Thieme E-Books & E-Journals - Zeitschrift für Gastroenterologie / Issue

P4.01

Khaled, Najib Ben; Zarka, Valentina; Hobeika, Bernard; Schneider, Julia; Rau, Monika; Weich, Alexander; Leicht, Hans Benno; Ye, Liangtao; Piseddu, Ignazio; Dill, Michael; Kandulski, Arne; Pinter, Matthias; Ehmer, Ursula; Schirmacher, Peter; Marquardt, Jens; Mayerle, Julia; De Toni, Enrico; Geier, Andreas; Reiter, Florian Paul: Therapeutische Sequenzen der systemischen Therapie nach Atezolizumab plus Bevacizumab zur Behandlung des HCC: Eine Real-World-Analyse der IMMUreal-Kohorte

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P4.02

Ziegler, Paul Friedrich; Steil, Leif; Salazar, Manuela Gesell; Völker, Uwe; Ribback, Silvia; Dombrowski, Frank: Proteome comparison of pre-neoplastic lesions in different non-cirrhotic models of liver carcinogenesis in mice

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P4.03

Fabritius, Matthias Philipp; Haghpanah, Alireza; Dietrich, Olaf; Puhr-Westerheide, Daniel; Schmidt, Vanessa Franziska; Corradini, Stefanie; Ricke, Jens; Öcal, Osman; Seidensticker, Max: MR guided catheter-based radiotherapy/brachytherapy of liver tumours – first experience and feasibility

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P4.04

Ben Khaled, Najib; Rimassa, Lorenza; Chan, Stephen L.; Sangro, Bruno; Lau, George; Kudo, Masatoshi; Breder, Valeriy; Varela, Maria; Crysler, Oxana; Bouattour, Mohamed; Van Dao, Tu; Faccio, Adilson; Furuse, Junji; Jeng, Long-Bin; Kang, Yoon Koo; Kelley, Robin Kate; Paskow, Michael J.; Makowsky, Mallory; Ran, Di; Negro, Alejandra; Abou-Alfa, Ghassan K.: Five-year overall survival (OS) and OS by tumour response measures from the Phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)

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P4.05

Gaasch, Aurelie; Rogowski, Paul; Marschner, Sebastian; Walter, Franziska; Da Silva Mendez, Vanessa; Hofmaier, Jan; Reiner, Michael; Belka, Claus; Corradini, Stefanie: Single Shot Liver: MR-guided stereotactic body radiotherapy (SBRT) for hepatic malignancies and metastasis

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P4.06

Freutsmiedl, Verena; Seitz, Tatjana; Hellerbrand, Claus: Hepatic stellate cells show protumorigenic effects on melanoma cells

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P4.07

Jochem, Seraphine; Seitz, Tatjana; Hellerbrand, Claus: Expression and function of G protein-coupled receptor 37 in hepatocellular carcinoma

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P4.08

Oecal, Elif; Alunni-Fabbroni, Marianna; Piseddu, Ignazio; Thaler, Matthias; Zacherl, Mathias; Salvermoser, Lukas; Stechele, Matthias M.R.; Burnell, Lu Fornés; Hirner-Eppeneder, Heidrun; Kimm, Melanie; Kimm, Melanie; Rudelius, Martina; Seidensticker, Max; Wildgruber, Moritz; Goldberg, S.Nahum; Ricke, Jens: Immune Modulation in Untreated, Contralateral Hepatic Metastases after Yttrium-90 Radioembolization of Microsatellite Stable Colorectal Cancer

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P4.09

Itzenhäuser, Tatjana; Schildt, Fulya Suzan; Sommer, Judith; Hellerbrand, Claus: Uptake of fatty acids and lipid accumulation promote prometastatic characteristics of colorectal cancer cells

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P4.10

Ehnis, Hanna; Hellerbrand, Claus: The role of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) in hepatocellular carcinoma

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P4.11

Mertens, Alexander; Waldschmidt, Dirk; Luedde, Tom; Berres, Marie-Luise; Modest, Dominik P.; Al-Batran, Salah-Eddin; Loosen, Sven; Roderburg, Christoph; Kandler, Jennis: CLEAN-DUCT / TRITICC-3 (IKF070) – A Phase IIa, Prospective, Single-Arm, Open-Label, Non-Randomized, Multi-Center Pilot Study of Durvalumab+Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

