Reply to Singh et al.

We would like to thank Dr. Singh and colleagues for their interest in our article [1]. Regarding the endoscopic therapy of GOV1, our previous prospective and retrospective studies both showed that glue injection could be more effective than banding ligation for acute hemostasis and was associated with fewer episodes of ulcer bleeding [2] [3].

The sizes of gastric varices were shown in Table 1. The majority of both groups had moderate or severe gastric varices. Possibly because of the small sample size, no correlation existed between variceal size and acute hemostasis.

It is true that experience is required in performing the glue injections. In this trial, all three endoscopists had good levels of experience in the technique of glue injection.

Publication History

Article published online:
27 January 2021

• References

• 1 Lo GH, Lin CW, Tai CM. et al. A prospective, randomized trial of thrombin versus cyanoacrylate injection in the control of acute gastric variceal hemorrhage. Endoscopy 2020; 52: 548-555
• 2 Lo GH, Lai KH, Cheng JS. et al. A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in management of bleeding gastric varices. Hepatology 2001; 33: 1060-1064
• 3 Lo GH, Lin CW, Perng DS. et al. A retrospective comparative study of histoacryl injection and banding ligation in the treatment of acute type 1 gastric variceal hemorrhage. Scand J Gastroenterol 2013; 48: 1198-1204