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Klin Padiatr 2020; 232(02): 70-72
DOI: 10.1055/a-1108-1699
DOI: 10.1055/a-1108-1699
Short Communication
A Ventriculoperitoneal Shunt Infection Successfully Treated with Intraventricular Coadministration of Tigecycline and Colistin
Eine ventrikuloperitoneale Shunt-Infektion wurde erfolgreich mit gleichzeitiger Gabe von intraventrikulärem Tigecyclin und Colistin behandeltFurther Information
Publication History
Publication Date:
10 March 2020 (online)
Introduction
Hemophagocytic lymphohistiocytosis (HLH) is a systemic inflammatory disorder characterized by uncontrolled histiocytic proliferation, hemophagocytosis, macrophage activation, and up-regulation of inflammatory cytokines (Grom AA., Current opinion in rheumatology 2003; 15: 587–590). HLH is usually divided into two types: primary (familial) HLH and secondary (reactive) HLH. Primary HLH is associated with primary immune deficiencies in which specific gene mutations play an important role, such as perforin defects.