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P4.12

Suhl, Luisa; Ostroumov, Dmitrij; Menze, Arne; Sauer, Sarah; Wedemeyer, Heiner; Kühnel, Florian; Wirth, Thomas: Investigation of CD4 T cell help and MHC II in therapeutic vaccinations against liver cancer

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P4.13

Dayan-Özdurmus, Selin; Seretny, Agnieszka; Butthof, Luise; Breinig, Marco; Tschaharganeh, Darjus: Deciphering genomic dependencies: A systematic exploration of synthetic lethal interactions induced by chromosomal deletions

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P4.14

Buchner, Robert; Alunni-Fabbroni, Marianna; Oecal, Elif; Nardone, Luigi; Gray, Cheryl; Corradini, Stefanie; Ricke, Jens; Wildgruber, Moritz; Seidensticker, Max: Circulating tumor cells predict recurrence risk in early HCC treated with local ablative therapy

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P4.15

Wolf, Stephanie D.; Hammad, Seddik; Müller-Dott, Sophia; Lautwein, Tobias; Köhrer, Karl; Saez-Rodriguez, Julio; Luedde, Tom; Dooley, Steven; Bode, Johannes: TGF-β critically determines the activation state of both, the macrophage subpopulation that is particularly recruited in the context of MASH progression, as well as of TAMs

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P4.16

Kocheise, Lorenz; Kempski, Jan; Tang, Yunhe; Balcar, Lorenz; Berger, Victoria; Tomczak, Miriam; Gorgulho, Joao; Masood, Ramsha; Giehren, Franziska; Schmidt, Constantin; Sutter, Jan P.; Fruendt, Throben W.; Pagani, Francesca; Wulf, Sophie; Kött, Julian; Domanig, Saskia; Giannou, Anastasios; Bedke, Tanja; Lücke, Jöran; Zhang, Tao; Zhang, Siwen; Machicote, Andres; Lohse, Ansgar Wilhelm; Alunni-Fabbroni, Marianna; Ricke, Jens; Ben Khaled, Najib; Pinter, Matthias; Scheiner, Bernhard; Huber, Samuel; von Felden, Johann; Piseddu, Ignazio; Schulze, Kornelius: Serum IL-6 is a prognostic biomarker for advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab

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P4.17

Vazquez, Sonia Jimenez; Butthof, Luise; Hofmann, Ilse; Feucht, Judith; Tschaharganeh, Darjus: Repurposing passenger amplifications for specific therapeutic targeting of liver and other solid cancers

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P4.18

Kurschatke, Leon; Inal, Aslihan; Schirmacher, Peter; Roessler, Stephanie: High expression of SLIT2 in intrahepatic cholangiocarcinoma stroma

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P4.19

Wolff, Timo; Göttert, Simeon; Strand, Dennis; Galle, Peter R.; Strand, Susanne: Analysis of mitotic stress-induced activation of the cGAS/STING signaling pathway in human hepatocytes

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P4.20

Gaitantzi, Haristi; Dooley, Steven; Reißfelder, Christoph; Breitkopf-Heinlein, Katja: BMP-9 – a tumour-suppressive factor in the liver?

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P4.21

Ostroumov, Dmitrij; Sauer, Sarah; Suhl, Luisa; Kumthekar, Aditi; Wedemeyer, Heiner; Kühnel, Florian; Wirth, Thomas: Epitope-flanking amino acid substitutions facilitate enhanced antigen processing and improve anti-tumoral T cell immunity

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P4.22

Dabiri, Yasamin; Alex, Sophie; Calvisi, Diego Francesco; Woelfl, Stefan; Ortmayr, Gregor; Ebert, Matthias; Mikulits, Wolfgang; Dooley, Steven; Chen, Xinlai; Dropmann, Anne: Linker Phosphorylation of Smad3 as a Driver of Cholangiocarcinoma Progression and Chemotherapy Resistance

