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Horm Metab Res 1972; 4(5): 388-391
DOI: 10.1055/s-0028-1094041
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© Georg Thieme Verlag KG Stuttgart · New York

Pseudohypogonadism: Defective Masculinization in a Subject with Normal FSH, ICSH and Testosterone Secretion

E.  del Pozo [*]
  • USA General Hospital, Medical Service, Frankfurt/Main, Germany
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

A 19-year old male is presented with clinical signs of hypoandrogenism but normal excretion of FSH, ICSH and testosterone. In addition, the Clomiphene stimulation test had revealed a normal hormonal reserve. Cariotypes taken from blood and skin ruled out mosaicism as a possible cause. These findings and the absence of response to exogenous testosterone suggested peripheral resistance to androgen. The name "pseudo-hypogonadism" is again suggested for this rare condition in which defective masculinization is at variance with the hormonal studies which are normal.

Key words

Pseudohypogonadism - FSH - ICSH - Testosterone

1 Present address: Oberematt Str. 88, CH-4122 Pratteln, Switzerland

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