminophosphorane-Catalyzed Amination of Ketones
1343
Organotextile Catalysis
1344
Isothiourea-Catalyzed Pyridine Synthesis
1345
Organocatalytic C–H Cross-Biaryl Coupling
1346
Asymmetric Synthesis of Tertiary Thiols from 5H-Thiazol-4-ones and Nitroolefins
1347
A Highly Enantioselective Route Towards α-Methylated Amines
1348
Asymmetric Organocatalysis with Masked Acyl Cyanides
1349
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters
1350
Organocatalytic Enantioselective Decarboxylative Aldol Reaction
1351
Enantioselective Sulfonation of Enones by Cooperative Multicatalysis

Polymer-Supported Synthesis

z1353
All PDFs of this category
1353
Flow Synthesis of Olanzapine
1354
One-Pot Knoevenagel Condensation–Hydrogenation with a Nano-Pd Catalyst
1355
Asymmetric Ring-Opening of meso-Epoxides with a Chiral Metal-Organic Framework
1356
Cu-Catalyzed C–N Coupling in Water with a Polystyrene-Supported Ligand
1357
Synthesis of Tetrasubstituted Pyrroles with H2WO4/SiO2
1358
Synthesis of Nitroalkenes with Polymer-Supported Triphenylphosphine
1359
Cyclization–Cleavage Strategy for the SPS of Cyclic Peptides
1360
Preparation of 2,2′-Biphenols via Suzuki–Miyaura Coupling with Pd/C
1361
Selective Hydrogenation of Nitrobenzenes with Iridium Nanoparticles
1362
Friedländer Quioline Synthesis Promoted by Chitosan-SO3H
1363
ortho-Benzoylation of Phenols Using Fe3O4 Nanoparticles
1364
Oxidative Cross-Dehydrogenative Coupling with CuFe2O4 NPs