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P4.23

Calleja, Josune Cabello; Gu, Wenyi; Schierwagen, Robert; Brol, Maximilian Joseph; Uschner, Frank Erhard; Rennebaum, Florian; Groba, Sara Reinartz; Praktiknjo, Michael; Trebicka, Jonel: Trends und Entwicklung des hepatozellulären Karzinoms durch ätiologische Verschiebung von 2005 bis 2020 in Deutschland: Bundesweite bevölkerungsbasierte Studie

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P4.24

Tümen, Deniz; Seitz, Rebecca; Aschenbrenner, Elisabeth; Teubner, Jan Peter; Neumeyer, Katja; Gunckel, Manuela; Pollinger, Kirstin; Mester-Pavel, Patricia; Kunst, Claudia; Gülow, Karsten; Mueller-Schilling, Martina: Targeting p53 Isoforms: A Novel Approach for Anticancer Therapy

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P4.25

Seraphin, Tobias Paul; Özsoy, Adil; Luedde, Tom; Kather, Jakob Nikolas; Brooks, James Alexander; Kallenbach, Michael: Artificial Intelligence for differentiation of focal liver lesions using contrast-enhanced ultrasound (CEUS)

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P4.26

Inal, Aslihan; Casado, Mario Huerta; Baeumlisberger, Freya; Guer, Kira; Sugiyanto, Raisatun-Nisa; Huth, Thorben; Fritzsche, Sarah; Sticht, Carsten; Schirmacher, Peter; Roessler, Stephanie: ROBO receptors function as tumor suppressors in cholangiocarcinoma

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P4.27

Tulessin, Margaret; Roessler, Stephanie; Beckers, Anika; Castven, Darko; Marquardt, Jens; Steiger, Katja; Wirtz, Theresa Hildegard; Berres, Marie-Luise; Groll, Tanja; Mogler, Carolin: In-depth histological evaluation and comparison of mouse models for cholangiocarcinoma studies

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P4.28

Öcal, Osman; Kimm, Melanie; Oecal, Elif; Khaled, Najib Ben; Ricke, Jens; Seidensticker, Max; Wildgruber, Moritz: Predictive Value of Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte ratio in Advanced Hepatocellular Carcinoma Treated with Sorafenib Monotherapy or Combined with Radioembolization

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P4.29

Schlaak, Emilia; D'Alessio, Antonio; Otto-Mora, Patricia; Beck, Jürgen; Päth, Günter; Fulgenzi, Claudia A.M.; Madhava, Pai; Goldin, Robert D.; Scheiner, Bernhard; Korolewicz, James A.; Spalding, Duncan; Ward, Caroline; Nteliopoulos, Georgios; Cai, Heng; John, Chloe; Yip, Vincet; Slater, Sarah; Akarca, Ayse U.; Sodergren, Mikael; Tait, Paul; Habib, Nagy; Thomas, Robert; Cortellini, Alessio; Marafioti, Teresa; Marchesi, Julian R.; Thimme, Robert; Sharma, Rohini; Pinato, David J.; Bengsch, Bertram: Characterization of T cell subsets and dynamic remodeling following immune checkpoint inhibition in hepatocellular carcinoma

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P4.30

Jördens, Markus; Oswald, Hannah; Luedde, Tom; Loosen, Sven; Knoefel, Wolfram; Roderburg, Christoph; Fluegen, Georg: The Impact of Perioperative Infections on Long-Term Survival After Liver Resection for Hepatocellular Carcinoma and Cholangiocellular Carcinoma: A Retrospective Analysis

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P4.31

Marek, Janina; Jiménez, Mirta; Glauß, Sonja; Hanesch, Lorenz; Höchst, Bastian; Altomonte, Jennifer: Chimeric VSV-NDV mediates a multimechanistic therapeutic response supported by immune activation in orthotopic hepatocellular carcinoma

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P4.32

Huang, Chenjun; Qiu, Zhiquan; Huang, Honglian; Xiao, Xiao; Du, Fei; Ji, Jun; Xu, Xuewen; Jiang, Xiaoqing; Ebert, Matthias; Dooley, Steven; Wang, Ying; Gao, Chunfang; Weng, Honglei: Genomic Alterations and Tumor Immune Microenvironment as Predictors of Immunotherapy Outcomes in Advanced Biliary Tract Cancer

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P4.33

Delugré, Fabian: Role of CD44 in early hepatic carcinogenesis in Mdr2 knock-out mice

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P4.34

Cao, Feng; Joechle, Katharina; Liu, Yuanyuan; Seibel, Tobias; Jakhar, Niharika; Raju, Thriveni B.; Chen, Yazhou; Schneider, Carolin Victoria; Meister, Franziska A.: Machine Learning Highlights Association of Body Composition with Cholangiocarcinoma Mortality

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P4.35

Shi, Jing; Ling, Hao; Schulze, Sarah; Holzmann, Bernhard; Mogler, Carolin; Steffani, Marcella; Friess, Helmut; Hüser, Norbert; Hartmann, Daniel: Icer Knockout Influences the Development of Primary Liver Cancer by Promoting Macrophage Infiltration

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P4.36

Enssle, Stefan; Wolfertz, Julia; Schneider, Julia; Hobeika, Bernard; Mansour, Nabeel; Thaler, Matthias; Philipp, Alexander; Rau, Monika; Karin, Monika; Gärtig, Jan; Öcal, Osman; Alunni-Fabbroni, Marianna; Seidensticker, Max; Anz, David; Geier, Andreas; Ricke, Jens; Mayerle, Julia; Reiter, Florian Paul; Toni, Enrico De; Khaled, Najib Ben; Piseddu, Ignazio: Adiposity and myosteatosis are prognostic biomarkers in advanced HCC patients receiving immunotherapy

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P4.37

Jiménez, Mirta; Marek, Janina; Glauß, Sonja; Hanesch, Lorenz; Donakonda, Sainitin; Knolle, Percy; Altomonte, Jennifer; Höchst, Bastian: Immunoregulation and MDSC-Mediated T Cell Paralysis in Hepatocellular Carcinoma Following rVSV-NDV Therapy

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P4.38

Macsek, Peter; Breinig, Marco; Böse, Lio; Butthof, Luise; Wendler-Link, Lena; Seretny, Agnieszka; Dayan-Özdurmus, Selin; Vázquez, Sonia Jiménez; Tschaharganeh, Darjus: LZTR1 acts as a potent tumor suppressor gene in liver cancer by safeguarding aberrant MAPK activity via posttranslational control of RAS GTPases

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P4.39

Brunner, Stefan; Griesshammer, Eva; Bogovic, Niklas; Schlitt, Hans-Jürgen: GLUT1-Positive Immune Cells at the Tumor Interface: Uncovering a Metabolic Pathway to Enhanced Survival in Colorectal Liver Metastases

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P4.40

Wang, Baocai; Kaufmann, Benedikt; Mogler, Carolin; Hüser, Norbert; Friess, Helmut; von Figura, Guido; Hartmann, Daniel: Brg1 suppress DEN-induced hepatocellular carcinogenesis in mice

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P4.41

Brunner, Jessica; Heumann, Philipp; Albert, Andreas; Kandulski, Arne; Mueller-Schilling, Martina; Schlosser-Hupf, Sophie: Impact of Additive Chemotherapy on Survival in Stage IV Colon Cancer Patients Following Liver Metastasectomy: A Retrospective Analysis with a Focus on Chemotherapy Regime Efficacy

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P4.42

Teckentrup, Annika; Stark, Sophie-Marie; Egler, Niklas; Heumann, Philipp; Albert, Andreas; Kandulski, Arne; Gülow, Karsten; Schlosser-Hupf, Sophie; Mueller-Schilling, Martina: How physical activity affects quality of life in patients with UICC IV hepatobiliary and gastrointestinal cancer undergoing systemic therapy

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P4.43

Toth, Marcell; Wan, Shan; Wei, Teng; von Bubnoff, Fabian; Schmitt, Jennifer; Birner, Patrizia; Pinna, Federico; Schirmacher, Peter; Weiler, Sofia; Breuhahn, Kai: The cell polarity protein MPP5/PALS1 controls the subcellular localization of the oncogenes YAP and TAZ in hepatocellular carcinoma

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P4.44

Müller, Christian; Keitel, Verena; Venerito, Marino: Clinical effectiveness of two courses of gemcitabine/cisplatin/durvalumab re-administration after failure of durvalumab maintenance therapy in a patient with intrahepatic cholangiocarcinoma

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P4.45

Kohlhepp, Marlene; Onstein, Julia; Ritz, Thomas; Hundertmark, Jana; Yin, Guo; Liu, Hanyang; de Zarate, Alma Ruiz; Puengel, Tobias; Guillot, Adrien; Tacke, Frank: Inhibition of the chemokine CXCL12 promotes liver cancer progression by modulating the inflammatory and angiogenic tumor microenvironment

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P4.46

Salié, Henrike; Sequeira, Ana Marta; Ijsselsteijn, Marieke; Röttele, Felix; Suo, Yuan; Wischer, Lara; Thimme, Robert; Longerich, Thomas; de Miranda, Noel F.C.C.; Bengsch, Bertram: Batch-effect correction improves downstream imaging mass cytometry data quality and facilitates robust cell type identification in the liver and hepatocellular carcinoma microenvironment

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P4.47

Seretny, Agnieszka; Böse, Lio; Butthof, Luise; Volz, Kai; Tschaharganeh, Darjus: From genotype to phenotype: how IDH1 mutations alter the landscape of intrahepatic cholangiocarcinoma

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P4.48

Büchel, Sarah; Vesper, Niklas; Jühling, Frank; Sagar, Sagar; Godbole, Ira; Bengsch, Bertram; Zeiser, Robert; Berlin, Christopher; Holzner, Philipp; Bronsert, Peter; Baumert, Thomas; Thimme, Robert; Hofmann, Maike; Röhlen, Natascha: Focal Adhesion Kinase (FAK)-Dependent Immune Escape in Hepatocellular Carcinoma

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P4.49

Godbole, Ira; Otto-Mora, Patricia; Bronsert, Peter; Holzner, Philipp; Föll, Melanie; Thimme, Robert; Bengsch, Bertram: Spatial analysis of the tumor immune microenvironment in Biliary Tract Cancer

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P4.50

Ringelhan, Marc; Schuehle, Svenja; van de Klundert, Maarten; Kotsiliti, Elena; Plissonnier, Marie-Laure; Faure-Dupuy, Suzanne; Riedl, Tobias; Lange, Sebastian; Wisskirchen, Karin; Thiele, Frank; Cheng, Cho-Chin; Yuan, Detian; Leone, Valentina; Schmidt, Ronny; Hünergard, Juliana; Geisler, Fabian; Unger, Kristian; Algül, Hana; Schmid, Roland; Rad, Roland; Wedemeyer, Heiner; Levrero, Massimo; Protzer, Ulrike; Heikenwälder, Mathias: Spontaneous HCC development in mice expressing all HBV transcripts is STAT3 dependent and indicates an oncogenic effect of HBx

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P4.51

Makwana, Hardik; Wang, Jie; Wang, Lingyu; Schmiel, Marcel; Zhao, Xinlei; Stroebel, Anton; Eischeid-Scholz, Hannah; Odenthal, Margarete: Deciphering the Role of LSD1 in Hepatocellular Carcinoma: Implications for Cell Proliferation and Energy Homeostasis

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P4.52

Pangerl, Maria; Guenther, Rainer: Spontanous bacterial peritonitis caused by Listeria monocytogenes – a possible indicator for Carcinoma

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P4.53

Karin, Monika; Radushev, Kaloyan; Rössler, Daniel; Oecal, Elif; Böttcher, Katrin; Gray, Cheryl; Schneider, Julia; Enssle, Stefan; Wildgruber, Moritz; Seidensticker, Max; Piseddu, Ignazio; Geier, Andreas; Mayerle, Julia; Ricke, Jens; De Toni, Enrico; Ehmer, Ursula; Reiter, Florian Paul; Khaled, Najib Ben; Alunni-Fabbroni, Marianna: PD-L1 expressing circulating tumor cells to predict survival in patients with advanced hepatocellular carcinoma treated with immunotherapy: a prospective, multicenter study

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Zeitschrift für Gastroenterologie